International Foundation for Functional Gastrointestinal Disorders (IFFGD): International Symposium on Functional Gastrointestinal Disoders
10th INTERNATIONAL SYMPOSIUM ONFUNCTIONALGASTROINTESTINALDISORDERS APRIL 12–14, 2013 The Pfister Hotel Milwaukee, Wisconsin The Pfister Hotel, Milwaukee, WI JOINTLY SPONSORED BY University of Wisconsin School of Medicine and International Foundation for Public Health, Office of Continuing Professional Functional Gastrointestinal Disorders Development in Medicine and Public Health Milwaukee, WI Madison, WI
10 th INTERNATIONAL STATEMENT OF NEED TARGET AUDIENCESYMPOSIUM ON Functional gastrointestinal disorders are among the The 10th International Symposium on FunctionalFUNCTIONAL most common conditions seen by primary care and Gastrointestinal Disorders has been developed toGASTROINTESTINAL specialty practices. Research is rapidly changing the enhance the knowledge and skills of physicians, understanding of the multiple underlying mechanisms psychologists, fellows, physician assistants, nurses, andDISORDERS in these disorders. Patient management and treatment allied health professionals in their care of patients with remains challenging, and there is a lack of effective functional gastrointestinal disorders.April 12–14, 2013 pharmacologic treatments available.The Pfister Hotel ELEMENTS OF COMPETENCEMilwaukee, Wisconsin OBJECTIVES This CME activity has been designed to change learner The sessions will provide participants with competence and performance and focuses on the opportunities to: American Board of Medical Specialties areas of medical knowledge, patient care and procedural skills, and Apply advances in the pathophysiology of interpersonal and communications skills. functional gastrointestinal (GI) and motility disorders Apply newer technologies involved with diagnostic FOR FURTHER INFORMATION assessment of functional GI and motility disorders For registration information please contact: Develop improved clinical skills in the Terese Bailey of the Office of Continuing Professional diagnosis and care of patients with Development in Medicine and Public Health, 2701 functional GI and motility disorders International Lane, #208, Madison, Wisconsin 53704; Develop strategies and skills relating to interview telephone: 608/240-2141; e-mail: email@example.com. technique, communication skills, and patient- For other inquiries please contact: centered care in order to improve patient Elisabeth Vink of the International Foundation for satisfaction, adherence, and clinical outcome Functional Gastrointestinal Disorders (IFFGD), PO Network and share information experiences Box 170864, Milwaukee, Wisconsin 53217; telephone: with other conference participants 414/964-1799; e-mail: firstname.lastname@example.org. Recognize the influence of genetics, early life, and socio-cultural factors on the clinical expression of functional GI and motility disorders Identify the role of neurotransmitters and receptors in the development of clinical symptoms
PLANNING COMMITTEE Nancy J. Norton, President & Founder, Jan Tack, MD, PhD, Professor Lin Chang, MD, Center for Luda B. Diatchenko, MD, PhD, Associate International Foundation for and Head of Clinic, Division of Neurovisceral Sciences and Women’s Professor, Center for NeurosensoryDouglas A. Drossman, MD (Chair), Functional Gastrointestinal Disorders, Gastroenterology, Department of Health Center for Neurobiology Disorders, School of Dentistry, Adjunct Professor of Medicine Milwaukee, WI Internal Medicine, University Hospital of Stress, David Geffen School of University of North Carolina at Chapel and Psychiatry, UNC Center for Henry Parkman, MD, Professor Gasthuisberg, Lueven, Belgium Medicine at UCLA, Los Angeles, CA Hill, Chapel Hill, NC Functional GI and Motility Disorders, of Medicine, Gastroenterology William E. Whitehead, PhD, Professor William D. Chey, MD, AGAF, FACG, Alexander M. Djuricich, MD, Associate University of North Carolina at Section, Temple University Hospital, of Medicine and Adjunct Professor Professor of Medicine; Director, GI Dean for CME; Program Director, Chapel Hill, Chapel Hill, NC Philadelphia, PA of OBGYN, Center for Functional GI Physiology Laboratory; Director, Medicine-Pediatrics Residency;Lin Chang, MD, Center for Max J. Schmulson W., MD, Professor & Motility Disorders, University of Michigan Bowel Control Program, A. Associate Professor of Clinical Neurovisceral Sciences and Women’s of Medicine; Faculty of Medicine, North Carolina at Chapel Hill, Chapel Alfred Taubman Health Care Center, Pediatrics and Clinical Medicine, Health Center for Neurobiology National Autonomous University of Hill, NC University of Michigan Medical Indiana University School of of Stress, David Geffen School of Mexico-UNAM, Laboratory of Liver, John Bryant Wyman, MD, Professor of Center, Ann Arbor, MI Medicine, Indianapolis, IN Medicine at UCLA, Los Angeles, CA Pancreas, and Motility (HIPAM), Medicine, Section of Gastroenterology Giuseppe Chiarioni, MD, Senior Staff, Douglas A. Drossman, MD, AdjunctWilliam D. Chey, MD, AGAF, FACG, Department of Experimental and Hepatology, University of Division of