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1
Medical economics of automatic hematology
analysis: expenses optimisation of
hematology analyzer for clinical diagnostic
laboratories
Novikov M.I., expert in hematology, Ph. D.
2
Coulter Ac*T Diff
Advia 60
Micros 60-OT 18
Celltak MEK 6400
Models of hematology analyzers delivered in clinics
by National project “The Health”
3
How to supply the devices with expendables?
4
Essential expendables for hematology analyzer
Hematology reagents Special blood
collecting tubes
Hematology controls
5
Volume of reagents
according to 100 analyses
100 tubes
100 patients per a
day
Material for
everyday QC-
procedures
Essential expendables for hematology analyzer
6
Expenses on hematology reagents for the instruments
by “Health”-project
Instrument model 1 analysis cost Quarter expenses
Advia 60 23 RUR 135000
Micros 60 11 RUR 66000
Coulter AcT Diff 13 RUR 78000
Celltak MEK64xx 7 RUR 42000
7
Expenses for tubes with anticoagulant
1 tube costs approx. 12
RUR
Quarter expenses approx.
70 thousands RUR
8
Expenses on hematology controls
1 vial costs approx. 2
thousands RUR
Quarter expenses approx.
5 thousands RUR
9
Entire budget on hematology analyzer’s supply
Total, thousand RUR
Model QUARTER YEAR
Advia 60 210 840
Micros 60 140 560
Coulter AcT Diff 153 612
Celltak MEK64xx 117 468
10
Entire budget on hematology analyzer’s supply
11
Calculating error influence on clinical interpretation of
analysis
Mean RBC=5,4
0
1
2
3
4
5
6
7
0 10 20 30 40 50 60 70
Номер измерения
Value
Mean RBC=5,4
0
1
2
3
4
5
6
0 10 20 30 40 50 60 70
Номер измерения
Value
Test panel
Constant of variation 10%
Automatic blood cell counter
Constant of variation 1%
Series of consequent measurements of hematology controls with RBC value known
to be 5,4
12
How to reduce the expenses on the instrument?
13
Budget is quite limited. How to manage the means?
Model Total, thousand RUR
Laboratory has to reduce
QUARTER YEAR
Advia 60 210 -> 70 280
Micros 60 140 -> 70 280
Coulter AcT Diff 153 -> 85 340
Celltak MEK64xx 117 -> 70 280
14
On what dergee can we reduce 1 analysis costs?
Model 1 analysis cost Quarter expenses
Advia 60 23 -> 4,5RUR 29000
Micros 60 11-> 4,5 RUR 29000
Coulter AcT Diff 13 -> 7,5 RUR 44000
Celltak MEK64xx 7 -> 4,5 RUR 29000
15
Solving reagent supply problem with Unimed reagent
factory
16
1 analysis costs using the reagents “Unimed-Boule” on some
models of instruments
Model of instrument Analysis price
Advia 60 4 RUR.
Micros 60 4 RUR.
Coulter AcT Diff 7 RUR.
Celltak MEK64xx 4 RUR.
17
Hematology reagents “Unimed-Boule” – what for?
Expenses reduce
Allows the laboratory
to supply itself with
reagents 2 times more
18
Weak assembly sets of hematology analyzer
High clearance filters
Peristaltic pump hose
19
Hematology controls Boule Con
Intended for use on a models:
 Medonic CA 620/530, M-series (Boule Medical)
 Unicell, Swelab AC EO+ series (Boule Medical)
 Celltak MEK 6400, 6410 (Nihon Kohden)
 Coulter AcT Diff (Beckman Coulter)
 Micros (ABX)
 Advia 60 (Bayer)
 Sysmex KX-21 (Sysmex)
 BC 3000 series (Mindray)
 Cell-Dyn 1700 (Abbott)
 Abacus (Diatron)
 other models
20
Handmade and industrial tubes: what is the
difference?
EDTA
crystallsMicrotube of serial
manifacture
Handmade tube with
anticoagulant
200
Main source of mistakes
during the sampling!!!
21
Tubes with anticoagulant Univet
Exact quantity of anticoagulant for complete sample
stabilization 200 mkl
Has a mark of appropriate sample volume - 200
mkl.
Fine-dispersed anticoagulant on a bottom of tube
Around bottom for easy sample mixture and
preventing the cell sedimentation
Lustreless area on a surface for sample labeling
22
How to use Univet flasks
Bringing a blood sample in Sampling the blood for test

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Medical Economics of Automatic Hematology Analysis

