Exhibition design for St George’s
University of London Pathology
• This power point presentation contains work
currently displayed in the Pathology Museum
at St George’s University of London.
• The audience: The exhibition was designed
as an educational tool for A -Level, ‘Access to
Medicine students’ and Medical students at St
• The exhibition:
– Topic: TB
– Method: Questions listed in the pamphlet, (see
word document) act to guide students through this
– Content: a poster (see subsequent slides), x-rays
(mounted on a light box),‘handling specimens’ and
specimen pots from the Pathology Museum
collections (lungs, brain, liver, kidneys and a half
– Each of the specimens pertains to the mode of
disease suffered by the patient: ‘Sarah’ .
• See subsequent slides for exhibition content.
Why is TB an important
disease to study?
TB currently infecting ‘one third of the World’s
population (2)’. The World Health
Organisation (WHO) has ‘declared TB a public
health emergency’ (4).
TB is highly contagious - if left untreated, each
infected person will pass TB on to ‘between 10
and 15 people every year’ (7).
TB is not limited to the Developing World.
Today, in the UK, over ‘6,500 cases are
reported each year.’ (5)
For this reason TB is a ‘notifiable disease’ –
by law an incident of TB must be reported to
Governmental and Medical authorities to
ensure effective treatment and control.
Most importantly - today, TB is both curable
and controllable. But, less than 50 years
ago, before the discovery of the antibiotic
Streptomycin, this was not the case.
Follow the story of Sarah Finnegan to
learn more about the transmission,
Infection, control and cure of TB.
A Case Study: Sarah Finnegan
She had lost a considerable amount of weight, was
suffering from diarrhea and painful, frequent
Upon examination Sarah was pale, restless, sweating,
and complained of pain in her chest, back and head.
There was a large swelling over her right hip.
• A chest x-ray
• A cerebro-spinal fluid (CSF) sample, taken by
• Blood sample was taken.
• Sputum sample taken.
Upon admission, Sarah was given a course of
streptomycin. Initially her condition improved, but
after a number of weeks Sarah’s headaches became
more frequent and severe. Unable to combat the TB
that had infected her brain, sadly, Sarah slipped into
a coma and died, four weeks after admission.
Sarah Finnegan is a fictitious character inspired by the specimens on display in the Pathology Museum.
Examine the display specimens to see how
Sarah's body may have been affected by TB
On December the 4th
1941 at 21:34, Sarah
Finnegan*, aged 19
years, was admitted to
St George’s Hospital with
a fever (37.8ºC), severe
chest pain and a violent
TB with 'cold abscess' formation
in dorsal spine
A ‘cold abscess’ destroyed several of
Sarah’s vertebrae, causing them to
collapse, bend and fuse to one
another, resulting in severe
curvature of her spine.
Cerebral tuberculoma - TB meningitis.
White granulomatous lesions inside the brain cause
it to become inflamed and swollen. The resultant
increase in intracranial pressure accounts for
Sarah’s severe headaches, nausea and vomiting.
TB of the lungs
This is Miliary tuberculosis - tiny Granulomas,
resembling millet seeds, throughout the lung,
causing the porous tissue to harden. Inflammation
would have caused the surrounding capillaries to
rupture, accounting for Sarah’s violent, blood