Gastroenterology, University Professor of Medicine and Psychiatry, Professor of Medicine; Director, GI Medicine, General Hospital of Wisconsin School of Medicine and of Verona, Verona, Italy; Associate UNC Center for Functional GI and Physiology Laboratory; Director, Mexico, Mexico City, Mexico Public Health, Madison, WI Professor of Medicine, Division of Motility Disorders, University of Michigan Bowel Control Program, A. Keith A. Sharkey, PhD, Professor and Gastroenterology and Hepatology, North Carolina at Chapel Hill, Chapel Alfred Taubman Health Care Center, AI-HS Medical Scientist, Department FACULTY Center for Functional & GI Motility Hill, NC University of Michigan Medical of Physiology & Pharmacology; Disorders, University of North Carolina Gianrico Farrugia, MD, Director, Center Center, Ann Arbor, MI Deputy Director, Hotchkiss Brain Fernando Azpiroz, MD, PhD, at Chapel Hill, Chapel Hill, NC for Individualized Medicine, Division ofCarlo Di Lorenzo, MD, Chief, Division Institute, University of Calgary, Department of Digestive Diseases, Sheila E. Crowe, MD, FRCPC, FACP, Gastroenterology, Hepatology, Internal of Pediatric Gastroenterology, Calgary, AB, Canada University General Vall d’Hebron, FACG, AGAF, Professor of Medicine; Medicine, Department of Physiology Nationwide Children’s Hospital; Barcelona, Spain Director of Research, Division of and Biomedical Engineering, Mayo Magnus Simrén, MD, PhD, Professor, Professor of Clinical Pediatrics, The Department of Internal Medicine, Giovanni Barbara, MD, Department Gastroenterology, Department of Clinic, Rochester, MN Ohio State University, Columbus, OH Institute of Medicine, Sahlgrenska of Clinical Medicine, University Medicine, University of California, Ronnie Fass, MD, Professor ofRonnie Fass, MD, Professor of Academy, University of Gothenburg, of Bologna; St. Orsola-Malpighi San Diego, La Jolla, CA Medicine, University of Arizona; Medicine, University of Arizona; Gothenburg, Sweden Hospital, Bologna, Italy Willem M. de Vos, PhD, Professor of Chief of Gastroenterology and Head, Chief of Gastroenterology and Head, Ami Sperber, MD, MSPH, Tel-Aviv Elizabeth Beckett, PhD, Lecturer, Microbiology, Academy Professor Neuroenteric Clinical Research Neuroenteric Clinical Research Medical Center; Emeritus Professor of Discipline of Physiology, School of of the Finnish Academy of Sciences, Group, Tucson, AZ Group, Tucson, AZ Medicine, Ben-Gurion University of Medical Sciences, The University of Laboratory of Microbiology, Christophe Faure, MD, ProfessorJohn E. Kellow, MD, Head, Discipline the Negev, Beer-Sheva, Israel Adelaide, Adelaide, Australia Wageningen University, Wageningen, of Pediatrics, Division of of Medicine, Sydney Medical Adil E. Bharucha, MD, Professor The Netherlands Gastroenterology and Nutrition, CHU Brennan Spiegel, MD, MSHS, FACG, School-Northern, University of AGAF, Associate Professor of of Medicine, Division of Inge Depoortere, PhD, Translational Sainte-Justine, Montreal, QC, Canada Sydney; Director, Gastrointestinal Medicine, VA Greater Los Angeles Gastroenterology and Hepatology, Research Center for Gastrointestinal Dee E. Fenner, MD, Furlong Professor Investigation Unit, Royal North Shore Healthcare System, David Geffen Mayo Clinic College of Medicine, Disorders, Catholic University of of Women’s Health; Director Hospital, Sydney, Australia School of Medicine at UCLA, UCLA Rochester, MN Leuven, Leuven, Belgium of Gynecology, Department ofGary Mawe, PhD, Professor, School of Public Health; Director, L. Ashley Blackshaw, PhD, Carlo Di Lorenzo, MD, Chief, Division Obstetrics and Gynecology, University Department of Anatomy and UCLA GI Fellowship Training Neurogastroenterology Group, of Pediatric Gastroenterology, of Michigan Hospital and Health Neurobiology, University of Vermont, Program; Director, UCLA/VA Bluzard Institute, Queen Mary Nationwide Children’s Hospital; Systems, Ann Arbor, MI Burlington, VT Center for Outcomes Research and University of London, London, Professor of Clinical Pediatrics, The Education (CORE), Los Angeles, CA England, United Kingdom Ohio State University, Columbus, OH
Carlos Francisconi, MD, PhD, Associate Lesley A. Houghton, PhD, CBiol, FSB, Peter J. Kahrilas, MD, Professor Ann C. Lowry, MD, Clinical Professor Nancy J. Norton, President & Founder, Professor of Medicine, The Federal FACG, AGAF, Professor of Medicine, of Medicine, Division of of Surgery, Division of Colon and International Foundation for University of Rio Grande do Sul, College of Medicine, Mayo Clinic; Gastroenterology, Northwestern Rectal Surgery, Department of Functional Gastrointestinal Disorders, Clinic Hospital of Porto Alegre, Porto Director of Research, Gastroenterology University Feinberg School of Surgery, University of Minnesota, Milwaukee, WI Alegre, RS, Brazil and Hepatology, Division of Medicine, Chicago, IL Minneapolis, MN Samuel Nurko, MD, MPH, AssociateShin Fukudo, MD, PhD, Professor, Gastroenterology and Hepatology, Laurie Keefer, PhD, Associate Professor Gary Mawe, PhD, Professor, Department Professor of Pediatrics; Director, Department of Behavioral Medicine, Mayo Clinic, Jacksonville, FL; Honorary of