Lentz unm school presentation slides

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Lentz unm school presentation slides

  1. 1. A Research Career: There WasA Research Career: There WasAlways Another Research QuestionAlways Another Research QuestionMartha J Lentz, PhD, RNScholarship Day May 2013College of NursingUniversity of New Mexico
  2. 2. Polar PlotPolar Plot
  3. 3. Temperature & Sleep CycleTemperature & Sleep Cycle
  4. 4. Hester McLaws Fund UW SONAmerican Nurses Foundation
  5. 5. Mostly I learned, without helpMostly I learned, without helpeven a small study is not possible.even a small study is not possible.
  6. 6. Perimenstrual SymptomsPerimenstrual SymptomsNU1054National Center for Nursing ResearchNational Institutes of HealthNancy Woods PhD, RN, FAAN
  7. 7. Test-Retest Reliability &Stability EstimatesTest retest reliabilityr =r12r23/r13Stability estimatess12=r13/r23s23=r13/r12s13=r132/r12r23
  8. 8. Fluid RetentionReliability coefficient r = .74Stability coefficient s13 = .55
  9. 9. FluidStandard cycle days252321191715131197531Meanscore121086420GroupLow sxPMSPMM
  10. 10. Home SleepNR-01118, P30 NR 004001National Institute of Nursing Research NationalInstitutes of HealthJoan Shaver, PhD, RN, FAAN
  11. 11. In Home Sleep RecordingIn Home Sleep Recording
  12. 12. Home Study-Insomnia TypesHome Study-Insomnia TypesSelf-reported Insomnia N=101Of ThesePP-type (3 noc <85% Slp Efficiency) N=33SO-type (3 noc >88% & 0 noc <85%) N=18Unclassified (fewer 3 noc <85%) N=50Self-reported good sleep N=30Of TheseControl (3 noc >88% & 0 noc <85%) N=14
  13. 13. What is sleep?What is sleep?Self-report the experience of sleepPSG- brain wave activityActigraphy movement
  14. 14. What does saying I have goodWhat does saying I have goodsleep or poor sleep mean?sleep or poor sleep mean?Good sleep is what I am used to experiencingPoor sleep, if different from past experienceDoes PSG poor sleep arise from samemechanism in self-reported good and poorsleepers?Are subtle PSG differences making the mis-match of self-report and PSG sleep quality?
  15. 15. Delta DeprivationUW School of Nursing Intramural FundP30 NR 004001
  16. 16. DeltaAlphaAlpha/DeltaDelta
  17. 17. Jim Rothermel, Res Scientist & Stacy Riffle, RN Res. Nurse
  18. 18. Median Percent of DeltaActivity vs Baseline Night01020304050607080Night 1 Night 2 Night 3n= 12
  19. 19. Bodily Feelings ScaleMusculoskeletal13.51414.51515.51616.51717.5Baseline Morning 1 Morning 2 Morning 3p<.01p<.01n= 12
  20. 20. Median Pressure in KG toReport of Pain0123456Baseline Morning1Morning2Morning3p<.02n= 7
  21. 21. Sleep In Women With andWithout FibromyalgiaNR-04001, P30 NR 004001National Institute of Nursing ResearchNational Institutes of Health
  22. 22. MacroMacro SleepSleep MeasuresMeasuresFibromyalgian = 33Controln = 30Sleep Period Time (min) 454.4±53.4 454.8±30.0Total Sleep Time (min) 392.8±55.3 429.2±28.9REM (min) 89.8±32.6 105.3±20.0SWS 10.4% ± 8.5 12.2% ± 5.8Wake (min) 58.9±40.5 25.3±11.2
