Open Access in Medicine -
Overview Martin Fenner Klinik für Hämatologie, Hämostaseologie, Onkologie und Stammzelltransplantation
Open Access The author(s) grant(s)
to all users a free, irrevocable right of access to, and a license to copy, use and distribute the work publicly and to make and distribute derivative works, subject to proper attribution of authorship. A complete version of the work and all supplemental materials is deposited (and thus published) in at least one online repository. Berlin Declaration on Open Access 2003
PubMed comprises more than 19
million citations for biomedical articles from MEDLINE and life science journals. Citations may include links to full-text articles from PubMed Central or publisher web sites.
Availability of fulltext articles Matsubayashi
et al. in PubMed in 2005 Figure 1 Full text availability of sample articles (n54,667) Matsubayashi M et al. J Med Libr Assoc. 2009 the 8 countries accounting for the journal’s publishers (72.1%). PMC (26.0%) was the ratios. Among second most common method of access, followed by largest number of articles in the sample, the rate at doi: 10.3163/1536-5050.97.1.002. which OA articles were published by authors residing journal platforms or portal sites (17.4%). In contrast, the percentage of OA articles available in Canada was the highest (37.6%), with the United
Distribution of PubMed Open Access
articles from Germany in 2005 Journal Website PubMed Central Institutional Repository Author’s Website 0% 20% 40% 60% 80% Matsubayashi M et al. J Med Libr Assoc. 2009 doi: 10.3163/1536-5050.97.1.002.
NIH Public Access Policy Starting
May 25, 2008, peer-reviewed journal manuscripts that arise from NIH funds have to be submitted to PubMed Central upon acceptance for publication. These papers have to be made accessible to the public on PubMed Central no later than 12 months after publication.
The 20 most popular journals
in my reference manager (about 1700 papers) include 1 Open Access journal: PLoS Medicine 3 Journals without an institutional subscription: Cell Lancet Oncology Nature Reviews Clinical Oncology
atego- orable atients 100 -nega-
90 1 and 80 or out- 70 urvival Mutant CEBPA ates of 60 ely. 50 Mutant NPM1 on the 40 without FLT3-ITD e was 30 recent 20 D mu- Other genotypes 10 P<0.001 tcome 0 s with 0 1 2 3 4 5 6 7 8 9 10 , FLT3- ciated enetic Other genotypes 266 153 90 68 39 22 15 9 7 4 0 red in Mutant NPM1 without 150 123 101 75 56 38 25 14 10 4 2 FLT3-ITD of pa- Mutant CEBPA 67 54 39 30 19 13 8 6 5 3 0 e were nosti- Figure 2. Kaplan–Meier Survival Estimates, According to Genotype. with- Schlenk R et al. NEJM 2008 doi:10.1056/NEJMra063728 Data are shown for relapse-free survival (Panel A) and overall survival (Panel B). “Other genotypes” is defined as the FLT3-ITD genotype and the FLT3- ICM AUTHOR: Schlenk (Dohner) RETAKE 1st
Impact Factor A = the
number of times articles published in 2007 and 2008 were cited by indexed journals during 2009 B = the total number of "citable items" published in 2007 and 2008. ("Citable items" are usually articles, reviews, proceedings, or notes; not editorials or Letters- to-the-Editor.) 2009 impact factor = A/B Calculated (and sold) by
biological. PLoS Computational Biology and
PLoS s are expected to cross this threshold in ed self-sufﬁciency almost immediately affordable price, and cost-effective to Published Articles publishes research on bacteria, PLoS Genetics reﬂects Coverageand PLoS Pathogens Operating Expense the full breadth PLoS ONE is an innovative, interactive journal fungi, parasites, prions, and viruses that interdisciplinary nature of genetics and genomics that publishes peer-reviewed rigorous research (% of operatingby publishing original contributions in contributes to our understanding of the biology research expense covered by operating revenues) within science and medicine. from all disciplines of pathogens and pathogen-host interactions. all areas of biology. % 100 submitted 90 published “ Working in conjunction with other advocacy groups, PLoS has been 80 part of a small, but inﬂuential, team that has changed public policy. Today, the NIH requires everyone supported by an NIH grant to 70 make their results publicly available in PubMed Central within one year of publication.” 60 – Dr. Harold E. Varmus, PLoS Co-founder, Chairman of the Board 50 9 40 PLoS Progress Report 30 PLoS Neglected Tropical Diseases is the ﬁrst 20 OA journal devoted to publishing research on PLoS ONE all scientiﬁc, medical, and10 public health aspects of the forgotten diseases affecting the world’s forgotten people. 0 2005 2006 2007 2008 2003 2004 2005 2006 2007 2008 PLoS Progress Report June 2009: http://www.plos.org/downloads/progress_report.pdf
The process of submitting a
manuscript to a biomedical journal is time-consuming, requires skills that most scientists are not trained in, and is not standardized. The submission of an accepted manuscript to an institutional repository (green OA) is additional work with many of the same characteristics.
Publication charges (2009) Nature Communications
(starts 2010) 5.000 $ PLoS Medicine 2.900 $ EMBO Journal 2.795 $ Blood 2.000 $ BMC Cancer 1.690 $ PLoS ONE 1.200 $ BMJ 0$ Cancer Research (subscription access) charges $75 for submission and $85 per page for accepted manuscripts
H Open Access vs. subscription
access articles during the ﬁrst six months after publication 120 The negative b Increase in downloads and visitors (%) no c that open access r di itat in ffe io 80 5% (incident rate re ns 0.81 to 1.10; P=0. nc expected citation e 40 1.55; P=0.716), al significantly differ 0 A supplementa on the same set o -40 Abstract Full text PDF Unique visitors open access publi being cited by Fig 2 | Percentage differences (95% confidence intervals) in confidence interv Davisdownloads of open access articles (n=247) andarticle downloads, and table at PM et al. Open access publishing, subscription mentary access articles (n=1371) during the first six months after although this effe citations: randomised controlled trial. BMJ publication. Downloads from known internet robots are 2008. excluded doi:10.1136/bmj.a568 DISCUSSION
First issue April 2010, accepts
submissions since October 2009 Aims for papers similar to Nature, but without the same broad impact Hybrid publishing model, costs calculated for 100% Open Access Online only, no editorials, news, etc.
Press Release Nr. 57 (October
13, 2009) Die Deutsche Forschungsgemeinschaft (DFG) baut ihre Unterstützung des Open-Access-Publizierens konsequent aus. Universitäten können künftig bei der DFG Mittel beantragen, um Publikationen ihrer Wissenschaftlerinnen und Wissenschaftler in 24 originären Open-Access-Zeitschriften zu finanzieren. Deutsche Forsc