Breast Cancer, New Horizons, Current Controversies

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Breast Cancer, New Horizons, Current Controversies

  1. 1. B R E A S T C A N C E RN E W H O R I Z O N SC U R R E N TC O N T R O V E R S I E SJuly 11 – 13, 2013Boston Marriott Long WharfBoston, MassachusettsDirectors:Harold Burstein, MD, PhDJudy Garber, MD, MPHBarbara Smith, MD, PhDEric Winer, MDOffered by:Harvard Medical School Department of Continuing EducationEarn up to 20.5 AMA PR A Category 1 Credits™
  2. 2. Breast Cancer: New Horizons | Current ControversiesJuly 11 – 13, 2013Boston Marriott Long Wharf | Boston, MassachusettsGreetings!We invite you to attend the 2013 Breast Cancer: New Horizons | Current Controversies three-day course jointly sponsored by theHarvard Medical School, Dana-Farber/Brigham and Women’s Cancer Center and Massachusetts General Hospital Cancer Center.This is our 11th year presenting this course, which annually attracts 300–350 oncology clinicians from around the world. Since theinception of this course, we have prioritized the quality of our faculty and worked to optimize the education content, presentation andrelevance to practice. During the last course 93% of our learners told us the course was aligned with the needs of their professionalpractice/activities, 98% said the content was up to date, and 95% said that the format and educational methodologies engaged them inlearning and were appropriate for the desired results.We’ve worked hard to bring you a relevant and useful curriculum and incorporated many suggestions from attendees of the previouscourse. We want to provide you with the best environment in which to learn about evidence based current practices, guidelines,controversies and treatments.This year’s curriculum will address six key learning objectives:• Recognize the molecular heterogeneity of breast cancer and therapeutic implications of HER2+, Triple Negative, and ER+ disease.• Assess the genetic and personal risk factors of breast cancer and the relationship to prevention. • Implement current prevention and survivorship approaches to improve outcomes and quality of life for individuals with breast canceror at increased risk.• Scrutinize challenging clinical cases in the adjuvant and metastatic breast cancer settings through different professional perspectives.• Evaluate clinical trial results for their potential impact on diagnosis, management and treatment of breast cancer.• Apply improvements in breast cancer early detection, local therapy and treatment to patients with breast cancer or individuals withincreased risk.Additionally, there will be several opportunities for specialized learning and personal interactions between faculty and learners.The hotel we’ve partnered with will provide learners the benefit of a “campus-like” experience in the heart of Boston, convenientlylocated steps from desirable dining and sight-seeing destinations. The new completely renovated Boston Marriott Long Wharf offers aspecial rate of $279 per night for our course attendees.We think you will find this course to be a unique and valuable learning experience. Please register early as seats are limited and thecourse fills up quickly. We hope you will join us this July.Best,Harold J. Burstein, MD, PhDDana-Farber/Brigham and Women’s Cancer CenterJudy E. Garber, MD, MPHDana-Farber/Brigham and Women’s Cancer CenterBarbara L. Smith, MD, PhDMassachusetts General Hospital Cancer CenterEric P. Winer, MDDana-Farber/Brigham and Women’s Cancer Center
