Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013

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Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013

  1. 1. North Carolina’s Life Sciences Cluster Impact of the North Carolina Biotechnology Center 21 August 2013 Mark Lombard, MBA Program Director, Bioscience Industrial Development North Carolina Biotechnology Center
  2. 2. North Carolina, USA NORTH CAROLINA BIOTECHNOLOGY CENTER
  3. 3. Life Sciences in North Carolina • Place – 3 major research universities in a 30 mile radius – Ecosystem of supportive organizations, risk capital, entrepreneurial culture • People – Collaboration among visionary business, academia, gov’t leaders – Attract and retain scientific and business talent • Programs – Company creation, attraction, retention, expansion programs – Innovative workforce development programs • Patience – North Carolina Biotechnology Center: 30 years – Research Triangle Park: 50+ years NORTH CAROLINA BIOTECHNOLOGY CENTER
  4. 4. Brazil and North Carolina NORTH CAROLINA BIOTECHNOLOGY CENTER
  5. 5. NORTH CAROLINA BIOTECHNOLOGY CENTER
  6. 6. Brazil and North Carolina NORTH CAROLINA BIOTECHNOLOGY CENTER
  7. 7. Sao Paulo and North Carolina Sao Paulo (2012) North Carolina (2012) • Population: 41,901,219 • Density: 170/km2 • GDP (2010) • Population: 9,752,073 • Density: 83/km2 • GDP (2010) – US$615M – US$15,322 per capita • Machinery, auto and aviation, services, finance, textiles, oranges, sugar cane, coffee, life sciences – $407M – $42,884 per capita • Cotton, tobacco, hogs, chickens, textiles, furniture • Finance, advanced mfg, IT, life sciences NORTH CAROLINA BIOTECHNOLOGY CENTER
  8. 8. BIOTECHNOLOGY IN NORTH CAROLINA NORTH CAROLINA BIOTECHNOLOGY CENTER
  9. 9. Biotechnology: Heal, Fuel, Feed the World Global Challenges • Human/Animal health • Food availability & security • Energy • Environmental sustainability NORTH CAROLINA BIOTECHNOLOGY CENTER
  10. 10. Biotech in NC – Large and Diverse • 3rd Largest Life Science Cluster in the US – Medical Devices & Diagnostics – Contract Research & Manufacturing – Biopharma – Agricultural Biotech 560+ Companies 60,000+ Employees 21% 21% 58% R&D CRO/Testing Mfg/Prod
  11. 11. Specialization Biotech in NC – Fastest Growing Growth Rate NORTH CAROLINA BIOTECHNOLOGY CENTER
  12. 12. Biotech in NC – High Impact Jobs • Average salary - $78,348 – Nearly double the state’s private sector average • 3.6 additional jobs for each biotech job • 226,000 total jobs NORTH CAROLINA BIOTECHNOLOGY CENTER
  13. 13. Biotech in NC – Annual Economic Impact • Direct biotechnology sector revenues $41.2 billion • Employee compensation $12.7 billion • State and local revenues $1.92 billion NORTH CAROLINA BIOTECHNOLOGY CENTER
  14. 14. THE NORTH CAROLINA BIOTECHNOLOGY CENTER NORTH CAROLINA BIOTECHNOLOGY CENTER
  15. 15. NCBiotech – Mission To provide long-term economic and societal benefits to North Carolina through support of biotech research, business, education and strategic policy statewide. NORTH CAROLINA BIOTECHNOLOGY CENTER
  16. 16. NCBiotech – What We Do • State-funded, private, non-profit corporation • Portfolio of programs – Research – Business – Education – Economic Development NORTH CAROLINA BIOTECHNOLOGY CENTER
  17. 17. NCBiotech – Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
  18. 18. NCBiotech – Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
  19. 19. Research Support • Grant funding for: – New research ideas – Build capacity – equipment/faculty – University/Company research projects • $98 million granted • $4 to $70 leveraged NORTH CAROLINA BIOTECHNOLOGY CENTER
  20. 20. NCBiotech – Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
  21. 21. Company Creation and Growth: NCBiotech Loan Program • $50K - $250K low interest loans • ROI = $117 per $1 loaned
  22. 22. Notable Recent Successes $96 million acquisition $25 million IPO BioKier $1.7 million seed financing Up to $1.6 million grant NORTH CAROLINA BIOTECHNOLOGY CENTER
  23. 23. Advanced Liquid Logic Microfluidics Lab Instruments • • • • • • • 2003: $50,000 CFG Aug-2004: Company founded May-2005: $15,000 BDL – 1 employee Sep-2005: $72,600 SBR – 3 employees Sep-2006: $160,000 SGL – 6 employees Jun-2009: $220,500 SGL – 24 employees 2011: Launched products for newborn screening, genomic sample prep • 2011-2013: NCBiotech VC events in Palo Alto, Boston, NYC • Aug-2012 : $100,000 IFP • Jul-2013 : $96M acquisition by Illumina – 80 employees – All loans repaid in full + interest and warrants – >$50 million follow-on funding before acquisition • Introductions to bankers and investors, NCBIP, Library, Jobs Board, NCBiotech Partnering 2011-2013, Corporate Communications