  23. 23. Sleep Spindles in NREM Stage 2 inFibromyalgia and Control WomenSleep Spindle Variables Fibromyalgian = 33Controln = 30Number/minute in Stage 2, (± SD)* 3.85 ± 2.1 5.4 ± 2.9Duration, mean seconds, (± SD)** 1.2 ± 0.2 1.1 ± 0.2Spindle Time/epoch Stage 2, (± SD) *** 1.7 ± 1.2 2.7 ± 1.8•Data are from C3; t-test, * P ≤ 0.02; ** P ≤ 0.03; *** P ≤ 0.02.
  24. 24. Growth Hormone Across NocGrowth Hormone Across NocBy GroupBy Group
  25. 25. Delta IncreaseUW School of Nursing Intramural FundP30 NR 004001National Institute of Nursing ResearchNational Institutes of Health
  26. 26. Ways to Increase SWSSleep DelayWhole Body Warming
  27. 27. Delta After Whole BodyDelta After Whole BodyWarmingWarmingNon-REM Cycle4.003.002.001.00Sum600.00400.00200.000.00WarmingBaseline
  28. 28. Armitage CFS Twin SleepDelay Delta
  29. 29. Nocturnal Asthma in ChildrenUW School of Nursing Intramural FundNR-08238, P30 NR 004001, T32 NR007106National Institute of Nursing ResearchNational Institutes of HealthGail Kieckhfer, PhD, ARNP
  30. 30. Study ProceduresAt Home for 1 WeekDaily Peak FlowDaily Symptom DiaryWrist Actigraphy
  31. 31. Laboratory ProceduresPSG
  32. 32. Laboratory ProceduresPulmonaryFunctionFEV 1FEV 25-75eNo
  33. 33. FEV 25-75FEV 25-75sessionUB+8hoursaftersleeponsetUB+4 hrsaftersleeponsetusualbedtime(UB)Mean1101009080706050UB+8hoursaftersleeponsetUB+4 hrsaftersleeponsetusualbedtime(UB)Does the child have a diagnosis of asthma?yesnoError bars: 95% CIfef25_75 sleep delaynightfef25_75 baselinenight
  34. 34. eNOeNOsessionUB+8hoursaftersleeponsetUB+4 hrsaftersleeponsetusualbedtime(UB)Mean35.0030.0025.0020.0015.0010.005.00UB+8hoursaftersleeponsetUB+4 hrsaftersleeponsetusualbedtime(UB)Does the child have a diagnosis of asthma?"yesnoError bars: 95% CIMNO sleep delay nightMNO baseline night
  35. 35. Contingent ProbabilityNight CoughChild ReportParentReportNot atallA littlebitSomewhatA lotNot atall 95%100%A littlebitA littlebitA lotNR100%Without Asthma75%100%With Asthma
  36. 36. Contingent ProbabilityNight CoughChild ReportParentReportNot atallA littlebitSomewhatA lotNot atall 95%15% 4% 2% 100%A littlebitA littlebitA lotNR100%Without Asthma75%100%With Asthma
  37. 37. NapsNapsNon-NappersN=37NappersN=17Asthma N (%) N (%)Yes 15 (40.5) 12 (70.6) p<0.05No 22 (59.5) 5 (29.4)
  38. 38. Mean SD Mean SDPvaluesleep onset 22.35 (0.83) 23.09 (1.33) 0.04 *sleep offset 7.36 (0.85) 7.52 (0.87) 0.52total sleep, min 465.47 (41.22) 437.60 (54.42) 0.04 *sleep onset var. 0.64 (0.36) 1.08 (0.53) <0.01 *Actigraphy VariablesNon-NappersN=37NappersN=17
  39. 39. Mean SD Mean SDPvaluesleep onset 22.35 (0.83) 23.09 (1.33) 0.04 *total sleep, min 465.47 (41.22) 437.60 (54.42) 0.04 *sleep onset var. 0.64 (0.36) 1.08 (0.53) <0.01 *Actigraphy VariablesNon-NappersN=37NappersN=17
  40. 40. Mean SD Mean SDPvaluesleep onset 22.35 (0.83) 23.09 (1.33) 0.04 *sleep onset var. 0.64 (0.36) 1.08 (0.53) <0.01 *Actigraphy VariablesNon-NappersN=37NappersN=17
  41. 41. Motivational Interviewing
  42. 42. Talk ResearchClarify & Sharpen ConceptsDeepen and Extend ConceptualRelationshipsIdentify Implicit AssumptionsGet to Core of What We Know

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