  3. 3. 2013 Highlights:• Four new and comprehensive lectures• Two Meet the Professor sessions specific to alliedhealth professionals• 2013 ASCO highlights• Three case discussion/tumor boards on challengingmultidisciplinary topics• Seven panel discussions with Q&A• Centrally located within walking distance to Bostons historic sitesCourse DescriptionBreast Cancer: New Horizons|CurrentControversies encompasses the full range ofbreast cancer care from the pathogenesis ofdisease to the barriers that prevent breasthealth care. Innovative developments in cellbiology, genetics, treatment strategies andsurgical techniques offer new opportunitiesfor diagnosing, treating, and defeatingbreast cancer but these advances may leadto comprehension and knowledge gaps forthe target audience (Medical Oncologists,Surgical Oncologists, Radiation Oncologists,Breast Surgeons, General Surgeons,Internists, Physician’s Assistants, NursePractitioners, Oncology Nurses and otherclinicians interested in the care of womenwith breast cancer).The primary goal of Breast Cancer: NewHorizons|Current Controversies is to assisthealth care professionals who care for breastcancer patients to integrate evidence-basedinformation into their practices so thatthey might reduce the disparities in breastcancer screening, diagnosis, treatmentand monitoring. This engaging three-daycourse will offer a rare convergence ofclinical experts in medical, surgical, andradiation oncology who will reinforce amultidisciplinary approach to translatingscientific knowledge into practicalapplications in medicine. Breast Cancer: NewHorzions |Current Controversies will assistclinicians in solving challenging clinicalcases, address controversial topics, and offerpractical treatment strategies. This coursewill provide an intensive, interactive learningenvironment which will educate providerson the most current practices, guidelines,controversies and treatments.Learning ObjectivesUpon completion of this course, participantswill be able to:• Recognize the molecular heterogeneity ofbreast cancer and therapeutic implicationsof HER2+, Triple Negative, and ER+disease.• Assess the genetic and personal risk factorsof breast cancer and the relationship toprevention.• Implement current prevention andsurvivorship approaches to improveoutcomes and quality of life for individualswith breast cancer or at increased risk.• Scrutinize challenging clinical cases inthe adjuvant and metastatic breast cancersettings through different professionalperspectives.• Evaluate clinical trial results fortheir potential impact on diagnosis,management and treatment of breastcancer.• Apply improvements in breast cancer earlydetection, local therapy and treatment topatients with breast cancer or individualsat increased risk.Target audienceMedical oncologists, surgical oncologists,breast surgeons, radiation oncologists,registered nurses, nurse practitioners, andother clinicians interested in the care ofwomen and men with breast cancer.ACCREDITATIONThe Harvard Medical School is accreditedby the Accreditation Council for ContinuingMedical Education to provide continuingmedical education for physicians.The Harvard Medical School designates thislive activity for a maximum of 20.5 AMAPRA Category 1 Credits™. Physicians shouldclaim only the credit commensurate with theextent of their participation in the activity.Nursing contact hours for some sessions havebeen applied for.Dana-Farber Cancer Institute is anapproved provider (#PA-156) of continuingnursing education by the MassachusettsAssociation of Registered Nurses, Inc., anaccredited approver by the American Nurses’Credentialing Center’s Commission onAccreditation.ACGME COMPETENCIESThis course is designed to meet one or moreof the following Accreditation Council ofGraduate Medical Education competencies:• Patient care• Medical knowledge• Practice-based learning and improvement• Interpersonal and communication skills• Professionalism• Systems-based practiceREGISTRATION INFORMATIONEarly Full Tuition (Registrationspostmarked on or before May 31, 2013)Physicians: $525 (USD)Nurse Practitioners, Nurses, andAllied Health Professionals: $425 (USD)Residents/Fellows in Training: $425 (USD)Full Tuition (Registrations postmarkedafter May 31, 2013)Physicians: $600 (USD)Nurse Practitioners, Nurses, andAllied Health Professionals: $500 (USD)Residents/Fellows in Training: $500 (USD)Registration by credit card (VISA orMasterCard) can be made at: www.cme.hms.harvard.edu/courses/breastcancer.Registration by check (draft on a United Statesbank), please make payable to Harvard MedicalSchool and mail with