Medicine; Director, Center for of Anatomy and Neurobiology, Center for Motility and Functional Tohoku University Graduate School of Professor of Neurogastroenterology, Psychosocial Research in GI, Division University of Vermont, Burlington, VT Gastrointestinal Disorders, Children’s Medicine, Aoba, Sendai, Japan Translational Medicine, University of Gastroenterology, Northwestern Hospital Boston, Harvard Medical Emeran A. Mayer, MD, Director, of Manchester, Manchester, England, University Feinberg School of School, Boston, MAMichael D. Gershon, MD, Professor, Oppenheimer Family Center for United Kingdom; Honorary Medicine, Chicago, IL Department of Pathology and Cell Neurobiology of Stress; Co-Director, Kevin W. Olden, MD, Vice Chairman Consultant, University Hospital of Biology, Columbia University, College of John E. Kellow, MD, Head, Discipline CURE Digestive Diseases Research of Medicine, St. Joseph’s Hospital South Manchester NHS Foundation Physicians and Surgeons, New York, NY of Medicine, Sydney Medical Center, Division of Digestive Diseases, and Medical Center; Professor of Trust, South Manchester, England,Albena Halpert, MD, Assistant School-Northern, University of David Geffen School of Medicine at Medicine and Psychiatry, Creighton United Kingdom Professor of Medicine, Department of Sydney; Director, Gastrointestinal UCLA, Los Angeles, CA University School of Medicine, Tracy L. Hull, MD, Professor of Surgery, Investigation Unit, Royal North Shore Phoenix, AZ Gastroenterology, Boston University Hayat Mousa, MD, AGAF, Medical Holder of the Shafran Family Hospital, Sydney, Australia School of Medicine, Boston, MA Director, Center for Advanced Research Tamas Ordog, MD, SAC and Director, Charitable Trust Endowed Chair,Frank A. Hamilton, MD, MPH, Chief of J. S. Labus, PhD, Adjunct Assistant in Neuromuscular Gastrointestinal Gastroenterology Research Unit, Department of Colon and Rectal the Digestive Disease Branch, Division Professor, Semel Institute (NPI), Disorders (C.A.R.I.N.G); Director, Division of Gastroenterology and Surgery, Digestive Disease Institute, of Digestive Diseases & Nutrition, Oppenheimer Family Center for Fellowship in the Advanced Training in Hepatology; Director, Epigenomics Cleveland Clinic Foundation, NIH/NIDDK, Bethesda, MD Neurobiology of Stress, UCLA Division Gastrointestinal Motility and Functional Translational Program, Center for Cleveland, OH of Digestive Diseases, Los Angeles, CA Disorders; Professor in Clinical Individualized Medicine; AssociateWilliam Hasler, MD, Professor of Internal A. Pali Hungin, MD, Head of School; Jeffrey M. Lackner, PsyD, Associate Pediatrics, Ohio State University College Professor, Physiology and Biomedical Medicine, Division of Gastroenterology, Dean of Medicine in Medicine and Professor, Department of Medicine, of Medicine, Nationwide Children’s Engineering and Enteric Neuroscience University of Michigan Medical Center, Health, School of Medicine and University at Buffalo School of Hospital, Division of Gastroenterology, Program, College of Medicine, Mayo Ann Arbor, MI Health, Durham University, Stockton- Medicine, SUNY, Buffalo, NY Columbus, OH Clinic, Rochester, MNRuyi He, MD, Medical Team Leader, on-Tees, England, United Kingdom Brian E. Lacy, MD, PhD, Director, Michel Neunlist, PhD, Head of Inserm John E. Pandolfino, MD, Division of Gastroenterology and Paul Hyman, MD, Chief, Pediatric Gastrointestinal Motility Lab, Unit 913, Neuropathies of the Enteric Associate Professor, Division of Inborn Error Products, Center for Drug Gastroenterology, Children’s Hospital Division of Gastroenterology and Nervous System and Digestive Gastroenterology, Northwestern Evaluation and Research, Food and Drug at New Orleans, New Orleans, LA Hepatology, Dartmouth-Hitchcock Diseases, Institute of Digestive University Feinberg School of Administration, Silver Spring, MD Mutsuhiro Ikuma, MD, PhD, Senior Medical Center, Lebanon, NH Diseases, Nantes University Hospital, Medicine, Chicago, ILSteve Heymen, PhD, Associate Professor Medical Reviewer, Pharmaceutical and Nantes, France Anthony J. Lembo, MD, Associate Henry Parkman, MD, Professor of Medicine, of Medicine; Director of Biofeedback Medical Devices Agency, Tokyo, Japan Professor of Medicine, Harvard Beate Niesler, PhD, Group Leader, Gastroenterology Section, Temple Services, Center for Functional GI Stephen James, MD, Director, Division Medical School, Beth Israel Deaconess Neurogastroenterology and Psychiatric University Hospital, Philadelphia, PA and Motility Disorders, University of of Digestive Diseases & Nutrition, Medical Center, Boston, MA Disorders; Head of nCounter Core P. Jay Pasricha, MD, Director, North Carolina at Chapel Hill, Chapel NIDDK-NIH, Bethesda, MD Facility, University of Heidelberg, Johns Hopkins Center for Hill, NC Rona L. Levy, MSW, PhD, MPH, Michael P. Jones, PhD, Associate Professor, Institute of Human Genetics, Neurogastroenterology, Division ofIkuo Hirano, MD, Professor of Medicine; Professor and Director, Behavioral Department of Psychology, Macquarie Department of Human Molecular Gastroenterology and Hepatology, Fellowship Program Director, Medicine Research Group; Professor, University, Sydney, Australia Genetics, Heidelberg, Germany Johns Hopkins University School of Northwestern University Feinberg School of Social Work; Adjunct Professor of Medicine and Psychology, Medicine, Baltimore, MD School of Medicine, Chicago, IL University of Washington, Seattle, WA