  24. 24. Heat Biologics Cell-based Cancer Immunotherapy • • • • 2008: Company founded in FL Aug-2011: Recruited to NC 2011-2012: Assistance with investor pitch 2011-2012: NCBiotech VC events in Palo Alto, Boston • Nov-2011: $225,000 SGL - 2 NC employees – Repaid in full with interest + warrants • • • • Apr-2012: Industrial Internship Program Apr-2013: $5 million VC round Jul-2013: $25 million IPO – NASDAQ:HTBX – 5 NC employees Investor introductions, partner introductions, foundation introductions, BATON, Library, Corporate Communications, NCBiotech Partnering 2012, BIO Pavilion
  25. 25. BioKier “Medicinalize” Gastric Bypass for Diabetes • • • • • • Nov-2008: Company founded Oct-2010: Emerging Company Preview Oct-2010: $250,000 SRL – 2 employees Oct-2012: Pitch Scrub Nov-2012: SEBIO Presentation Apr-2013: Southeast Venture Philanthropy Summit • May-2013: $250,000 SGL – 3.5 employees • Jul-2013: $1.7 million Broadview Ventures, AHA • Investor introductions, NCBIP, Corporate Communications, Library, NCBiotech Partnering 2011-2013, LSBDP, Biotech Forums
  26. 26. Eboo Pharmaceuticals Opioid Modulators for CNS Diseases • • • • • • • • • • • Feb-2012: Company founded May-2012: $30,000 CIL – 2 NC employees Jun-2012: Introduction to Biogen IDEC Jul-2012: SBIR letter of support, recommended MJFF Oct-2012: Introductions to CEO candidates Nov-2012: Advice on business plan, investor pitch Dec-2012: Emerging Company Preview Feb-2013: Facilitated meeting with Eli Lilly Apr-2013: Southeast Venture Philanthropy Summit Jun-2013: Up to $1.6M grant Michael J. Fox Foundation BATON, Corporate Communications, Library
  27. 27. NCBiotech – Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
  28. 28. Statewide Offices – Western (Asheville) – Greater Charlotte – Piedmont Triad (Winston-Salem) – Research Triangle Park – Eastern (Greenville) – Southeastern (Wilmington) NORTH CAROLINA BIOTECHNOLOGY CENTER
  29. 29. Economic Development Since July 2010 • 21 projects • 1,754 employees Ripple effects: • 7,803 total jobs • $490 million in payroll • $59 million in state and local revenues • $2.0B in economic activity NORTH CAROLINA BIOTECHNOLOGY CENTER
  30. 30. Economic Development Novartis Vaccines • BIO 2004 in San Francisco – Chiron • • • • • • 2006: project announced 2009: plant opens 2012: production begins 2012: $36M expansion 2013: $60M expansion Today: >$1B invested, 700 employees, will grow to 1000 NORTH CAROLINA BIOTECHNOLOGY CENTER
  31. 31. Economic Development Medicago • Early 2010: introduced by Canadian Consulate • Mid 2010: DARPA, ARE • Late 2010: construction begins • Mid 2012: 10M flu doses in one month • 2013: Acquired by Mitsubsihi in a $357M deal NORTH CAROLINA BIOTECHNOLOGY CENTER
  32. 32. Economic Development Recent Announcements • 2011: Sequenom (molecular diagnostics) – 242 jobs, $19M investment • 2012: Aerocrine (asthma diagnostics) – 45 jobs • 2013: bioMerieux: (in vitro diagnostics) – 44 jobs, $44M investment • 2013: Syngenta (agricultural biotech) – 150 jobs, $94M investment NORTH CAROLINA BIOTECHNOLOGY CENTER
  33. 33. NCBiotech – Programs Research Support Ideas Company Creation and Growth Statewide Econ Devel Products, Companies and Jobs Education, Networking and Other Programs NORTH CAROLINA BIOTECHNOLOGY CENTER
  34. 34. Workforce and Education • 1900+ teachers trained • 50,000 students reached each year • $7M in grants for lab equipment & new courses • 8,000+ BioWork manuals distributed to colleges NORTH CAROLINA BIOTECHNOLOGY CENTER
  35. 35. Biomanufacturing Workforce NCBIOIMPACT • Industry-driven biopharma manufacturing training and education • Emerging and existing labor • BTEC – 82,500 SF; $60M – $12.5M equipment – cGMP pilot plant NORTH CAROLINA BIOTECHNOLOGY CENTER
  36. 36. Networking and Community • High-profile conferences • Hamner Conference Center – 30,000 guests annually • Networking groups – More than 3,000 attendees • Biotech Library • NCBiotech Job Network • And much more NORTH CAROLINA BIOTECHNOLOGY CENTER
  37. 37. Looking Ahead NORTH CAROLINA BIOTECHNOLOGY CENTER
  38. 38. Supportive Ecosystem
  39. 39. Life Sciences in North Carolina • Place – 3 major research universities in a 30 mile radius – Ecosystem of supportive organizations, risk capital, entrepreneurial culture • People – Collaboration among visionary business, academia, gov’t leaders – Attract and retain scientific and business talent • Programs – Company creation, attraction, retention, expansion – Innovative workforce development programs • Patience – North Carolina Biotechnology Center: 30 years – Research Triangle Park: 50+ years NORTH CAROLINA BIOTECHNOLOGY CENTER
  40. 40. Thank You Mark Lombard Program Director, Bioscience Industrial Development North Carolina Biotechnology Center

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