registration form toHarvard Medical School—Departmentof Continuing Education, PO Box 417476,Boston, MA 02241-7476. Telephone or faxregistration is not accepted. Registration withcash payment is not permitted. Upon receipt ofyour paid registration an email confirmationfrom the HMS-DCE office will be sent to you.Be sure to include an email address that youcheck frequently. Your email address is usedfor critical information, including registrationconfirmation, evaluation, and certificate.INQUIRIESBy phone 617-384-8600, Monday–Friday,10 am to 4 pm (EST) or by email at:hms-cme@hms.harvard.edu.ONLINE INFORMATIONTo register or view activity informationonline, visit: www.cme.hms.harvard.edu/courses/breastcancer. To ensure properregistration, please add the first threecharacters of the source code found at thebottom of the registration form.DISCLOSURE POLICYHarvard Medical School (HMS) adheresto all ACCME Essential Areas, Standards,and Policies. It is HMS’s policy that thosewho have influenced the content of a CMEactivity (e.g., planners, faculty, authors,reviewers, and others) disclose all relevantfinancial relationships with commercialentities so that HMS may identify and resolveany conflicts of interest prior to the activity.These disclosures will be provided in theactivity materials along with disclosure ofany commercial support received for theactivity. Additionally, faculty members havebeen instructed to disclose any limitations ofdata and unlabeled or investigational uses ofproducts during their presentations.REFUND POLICYA handling fee of $60 is deducted forcancellation. Refund requests must bereceived by postal mail, email, or fax oneweek prior to this activity. No refunds will bemade thereafter.COURSE LOCATIONAll sessions for this course will beheld at Boston Marriott Long Wharf,296 State Street, Boston, MA 02109(Telephone: 617-227-0800)
  4. 4. 7:15 am Registration and Breakfast 7:50 am Welcoming Remarks Harold J. Burstein, MD, PhD Dana-Farber/Brigham and Women’s Cancer Center SESSION I: Emerging Trends in Breast Cancer Chair: Lawrence Shulman, MD Dana-Farber/Brigham and Women’s Cancer Center8:00–8:20 am The Pathologist in Modern Breast Cancer Care Andrea Richardson, MD, PhD Dana-Farber/Brigham and Women’s Cancer Center8:20–8:40 am Genomic Profiling in Breast Cancer Nikhil Wagle, MD Dana-Farber/Brigham and Women’s Cancer Center8:40–9:00 am Updates on Post-Mastectomy Radiation Jay Harris, MD Dana-Farber/Brigham and Women’s Cancer Center9:00–9:15 am Questions and Discussion9:15–9:25 am Break9:25–9:45 am Opportunities for Immunological Therapies in Breast Cancer M. Nora Disis, MD Fred Hutchinson/University of Washington Cancer Consortium9:45–10:05 am Emerging Trends in Reconstructive and Plastic Surgery Amy Colwell, MD Massachusetts General Hospital Cancer Center10:05–10:20 am Questions and Discussion LECTURE & CASE DISCUSSION/TUMOR BOARD10:20–10:50 am Inflammatory Breast Cancer Beth Overmoyer, MD, FACP Dana-Farber/Brigham and Women’s Cancer Center10:50–11:00 am Break11:00–12:00 pm Case Discussion/Tumor Board – Locally Advanced Breast Cancer Chair: Craig Bunnell, MD, MPH, MBA Dana-Farber/Brigham and Women’s Cancer Center Panel: TBD12:00–1:00 pm Lunch (on your own) SESSION II: Prevention Chair: Ann Partridge, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center1:00–1:20 pm Future Directions in Prevention TBD1:20–1:40 pm Surgical Approaches to Risk Reduction: Who, When, Why, and How? Suzanne Coopey, MD Massachusetts General Hospital Cancer Center1:40–2:00 pm Hormones, Phyto-Estrogens, and Endocrine Disrupters Wendy Chen, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center2:00–2:15 pm Questions and Discussion2:15–2:25 pm Break LECTURE2:25–2:55 pm Meeting the Needs of Breast Cancer Patients Around the World Lawrence Shulman, MD Dana-Farber/Brigham and Women’s Cancer Center SESSION III: Survivorship Chair: Ann Partridge, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center2:55 -3:15 pm Complications and Late Effects of Local Therapy Laura Dominici, MD Dana-Farber/Brigham and Women’s Cancer Center3:15–3:35 pm Sexual Health TBD3:35–3:55 pm Exercise and Breast Cancer Jennifer Ligibel, MD Dana-Farber/Brigham and Women’s Cancer Center3:55–4:05 pm Break4:05–4:25 pm Obesity and Inflammation Before, During, and After Breast Cancer Cliff Hudis, MD Memorial Sloan-Kettering Cancer Center4:25–4:45 pm New Modes for Survivorship Care Ann Partridge, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center4:45–5:00 pm Questions and Discussion SPECIAL SESSIONS5:00–6:00 pm Meet the Professor Sessions TBD6:00 pm Adjourn for the DayCOURSE SCHEDULE | THURSDAY, JULY 11, 2013