Mark Pimentel, MD, FRCPC, Director, Miguel Saps, MD, Director of Magnus Simrén, MD, PhD, Professor, Nikhil Thapar, BM, MRCP, MRCPCH, Lukas Van Oudenhove, MD, PhD, GI Motility Program, Cedars-Sinai Gastrointestinal Motility and Department of Internal Medicine, PhD, Senior Lecturer in Pediatric Consultant Psychiatrist; FWO Medical Center, Los Angeles, CA Functional Bowel Disorders Institute of Medicine, Sahlgrenska Gastroenterology, Gastroenterology Postdoctoral Research Fellow,Charlene M. Prather, MD, MPH, Program and Attending Physician, Academy, University of Gothenburg, and Neural Development Units, Translational Research Center for Professor of Internal Medicine, Gastroenterology, Ann & Robert H. Gothenburg, Sweden University College London Institute of Gastrointestinal Disorders (TARGID), Division of Gastroenterology and Lurie Children’s Hospital of Chicago; Manu Sood, MD, Department of Child Health, Honorary Consultant in University of Leuven, University Hepatology, St. Louis University Assistant Professor of Pediatrics, Pediatric Gastroenterology, Medical Pediatric Gastroenterology, Division of Hospital Gasthuisberg, Leuven, Belgium School of Medicine, St. Louis, MO Northwestern University Feinberg College of Wisconsin, Milwaukee, WI Neurogastroenterology and Motility, Miranda van Tilburg, PhD, Assistant School of Medicine, Chicago, IL Ami Sperber, MD, MSPH, Tel-Aviv Department of Gastroenterology, Professor of Medicine, Center forEamonn Quigley, MD, Professor of Elmer Schabel, MD, Clinical Assessor, Medical Center; Emeritus Professor of Great Ormond Street Hospital; Functional GI and Motility Disorders, Medicine and Human Physiology; European Medicines Agency; Medicine, Ben-Gurion University of Co-director, Academy of Pediatric University of North Carolina at Chapel Principal Investigator, Alimentary Scientific Advice Working Party, the Negev, Beer-Sheva, Israel Gastroenterology, London, England, Hill, Chapel Hill, NC Pharmabiotic Center, Department of Federal Institute for Drugs and United Kingdom Medicine, University College Cork, Brennan Spiegel, MD, MSHS, FACG, Stephen J. Vanner, MD, MSc, FRCPC, Cork, Ireland Medical Devices, Bonn, Germany AGAF, Associate Professor of Kirsten Tillisch, MD, Assistant Professor Director, Gastrointestinal Diseases Max J. Schmulson W., MD, Professor Medicine, VA Greater Los Angeles of Medicine, Division of Digestive Research Unit, Queen’s University,Satish S. C. Rao, MD, PhD, FRCP, of Medicine; Faculty of Medicine, Healthcare System, David Geffen Diseases, The Oppenheimer Family Kingston, ON, Canada FACG, AGAF, Professor of Medicine; National Autonomous University of School of Medicine at UCLA, UCLA Center for Neurobiology of Stress, Chief, Section of Gastroenterology/ Elena Verdú, MD, PhD, Associate Professor, Mexico-UNAM, Laboratory of Liver, School of Public Health; Director, David Geffen School of Medicine, Hepatology; Director, Digestive Department of Medicine; Director, Pancreas, and Motility (HIPAM), UCLA GI Fellowship Training UCLA, Los Angeles, CA Health Center, Georgia Health Axenic Gnotobiotic Unit, McMaster Sciences University, Medical College Department of Experimental Program; Director, UCLA/VA Irene Tracey, BA, MA (Oxon), PhD, University, Hamilton, ON, Canada of Georgia, Augusta, GA Medicine, General Hospital of Center for Outcomes Research and FRCA, Nuffield Professor of Arnold Wald, MD, Professor of Mexico, Mexico City, Mexico Education (CORE), Los Angeles, CA Anesthetic Science; Director, OxfordHelen Raybould, PhD, Professor and Medicine, Section of Gastroenterology Reza Shaker, MD, Joseph E. Geenen Robin Spiller, MD, FRCP, Professor of Center for FMRI of Brain; Head, Department Chair, Department & Hepatology, University of Wisconsin Professor & Chief, Division of Gastroenterology; Head of Division Nuffield Division Anesthetics, of Anatomy, Physiology, and School of Medicine and Public Health, Gastroenterology and Hepatology; of Gastroenterology; Lead Director Nuffield Department of Clinical Cell Biology, UC Davis, School of Madison, WI Senior Associate Dean and Director, of NIHR Biomedical Research Unit, Neurosciences, University of Oxford, Veterinary Medicine, Davis, CA William E. Whitehead, PhD, Professor Clinical and Translational Science Nottingham Digestive Diseases Center, Oxford, England, United KingdomRichard J. Saad, MD, MS, Assistant of Medicine and Adjunct Professor of Institute, Medical College of University Hospital, Nottingham, Nimish Vakil, MD, FACP, FACG, Professor of Medicine, Division OBGYN, Center for Functional GI & Wisconsin, Milwaukee, WI England, United Kingdom AGAF, FASGE, Clinical Professor of of Gastroenterology, Department Motility Disorders, University of North Keith A. Sharkey, PhD, Professor and Jan Tack, MD, PhD, Professor Medicine, University of Wisconsin of Internal Medicine, University