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Honors ~ Cell cycle,mitosis and meiosis 1314

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Honors ~ Cell cycle,mitosis and meiosis 1314

  1. 1. Honors Biology Growth and Development and Cellular Inheritance Introduction
  2. 2. Asexual Reproduction
  3. 3. Sexual Reproduction
  4. 4. Growth and Development
  5. 5. 2n = 20
  6. 6. A chicken has 78 Chromosomes in its Somatic Cells: • How many chromosomes did the chicken inherit from each parent? • How many chromosomes are in each of the chicken’s gametes? • How many chromosomes will be in each somatic cell of the chicken’s offspring? • How many chromosomes are in a “set” • Which came first…chicken or egg?
  7. 7. http://www.youtube.com/watch?v=m73i1Zk8EA0&feature=related
  8. 8. How many chromosomes are shown in this diagram? How many chromatids are shown?
  9. 9. on ati g lon e of e on Z a pic A Compare the number of cells in interphase, prophase, metaphase, anaphase or telophase in these two areas. Explain differences. m ste er i lm
  10. 10. Yeast Life Cycle
  11. 11. Budding Pattern
  12. 12. Yeast Mating Types
  13. 13. Uncontrolled Growth
  14. 14. Angiogenesis
  15. 15. Apoptosis
  16. 16. “Immortal Cells”
  17. 17. Telomerase
  18. 18. Metastasis
  19. 19. Immune System
  20. 20. What would happen if you performed this experiment with cancer cells?
  21. 21. Henrietta Lacks
  22. 22. HeLa cells
  23. 23. Stem Cell Stem Cell video
  24. 24. Stem Cell Sources
  25. 25. Embryonic Stem Cells (ES)
  26. 26. In Vitro Fertilization Louise Brown – Birthday 1978
  27. 27. Nuclear Transfer
  28. 28. Adult Stem Cells
  29. 29. iPS
  30. 30. IPS http://www.youtube.com/watch?v=fGNchPdlaGU&NR=1&feature=fvwp http://www.youtube.com/watch?v=cPvidAvzmx0&feature=related
  31. 31. STAP cells Haruko Obokata.
  32. 32. Controversial therapy.Mitochondrial DNA replacement could help carriers of severe disease have healthy children. G Vogel Science 2014;343:827-828 Published by AAAS
  33. 33. Meiosis Honors Biology
  34. 34. Aneuploidy Article Honors Biology
  35. 35. General Background Questions: • What is the genome, transcriptome and • the proteome? What is aneuploidy?
  36. 36. Experiment Questions: • What was the “conundrum” they identified • in the Introduction? What are the two experimental questions?
  37. 37. Meiosis Question: • Diagram why meiosis with odd ploidy (3N or 5N) would produce aneuploids.
  38. 38. Key Findings • What are key findings from: ab, ef, and gh?
  39. 39. A16 Why is strain A16 a good strain to focus on for experimental question?
  40. 40. ATR1 • What are: C• some XIII, ATR1, 4-NQO, and Strain A16? What is their relationship?
  41. 41. Proteome & Transcriptome: Gene dosage effect or dosage compensation Aneuploidy has global and complex effects on both the transcriptome and proteome levels, and that an increase in stress gene expression is not an obligate . property of aneuploidy strains

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