  5. 5. 7:15 am Breakfast LECTURE8:00–8:35 am Pain Management in Breast Cancer Janet Abrahm, MD Dana-Farber/Brigham and Women’s Cancer Center SESSION IV: Special Populations and Risk Factors in Breast Cancer Chair: Craig Bunnell, MD, MPH, MBA Dana-Farber/Brigham and Women’s Cancer Center8:35–8:55 am Using Genetic Information in Patient Care Judy Garber, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center8:55–9:15 am Premalignant Lesions Faina Nakhlis, MD Dana-Farber/Brigham and Women’s Cancer Center9:15–9:35 am Grappling with Comorbidity in the Elderly Rachel Freedman, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center9:35–9:50 am Questions and Discussion9:50–10:00 am Break10:00–10:20 am Local and Systemic Breast Cancer Care in the Elderly Hy Muss, MD University of North Carolina, Chapel Hill10:20–10:40 am Cultural Disparities in Communication Beverly Moy, MD, MPH Massachusetts General Hospital Cancer Center10:40–11:00 am Costs and Economics of Breast Cancer Barbara Smith, MD, PhD Massachusetts General Hospital Cancer Center11:00–11:15 am Questions and Discussion11:15–11:25 am Break SCHLAGER LECTURE11:25–11:50 am George Sledge, MD, Stanford Cancer Center11:50–1:00 pm Lunch / Meet the Professor (sign up in advance, TBD) SESSION V: HER2+ Breast Cancer Chair: Eric Winer, MD Dana-Farber/Brigham and Women’s Cancer Center1:00–1:20 pm HER2+ Testing and Beyond: Predicting the Benefits of TBD Anti-HER2+ Treatment 1:20–1:40 pm Targets to Watch in Breast Cancer Ian Krop, MD, PhD Dana-Farber/Brigham and Women’s Cancer Center1:40–2:00 pm Adjuvant Therapy of HER2+ Breast Cancer Eric Winer, MD Dana-Farber/Brigham and Women’s Cancer Center2:00–2:20 pm Patterns of Care in Advanced Breast Cancer Nancy Lin, MD Dana-Farber/Brigham and Women’s Cancer Center2:20–2:35 pm Questions and Discussion2:35–2:45 pm Break SESSION VI: Triple Negative Disease Chair: Judy Garber, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center2:45–3:05 pm Biology, Heterogeneity and Natural History of Triple Lisa Carey, MD Negative Breast Cancer University of North Carolina, Chapel Hill3:05–3:25 pm DNA Repair Deficiencies in Triple Negative Metastatic Disease Dan Silver, MD, PhD Dana-Farber/Brigham and Women’s Cancer Center3:25 -3:45 pm Treatment Options for Patients with Triple Negative Metastatic Disease Steven Isakoff, MD, PhD Massachusetts General Hospital Cancer Center3:45–4:00 pm Questions and Discussion4:00–4:10 pm Break4:10–4:30 pm Management of Refractory Breast Cancer: Update on Novel Chemotherapy Erica Mayer, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center4:30–4:50 pm Treatment of Oligometastatic Disease Sara Tolaney, MD, MPH Dana-Farber/Brigham and Women’s Cancer Center4:50–5:05 pm Questions and Discussion5:05–5:15 pm Break CASE DISCUSSION/TUMOR BOARD5:15–6:15 pm Metastatic Case Discussion Chair: Harold Burstein, MD, PhD Dana-Farber/Brigham and Women’s Cancer Center6:15 pm Adjourn for the Day6:30 pm Networking Reception COURSE SCHEDULE | Friday, July 12, 2013