Carolina at Chapel Hill, Chapel Hill, NC AI-HS Medical Scientist, Department and Head of Clinic, Division of School of Medicine and Public of Michigan Hospital and Health Jackie D. Wood, MSc, PhD, AGAF, of Physiology & Pharmacology; Gastroenterology, Department of Health, Madison, WI Systems, Ann Arbor, MI Professor, Department of Physiology & Deputy Director, Hotchkiss Brain Internal Medicine, University Hospital René M. van den Wijngaard, PhD,Yuri Saito, MD, MPH, Assistant Gasthuisberg, Lueven, Belgium Cell Biology, The Ohio State University Institute, University of Calgary, Scientific Staff Member, Tytgat Professor of Medicine, Division of College of Medicine, Columbus, OH Calgary, AB, Canada Yvette Taché, PhD, Professor of Institute for Liver and Intestinal Gastroenterology & Hepatology, Katie Zarzar, Director of Strategic Accounts Robert J. Shulman, MD, Professor Medicine, David Geffen School of Research, Academic Medical Center, Division of Epidemiology, Mayo - Linguistic Validation, TransPerfect, of Pediatrics, Baylor College of Medicine at UCLA; Director, CURE: Amsterdam, The Netherlands Clinic, Rochester, MN RTP, NC Medicine, Children’s Nutrition Digestive Diseases Research Center -Kenton M. Sanders, PhD, Professor and Animal Core; Co-Director, Center for Research Center, Texas Children’s Chair, Department of Physiology and Neurobiology of Stress & Women’s Hospital, Houston, TX Cell Biology, University of Nevada Health, VA Greater Los Angeles School of Medicine, Reno, NV Healthcare System, Los Angeles, CA
SCHEDULE • 2013FRIDAY, APRIL 12 1:55 Neurogenesis in the Adult Enteric Nervous System S4: Gastric Motility Disorders - Michael D. Gershon, MD Chair: Henry Parkman, MDAM 2:15 Visceral Hypersensitivity • Gastroparesis - P. Jay Pasricha, MD7:00 Registration and Breakfast - Stephen J. Vanner, MD, MSc, FRCPC • Functional Dyspepsia - Jan Tack, MD, PhD8:00 Greetings - Nancy J. Norton & Stephen James, MD 2:35 Pain, Emotion, and Interoception • Dumping Syndrome - William Hasler, MDAM Plenary - Irene Tracey, BA, MA (Oxon), PhD, FRCA • Rumination Syndrome: How to Distinguish it 2:55 Discussion From Functional Vomiting - Ronnie Fass, MDClinical Approach8:20 Moderator: Douglas A. Drossman, MD 3:15 Refreshment Break S5: Opioid and Narcotic Bowel Chair: Douglas A. Drossman, MD8:25 Global Epidemiology PM Mini Symposia • Mechanisms of Opioid Bowel - Elizabeth Beckett, PhD - Eamonn Quigley, MD 3:30 - 5:00 (1.5 hours) • Treatments of Opioid Bowel - Lin Chang, MD8:45 What’s New in Pathophysiology of FGIDs S1: Neural Regulation of Human Gut • Narcotic Bowel - Douglas A. Drossman, MD - John E. Kellow, MD Function and Sensation9:05 Integrated Approach to FGIDs Chair: Gary Mawe, PhD 5:00 Adjourn - Douglas A. Drossman, MD • Enteric Nervous System Stem Cells Derived From 5:30 Reception, Awards Program, and Dinner9:50 Discussion Human Gut Mucosa10:15 Refreshment Break - Nikhil Thapar, BM, MRCP, MRCPCH, PhD SATURDAY, APRIL 13 • Neuronal and Glial Signaling in the Human GutHot Topics AM - Michel Neunlist, PhD10:45 Moderator: William D. Chey, MD, AGAF, FACG • Functional Brain-Gut Imaging in Health and 7:00 Breakfast10:50 What is the Link Between the Gut Microbiome and Functional Bowel Disorders - Emeran A. Mayer, MD AM Plenary FGIDs - Willem M. de Vos, PhD S2: Treatment of Pain Predominant State-of-the-Art on What’s New in Pediatric FGIDs11:20 Food and GI Symptoms: Effects on Permeability, Pediatric FGIDs 8:00 Moderator: Paul Hyman, MD Immunology, Motility, and Sensation Chair: Carlo Di Lorenzo, MD 8:05 What’s New in Pathophysiology of Pain - Elena Verdú, MD, PhD • Pharmacological Treatments - Miguel Saps, MD Predominant FGIDs - Christophe Faure, MD11:45 Manipulating the Gut Microbiome as a Treatment • Behavioral Treatments - Rona L. Levy, MSW, PhD, MPH • Early Life Events: What Are The Implications For 8:25 What’s New in Pathophysiology of Defecation Strategy for FGIDs - Magnus Simrén, MD, PhD Children With FGIDs? - Miranda van Tilburg, PhD Disorders - Samuel Nurko, MD, MPH12:10 Discussion • Time for Gastric and Colonic Pacing? 8:45 What’s New in Diagnosis of Upper GI Tract FGIDs12:30 Lunch - Hayat Mousa, MD, AGAF - Manu Sood, MDPM Plenary S3: Genetics 9:05 What’s New in Diagnosis of Defecation DisordersNeurogenesis, Neuroplasticity, and FGIDs Chair: Yuri Saito, MD, MPH - Carlo Di Lorenzo, MD1:30 Co-Moderators: Gary Mawe, PhD & Keith A. Sharkey, PhD • State-of-the-Art: How to Set Up a Genetic FGID 9:25 Discussion Study - Beate Niesler, PhD 9:40 Refreshment Break1:35 Emerging Topics in Neurogastroenterology and • Basic Foundations - Yuri Saito, MD, MPH Motility - Keith A. Sharkey, PhD • Future in Research - Luda B. Diatchenko, MD, PhD
