The MRF
Meningococcus Genome Library
www.meningitis.org/research/genome

Dorothea Hill
University of Oxford
MRF conference...
‘Publicly accessible data requires a stable home and
someone to pay the mortgage.’ Dr. Francine Berman, Research Data Alli...
Whole-genome population structure with ‘Genome Comparator’:
two CC269 (lineage 2) sub-lineages.

lineage 2.2

261 loci

In...
Community improvement of the MRF Genome Library.

dorothea.hill@zoo.ox.ac.uk
Jolley, K. and M. Maiden, Automated extractio...
Meningococcal Reference Unit:
Ray Borrow, Jay Lucidarme, Steve Gray

Pathogen genomics:
Julian Parkhill, David Harris

Mai...
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The MRF Genome Library: Epidemiology of meningococcal disease-causing lineages in England and Wales from 2010/11 to 2011/12

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Dorothea Hill's presentation on her poster at Meningitis Research Foundtion's 2013 conference, Meningitis & Septicaemia in Children & Adults

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The MRF Genome Library: Epidemiology of meningococcal disease-causing lineages in England and Wales from 2010/11 to 2011/12

  1. 1. The MRF Meningococcus Genome Library www.meningitis.org/research/genome Dorothea Hill University of Oxford MRF conference 2013 Wednesday 6th November
  2. 2. ‘Publicly accessible data requires a stable home and someone to pay the mortgage.’ Dr. Francine Berman, Research Data Alliance Funding MRU: Isolates Illumina genome sequencing BIGS database http://pubmlst.org
  3. 3. Whole-genome population structure with ‘Genome Comparator’: two CC269 (lineage 2) sub-lineages. lineage 2.2 261 loci Incl. ST-275, ST-1161 lineage 2.1 Incl. ST-269, ST-467, ST-283 451 loci lineage 5 (CC32) 100 loci
  4. 4. Community improvement of the MRF Genome Library. dorothea.hill@zoo.ox.ac.uk Jolley, K. and M. Maiden, Automated extraction of typing information for bacterial pathogens from whole genome sequence data: Neisseria meningitidis as an exemplar. Euro Surveill, 2013.
  5. 5. Meningococcal Reference Unit: Ray Borrow, Jay Lucidarme, Steve Gray Pathogen genomics: Julian Parkhill, David Harris Maiden Group: Martin Maiden, Keith Jolley, James Bray

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