FLUID DISTURBANCES

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FLUID DISTURBANCES

  1. 1. W A T E R I S 5 0 % O F B O D Y W E I G H T I N W O M E N 6 0 % I N M E N w w w . m e d i c i n e m c q . c o m 1 FLUID DISTURBANCES www.medicinemcq.com
  2. 2. Intracellular fluid (ICF) 2 • Largest compartment – 60% • Main cation – potassium • Anions - phosphates and bicarbonate www.medicinemcq.com
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  4. 4. ECF = 40% 4 • Main cation – sodium • Anions - chloride and bicarbonate www.medicinemcq.com www.medicinemcq.com
  5. 5. 5www.medicinemcq.com
  6. 6. 6www.medicinemcq.com
  7. 7. If 1 L of solute-free water is lost from the body, how much fluid is lost by the ICF compartment? 7  Water ICF : ECF = 2:1 ratio  Solute-free water loss  Twofold greater reduction in the ICF compartment than the ECF compartment  Volume loss  ICF = 667 mL  ECF = 333 mL www.medicinemcq.com www.medicinemcq.com
  8. 8. Lose of 1L of iso-osmotic fluid 8  ECF compartment will decrease by 1 L  Na+ is largely restricted to the ECF www.medicinemcq.com
  9. 9. Osmolality and osmolarity 9  Often used interchangeably  Osmolality  Number of solutes per mass of water  Osmolarity  Number of moles of solute in a liter of solution www.medicinemcq.com
  10. 10. Solutes 10  Extracellular and intracellular solutes (or osmoles)  Markedly different  Water  Moves across cell membranes  Distributes between ICF and ECF  Until the osmolality is the same For rest of the slides, visit www.medicinemcq.com > Nephrology www.medicinemcq.com

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