SCHEDULE • 2013AM Mini Symposia S10: The Rome Working Group, Food & FGIDs B2: Anorectal Dysfunction Chair: Jan Tack, MD, PhD Coordinator: Adil E. Bharucha, MD10:00 - 12:30 (2.5 hours) • Nutrient Sensing Mechanisms - Helen Raybould, PhD • Pelvic Floor Dyssynergia - Richard J. Saad, MD, MSS6: Novel Biomarkers Chair: Satish S. C. Rao, MD, PhD, FRCP, FACG, AGAF • Food and GI Function: How Does Food Change • Levator Ani Pain and Proctalgia Fugax GI Function in Man? - Fernando Azpiroz, MD, PhD - Adil E. Bharucha, MD • Gastric Emptying and Colonic Transit • Dietary Factors and Upper GI Symptoms: What is • Hemorrhoids and Fissures - Tracy L. Hull, MD - Satish S. C. Rao, MD, PhD, FRCP, FACG, AGAF Known, What is Proven? - Jan Tack, MD, PhD B3: Brain/Gut Modulation of GI Symptoms • Blood, Urine, and Stool - Michael P. Jones, PhD • Dietary Factors and Lower GI Symptoms Coordinator: Kirsten Tillisch, MD • Psychosocial - Lukas Van Oudenhove, MD, PhD - William D. Chey, MD, AGAF, FACG • Objective Measure in Volume ChangesS7: Intestinal Permeability and • Gluten Sensitivity and its Role in - J. S. Labus, PhD Visceral Hypersensitivity Functional GI Symptoms • Clinical Implications of Brain Imaging Chair: Yvette Taché, PhD - Sheila E. Crowe, MD, FRCPC, FACP, FACG, AGAF - Lukas Van Oudenhove, MD, PhD • Differences/Interaction Between Nutrient S11: Sorting Out Treatments for Constipation • Drug Studies: Brain Activation Patterns With Sensing and Pain Processing Afferents Chair: Magnus Simrén, MD, PhD Relation to Drugs - Kirsten Tillisch, MD - L. Ashley Blackshaw, PhD • IBS-C v. Chronic Constipation v. Dyssynergia: Is B4: Neuromuscular Function and Dysfunction • Primary Sensory Neurons There Really a Difference? - William E. Whitehead, PhD Coordinator: Kenton M. Sanders, PhD - Stephen J. Vanner, MD, MSc, FRCPC • Biofeedback - Giuseppe Chiarioni, MD • Central Processing of Pain • Interstitial Cells of Cajal in Health and Disease • Emerging Therapies - Magnus Simrén, MD, PhD - Gianrico Farrugia, MD - Irene Tracey, BA, MA (Oxon), PhD, FRCA • Surgery - Ann C. Lowry, MD • Epigenetic Regulation of Smooth Muscle Growth • Immune Cells, Permeability, and Visceral • Constipation in an Aged Population Hypersensitivity - René M. van den Wijngaard, PhD and Function in the Gut - Tamas Ordog, MD - Charlene M. Prather, MD, MPH • New Insights Into Intestinal Permeability - Clinical • Fibroblast-like Cells and Purinergic Implications in IBS - Giovanni Barbara, MD 12:30 Lunch Neuromuscular Signaling - Kenton M. Sanders, PhDS8: Bloating, Distension, and Gas PM Workshops B5: International Drug Development Chair: Max J. Schmulson W., MD 2:00 - 5:00 WORKSHOP (3 hours) Coordinator: Robin Spiller, MD, FRCP • Mechanisms - Lesley Houghton, PhD, CBiol, FSB, FACG, AGAF A1: Interview Techniques and • Japan - Shin Fukudo, MD, PhD • Bacterial Flora - Mark Pimentel, MD, FRCPC • Europe - Robin Spiller, MD, FRCP Communication Skills • Bloating Treatments - Max J. Schmulson W., MD Coordinator: Douglas A. Drossman, MD; • Latin America - Carlos Francisconi, MD, PhD • Impact of the Symptoms and Clinical Value of Albena Halpert, MD • United States - Anthony J. Lembo, MD Treatments - Eamonn Quigley, MD 2:00 - 3:30 WORKSHOPS (1.5 Hours) 3:30 Refreshment Break • Psychological Aspects - Laurie Keefer, PhD B1: Clinical Pearls for the ClinicianS9: Challenging Cases Coordinator: Lin Chang, MD Chair: Arnold Wald, MD • Psychological Pearls - Jeffrey M. Lackner, PsyD • Dyspepsia and SMA - Brian E. Lacy, MD, PhD • Diagnostic Pearls - William D. Chey, MD, AGAF, FACG • Polysymptomatic FGIDs - Albena Halpert, MD • Physiology Pearls - Henry Parkman, MD • Refractory Heartburn - Ronnie Fass, MD • Treatment Pearls - Lin Chang, MD • Refractory Lower Bowel - Arnold Wald, MD
SCHEDULE • 20134:00 - 5:30 WORKSHOPS (1.5 Hours) • NIDDK Public Awareness Campaign S14: Pediatric Research - Frank A. Hamilton, MD, MPH Chair: Carlo Di Lorenzo, MDC1: FGIDs in the Technological Era Coordinator: Ami Sperber, MD, MSPH • Pathophysiology and Diagnostic Evaluation • Gut Microbe Signatures in Children with IBS - Adil E. Bharucha, MD - Robert J. Shulman, MD • Social Media and Medicine • Overlap of Fecal Incontinence with Urinary - Alexander M. Djuricich, MD • Role of Serotonin Signaling in Children with Incontinence and Other Pelvic Floor Disorders Functional Abdominal Pain - Christophe Faure, MD • Tools for Global Research: Linguistic Validation - Dee E. Fenner, MD and ePRO - Katie Zarzar • Working Together For a Better Understanding • Conservative Management and Biofeedback of Childhood FGIDs: Lessons from the Digestive • Assessing and Diagnosing IBS as a Global - Steve Heymen, PhD Phenomenon - How Can the Technological Health Alliance Children’s Research Network • Surgical Treatments, Including: SNS, TOPAS Sling, - Carlo Di Lorenzo, MD Era Help? - Ami Sperber, MD, MSPH and Bulking Agents - Ann C. Lowry, MD • Time to Treat the Parents to Make the ChildrenC2: Esophageal Disorders 5:30 Adjourn - Dinner on your own Better - Rona L. Levy, MSW, PhD, MPH Coordinator: Ronnie Fass, MD S15: Nutrients, Emotion, and Food Intake • Globus - Peter J. Kahrilas, MD SUNDAY, APRIL 14 Chair: Emeran A. Mayer, MD • Esophageal Dysmotility - Reza Shaker, MD 7:00 Breakfast • Fat Signaling and Emotion • Refractory GERD - Ronnie Fass, MD - Lukas Van Oudenhove, MD, PhD • Eosinophilic Esophagitis - Ikuo Hirano, MD AM Mini Symposia • Bitter Taste Receptors, Food Intake, and GI MotorC3: Serotonin - New Insights in Signaling and 8:00 - 10:30 (2.5 hours) Function - Inge Depoortere, PhD Therapeutic Implications S12: Clinical Trial Design and • Nutrient Signaling