  • 1. 1 Medical economics of automatic hematology analysis: expenses optimisation of hematology analyzer for clinical diagnostic laboratories Novikov M.I., expert in hematology, Ph. D.
  • 2. 2 Coulter Ac*T Diff Advia 60 Micros 60-OT 18 Celltak MEK 6400 Models of hematology analyzers delivered in clinics by National project “The Health”
  • 3. 3 How to supply the devices with expendables?
  • 4. 4 Essential expendables for hematology analyzer Hematology reagents Special blood collecting tubes Hematology controls
  • 5. 5 Volume of reagents according to 100 analyses 100 tubes 100 patients per a day Material for everyday QC- procedures Essential expendables for hematology analyzer
  • 6. 6 Expenses on hematology reagents for the instruments by “Health”-project Instrument model 1 analysis cost Quarter expenses Advia 60 23 RUR 135000 Micros 60 11 RUR 66000 Coulter AcT Diff 13 RUR 78000 Celltak MEK64xx 7 RUR 42000
  • 7. 7 Expenses for tubes with anticoagulant 1 tube costs approx. 12 RUR Quarter expenses approx. 70 thousands RUR
  • 8. 8 Expenses on hematology controls 1 vial costs approx. 2 thousands RUR Quarter expenses approx. 5 thousands RUR
  • 9. 9 Entire budget on hematology analyzer’s supply Total, thousand RUR Model QUARTER YEAR Advia 60 210 840 Micros 60 140 560 Coulter AcT Diff 153 612 Celltak MEK64xx 117 468
  • 10. 10 Entire budget on hematology analyzer’s supply
  • 11. 11 Calculating error influence on clinical interpretation of analysis Mean RBC=5,4 0 1 2 3 4 5 6 7 0 10 20 30 40 50 60 70 Номер измерения Value Mean RBC=5,4 0 1 2 3 4 5 6 0 10 20 30 40 50 60 70 Номер измерения Value Test panel Constant of variation 10% Automatic blood cell counter Constant of variation 1% Series of consequent measurements of hematology controls with RBC value known to be 5,4
  • 12. 12 How to reduce the expenses on the instrument?
  • 13. 13 Budget is quite limited. How to manage the means? Model Total, thousand RUR Laboratory has to reduce QUARTER YEAR Advia 60 210 -> 70 280 Micros 60 140 -> 70 280 Coulter AcT Diff 153 -> 85 340 Celltak MEK64xx 117 -> 70 280
  • 14. 14 On what dergee can we reduce 1 analysis costs? Model 1 analysis cost Quarter expenses Advia 60 23 -> 4,5RUR 29000 Micros 60 11-> 4,5 RUR 29000 Coulter AcT Diff 13 -> 7,5 RUR 44000 Celltak MEK64xx 7 -> 4,5 RUR 29000
  • 15. 15 Solving reagent supply problem with Unimed reagent factory
  • 16. 16 1 analysis costs using the reagents “Unimed-Boule” on some models of instruments Model of instrument Analysis price Advia 60 4 RUR. Micros 60 4 RUR. Coulter AcT Diff 7 RUR. Celltak MEK64xx 4 RUR.
  • 17. 17 Hematology reagents “Unimed-Boule” – what for? Expenses reduce Allows the laboratory to supply itself with reagents 2 times more
  • 18. 18 Weak assembly sets of hematology analyzer High clearance filters Peristaltic pump hose
  • 19. 19 Hematology controls Boule Con Intended for use on a models:  Medonic CA 620/530, M-series (Boule Medical)  Unicell, Swelab AC EO+ series (Boule Medical)  Celltak MEK 6400, 6410 (Nihon Kohden)  Coulter AcT Diff (Beckman Coulter)  Micros (ABX)  Advia 60 (Bayer)  Sysmex KX-21 (Sysmex)  BC 3000 series (Mindray)  Cell-Dyn 1700 (Abbott)  Abacus (Diatron)  other models
  • 20. 20 Handmade and industrial tubes: what is the difference? EDTA crystallsMicrotube of serial manifacture Handmade tube with anticoagulant 200 Main source of mistakes during the sampling!!!
  • 21. 21 Tubes with anticoagulant Univet Exact quantity of anticoagulant for complete sample stabilization 200 mkl Has a mark of appropriate sample volume - 200 mkl. Fine-dispersed anticoagulant on a bottom of tube Around bottom for easy sample mixture and preventing the cell sedimentation Lustreless area on a surface for sample labeling
  • 22. 22 How to use Univet flasks Bringing a blood sample in Sampling the blood for test

Editor's Notes

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