  6. 6. COURSE SCHEDULE | saturday, July 13, 20137:15 am Breakfast CASE DISCUSSION/TUMOR BOARD8:00–9:00 am Challenging Cases in the Adjuvant Setting Chair: Harold Burstein, MD, PhD Dana-Farber/Brigham and Women’s Cancer Center SESSION VII: ADVANCES IN LOCAL THERAPY Chair: TBD Radiation Oncology9:00–9:20 am Lessons from Neoadjuvant Therapy W. Fraser Symmans, MD The University of Texas MD Anderson Cancer Center9:20–9:40 am Partial Breast Radiation: What’s New? Alphonse Taghian, MD Massachusetts General Hospital Cancer Center9:40–10:00 am DCIS: Who Doesn’t Need Radiation? Julia Wong, MD Dana-Farber/Brigham and Women’s Cancer Center10:00–10:20 am Radiation Oncology: What’s New? Jennifer Bellon, MD Dana-Farber/Brigham and Women’s Cancer Center10:20–10:35 am Questions and Discussion10:35–10:45 am Break Surgical Oncology10:45–11:05 am Margins: How Much Is Enough? Jane Brock, MBBS, PhD Dana-Farber/Brigham and Women’s Cancer Center11:05–11:25 am Surgical Management after Preoperative Therapy Kelly Hunt, MD, FACS The University of Texas MD Anderson Cancer Center11:25–11:45 am Management of the Axilla Mehra Golshan, MD, FACS Dana-Farber/Brigham and Women’s Cancer Center11:45–12:00 pm Questions and Discussion12:00–12:10 pm Break12:10–1:10 pm HIGHLIGHTS FROM ASCO 2013 Harold Burstein, MD, PhD Dana-Farber/Brigham and Women’s Cancer Center1:10 pm Concluding Remarks and Adjourn1:15 pm Box Lunch (sign up in advance)
  7. 7. REGISTRATION INFORMATIONBREAST CANCER | CURRENT CONTROVERSIES | NEW HORIZONS | July 11 – 13, 2013You are encouraged to register early as space is limited.For additional course information, including complete faculty biographies, pleasevisit www.cme.hms.harvard.edu/courses/breastcancer.Early Full Tuition (Registrations postmarked on or before May 31, 2013)• Physicians: $525 (USD)• Nurse Practitioners, Nurses, and Allied Health Professionals: $425 (USD)• Residents/Fellows in Training: $425 (USD)Full Tuition (Registrations postmarked after May 31, 2013)• Physicians: $600 (USD)• Nurse Practitioners, Nurses, and Allied Health Professionals: $500 (USD)• Residents/Fellows in Training: $500 (USD)Print Name Clearly – All Fields RequiredFull Name First Middle Initial LastMailing Address Street City State Zip CodeDaytime Phone ( ) Fax Number ( )PLEASE NOTE: Your email address is used for critical information about the course including: registration confirmation,course evaluation, and certificate. Please be sure to include an email address you check daily or frequently.Email Address• Please check if you wish to be excluded from receiving email notices of future hms-dce programs.Profession DegreePrimary Specialty (Physicians Only) Board Certified: • Yes • NoProfessional School Attended (Physicians Only):• Harvard Medical School • U.S. Medical School• International Year of Graduation• Please circle the optional sessions you will attend. See details on the course agenda.A. Optional Meet the Professor session: July 11, 2013 at 5:00 pmB. Optional Meet the Professor lunch: July 12, 2013 at 11:50 amC. Box Lunch registration: July 13, 2013   Please check if vegetarianIf you require special assistance (wheelchair, auxiliary aids) or special dietary requirements,please indicate and we will contact you. • YesThe beautifully renovated BostonMarriott Long Wharf offers an idealdowntown location, spectacularwaterfront views and top-notch service.Rooms are limited, so please book early.ACCOMMODATIONS/TRAVELA limited number of rooms have beenreserved at Boston Marriott Long Wharf(Telephone: 617-227-0800) until June 20,2013. Please identify yourself as a “BreastCancer Course” attendee and provide theGroup Code to receive the reduced roomrate of $279 per night Single/Double.Hotel arrangements can also be madeonline at: http://www.marriott.com/hotels/travel/boslw-boston-marriott-long-wharf/. Enter Group Code: bccbccafor online reservations. Please do notpurchase non-refundable airline ticket(s)until you have received an email from ouroffice confirming your paid registration.For airline reservations contact the HMSTravel Desk toll free 1-877-4-HARVMD(1-877-442-7863) Monday–Friday 9 am–8 pm(EST). From outside the U.S., Canada, andVirgin Islands, please call 617-559-3764.Breast CancerNew HorizonsCurrent ControversiesJuly 11 – 13, 2013Boston Marriott Long Wharf296 State StreetBoston, MA 02109617-227-0800Course number is 331279✃ Online Registrants – add the first three charactersof the Source Code found here ➞ Source Code: A W E B B C D E F G X Z Z Z

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