and Vagal Control of Gut Co-Coordinators: Keith A. Sharkey, PhD and Function - Helen Raybould, PhD Outcome Measurement Jackie D. Wood, MSc, PhD, AGAF • Nutrient Signaling and Pain Sensation Chair: William D. Chey, MD, AGAF, FACG • Serotonin Signaling in the Gut - Michael D. Gershon, MD - L. Ashley Blackshaw, PhD • Clinical Trial Design Issues for FGIDs - Ruyi He, MD • New Insights Into The Prokinetic and • GERD - Brennan Spiegel, MD, MSHS, FACG, AGAF 10:30 Refreshment Break Antinociceptive Actions of 5-HT4 Receptor • Functional Dyspepsia - Jan Tack, MD, PhD AM Plenary Activation - Gary Mawe, PhD • Gastroparesis - Henry Parkman, MD • Translational Studies of The Role of 5-HT in Clinical Application • IBS - Lin Chang, MD Visceral Pain and GI Motility - Jan Tack, MD, PhD • The Regulatory Issues Around FGIDs in Europe 10:45 Moderator: Lin Chang, MDC4: Update on the Diagnosis and Treatment of - Elmer Shabel, MD 10:50 Maximizing the Physician/Patient Relationship Less Common FGIDs • The Regulatory Issues Around FGIDs in Japan - Albena Halpert, MD Coordinator: John E. Kellow, MD - Mutsuhiro Ikuma, MD, PhD 11:10 Central Pharmacological Treatments for FGIDs • Noncardiac Chest Pain - John E. Pandolfino, MD S13: Rome - Douglas A. Drossman, MD • Chronic Idiopathic Nausea and Functional Chair: Douglas A. Drossman, MD 11:30 New and Emerging Treatments of the Gut Vomiting - Kevin W. Olden, MD • What’s New in Rome IV - Douglas A. Drossman, MD - William D. Chey, MD, AGAF, FACG • Functional Sphincter of Oddi Disorder • Multi-Dimensional - Douglas A. Drossman, MD 11:50 Behavioral Treatments for FGIDs - Laurie Keefer, PhD - Nimish Vakil, MD, FACP, FACG, AGAF, FASGE • Primary Care - A. Pali Hungin, MD • Question Validation - William E. Whitehead, PhD 12:10 DiscussionC5: Fecal Incontinence Coordinator: William E. Whitehead, PhD • Multi-National - Ami Sperber, MD, MSPH 12:25 Closing Remarks - Nancy J. Norton & Douglas A. Drossman, MD • Definitions, Epidemiology, and Quality of Life Impact - William E. Whitehead, PhD 12:40 Adjourn - Box lunch to go
REGISTRATION FORM #4006; AME-GAST10 INTERNATIONAL SYMPOSIUM ON FUNCTIONAL GASTROINTESTINAL DISORDERS THApril 12 - 14, 2013Please Print in BLOCK LettersSTEP 1. Participant Information:Name First MI LastProfessional Degree (for credit and name badge) MD; DO; PhD; RN; PA; Other, please specifyCompany Name Dept. Name or Mail Code Work Address City, State, Zip, Country Day Phone FAX E-mail STEP 2. Confirmation: Work Address (as provided in Step 1) or Home AddressHome Address City, State, Zip, Country
STEP 3. Registration Fees: STEP 4. Workshop & Mini Symposium Registration: WORKSHOP & MINI SYMPOSIA REGISTRATION: SATURDAY, APRIL 13 – PM WORKSHOPS $600 MD/DO/PhD Fee Please check the sessions you would like to attend. Please choose one 3 hour workshop – OR – $400 Fellow/RN/Resident/PA/Other(s) Fee Requests will be honored on a first-come, first-served two 1.5 hour workshops. basis.TOTAL FEE REMITTED: _____________ 3 hour workshop: 2:00 pm - 5:00 pm FRIDAY, APRIL 12 – PM MINI SYMPOSIA A1. Interview Techniques and Communication Skills____PO or check enclosed (payable to University of Wisconsin) Please choose one 1.5 hour session. 1.5 hour workshops: 2:00 pm - 3:30 pm B1. Clinical Pearls for the Clinician____Please bill my company Mini Symposia: 3:30 pm – 5:00 pm (1.5 hours) B2. Anorectal Dysfunction S1. Neural Regulation of Human Gut Function B3. Brain/Gut Modulation of GI Symptoms____Credit Card: and Sensation B4. Neuromuscular Function and Dysfunction MasterCard S2. Treatment of Pain Predominant Pediatric FGIDs B5. International Drug Development VISA S3. Genetics American Express S4. Gastric Motility Disorders 1.5 hour workshops: 4:00 pm - 5:30 pm S5. Opioid and Narcotic Bowel C1. FGIDs in the Technological EraCardholder’s Name C2. Esophageal Disorders C3. Serotonin - New Insights in Signaling and SATURDAY, APRIL 13 – AM MINI SYMPOSIA Therapeutic Implications Please choose one 2.5 hour session. C4. Update on the Diagnosis and Treatment of LessCard Number Common FGIDs Mini Symposia: 10:00 am - 12:30 pm (2.5 hours) C5. Fecal Incontinence S6. Novel Biomarkers S7. Intestinal Permeability and Visceral Hypersensitivity SUNDAY, APRIL 14 – AM MINI SYMPOSIAExpiration Date S8. Bloating, Distension, and Gas Please choose one 2.5 hour session. S9. Challenging Cases S10. The Rome Working Group, Food & FGIDs Mini Symposia: 8:00 am - 10:30 am (2.5 hours) S11. Sorting Out Treatments for Constipation S12. Clinical Trial Design and Outcome Measurement S13. Rome S14. Pediatric Research S15. Nutrients, Emotion, and Food Intake STEP 5. Please return your payment with this form to: CME Specialist, The Pyle Center, Department 101, 702 Langdon Street, Madison, WI 53706 or Fax 1-800/741-7416 (in Madison Fax 265-3163). The University of Wisconsin provides equal opportunities in employment and programming, including Title IX requirement. The University of Wisconsin School of Medicine and Public Health fully complies with the legal requirements of the ADA and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please notify Terese Bailey in order to receive service. Please call: 608/240-2141.
