1 A patient with chronic kidney disease is least likely to have which of the
following metabolic abnormalities?
2 A patient presents with a K+
of 6.7mmol/L. ECG shows peaked T waves and
absence of P waves. Which of the following is most appropriate in the initial
management of this patient?
B) Dietary restriction of K+
and amino acids
C) Insulin and dextrose
D) Calcium chloride and insulin and dextrose
E) Calcium resonium
3 Which of the following is not routinely considered as part of a renal screen in
the investigation of new-onset renal failure?
B) Renal ultrasound.
C) Caeruloplasmin and serum copper
D) Anti-neutrophil cytoplasmic antibodies
E) Bence–Jones protein
4 A 15-year-old boy is referred to the renal clinic by his GP with a history of
worsening haematuria. His mother has been worried recently that he has
been taking illicit drugs as he has been finding it more difficult to cope at
school and has been falling behind in his schoolwork. He also seems to be
less attentive of late and has become more withdrawn, watching
television on his own with the volume up loud. Which of the following
conditions fits most closely with the clinical history?
)A Alport’s syndrome
)B Anderson–Fabry disease
)C Goodpasture’s syndrome
)D Wegener’s granulomatosis
)E Von Hippel–Lindau syndrome
5 A 30-year-old man presents to hospital complaining that his urine has
been very dark recently. He recently has taken a few days off work with a
very sore throat and coryzal symptoms. Urine dipstick in hospital returns
highly positive for blood and protein. He is admitted for supportive
management and is scheduled for a renal biopsy, which shows mesangial
proliferation with a positive immunofluorescence pattern. What is the
most likely diagnosis?
A) IgA nephropathy
B) Post-streptococcal glomerulonephritis
C) Rapidly progressive glomerulonephritis
D) Membranous glomerulonephritis
E) Henoch-Schoenlein purpura
6 Which one of the following is an indication for renal replacement therapy
B) Hyperkalaemia without ECG changes
D) Cardiogenic pulmonary oedema
E) Chronic kidney disease stage III
7 Which of the following diseases do antibodies against type IV collagen in the
glomerular basement membrane cause?
A) Wegeners granulomatosis
B) Alport’s syndrome
C) Goodpasture’s syndrome
D) Henoch-Schoenlein purpura
E) Scleroderma renal crisis
8 A 71 year old male with chronic kidney disease develops an acutely hot, tender
MCP joint on her left hand. What is the most likely diagnosis?
A) Rheumatoid arthritis
B) Reiter’s syndrome
E) Renal bone osteodystrophy
9 Which one of the following causes of chronic kidney disease is most associated
with a normal haemoglobin concentration?
A) – Goodpasture’s syndrome
B) – Hepatitis C
C) – Hypertension
D) – Polycystic kidney disease
E) – Diabetes mellitus
10 A 35 year old lady with IBS is found to be hypertensive and hypokalaemic
following routine bloods for abdominal pain. She takes only food supplements as
medication. What is the most likely cause?
A) Cushing’s disease
C) 11-beta hydroxysteroid dehydrogenase deficiency
E) Conn’s syndrome