GENERAL INFORMATIONDates: April 12 - 14, 2013 Saturday, April 13 information or pay by MasterCard, Credit Designation StatementPlace: The Pfister Hotel 7:00 - 8:05 am; 9:25 - 10:00 am; VISA, or American Express. The University of Wisconsin School of424 E. Wisconsin Avenue 12:15 - 2:00 pm; 3:15 - 4:00 pm By Fax: 1-800/741-7416 Medicine and Public Health designatesMilwaukee, WI 53202 For an Exhibitor Prospectus, please (in Madison fax 265-3163). this educational activity for aPhone: 414/273-8222 contact Elisabeth Vink at maximum of 18.75 AMA PRA Category 1 Download a one page pdf of the email@example.com or 414/964-1799. Credits™. Physicians should only claimToll-free (USA): 800/558-8222 registration for faxing or mailing at: credit commensurate with the extentFax: 414/273-5025 www.ocpd.wisc.edu/course_catalog HOUSING of their participation in the activity. www.iffgd.org/symposiumWebsite: www.thepfisterhotel.com A block of rooms has been reserved at The Pfister Hotel, 424 E. Wisconsin Continuing Education Units CONFIRMATIONSSYMPOSIUM FEE Avenue, Milwaukee, WI 53202; All registrations are confirmed in The University of Wisconsin-Madison,The symposium fee of $600 for telephone: 414/273-8222. The special writing. If you do not receive a as a member of the Universityphysicians and psychologists; $400 for symposium rates are: confirmation, please call 608/262-1397. Continuing Education Associationfellows, nurses, residents, physicians’ (UCEA), authorizes this program for Single: $184/night plus taxassistants, and others, includes the CONFERENCE ATTIRE 1.875 continuing education unitscost of tuition, materials, breakfasts, Double: $204/night plus tax To ensure your comfort in the (CEUs) or 18.75 hours.refreshment breaks, lunches, The Pfister will release the block of conference rooms, please bring a Policy on Faculty and Sponsorone dinner, and a nonrefundable rooms to the general public on March sweater or jacket to accommodate Disclosure It is the policy of theregistration fee of $50. Should you 20, 2013. Please call or write the temperature variations. University of Wisconsin School ofcancel your registration up to 72 hours Hotel directly for your reservation and CREDIT Medicine and Public Health that theprior to the symposium; you will be mention “10th International Symposium faculty, authors, planners, and otherrefunded the entire symposium fee on Functional Gastrointestinal Accreditation Statement persons who may influence content ofexcept the $50 nonrefundable portion. Disorders” to the hotel staff when This activity has been planned and this CME activity disclose all relevantNo refunds will be made after that time. making your reservation. You can also implemented in accordance with financial relationships with commercial make your reservation online at: http:// the Essential Areas and policies interests in order to allow CME staffEXHIBITS booking.ihotelier.com/istay/istay.jsp?gr of the Accreditation Council for to identify and resolve any potentialThe symposium will feature both oupID=773088&hotelID=73000. Continuing Medical Education conflicts of interest. Faculty must alsononprofit and commercial exhibits. through the joint sponsorship of disclose any planned discussion ofAmple time has been included in the FOUR EASY WAYS TO REGISTER the University of Wisconsin School unlabeled/unapproved uses of drugsprogram to allow you to view the On-line: www.ocpd.wisc.edu/ of Medicine and Public Health and or devices during their presentation(s).exhibits and meet representatives on: course_catalog the International Foundation for Detailed disclosures will be made in By Mail: Return your completed Functional Gastrointestinal Disorders. the activity handout materials.Friday, April 12 registration form & payment. The University of Wisconsin School of7:00 - 8:00 am; 9:50 - 10:50 am; Medicine and Public Health is accredited12:10 - 1:35 pm; 2:55 - 3:30 pm By Phone: 608/262-1397. by the ACCME to provide continuing Please call with your billing medical education for physicians.
10th INTERNATIONAL SYMPOSIUM ON FUNCTIONAL GASTROINTESTINAL DISORDERS APRIL 12–14, 2013 | Milwaukee, Wisconsin University of Wisconsin School of Medicine and Public Health Non-Profit Organization Office of Continuing Professional Development in Medicine and Public Health US Postage School of Medicine 2701 International Lane, Suite 208 PAID and Public Health Madison, WI 53704-3126 Madison, WisconsinUNIVERSITY OF WISCONSIN–MADISON Permit No. 658