FOR GRADUATE STUDENTS
AND PARTICIPATING FACULTY
University Offices 7
University Graduate School Offices
Biological and Biomedical Sciences
Medical Scientist Training Program
Special University Offices
The Graduate Program in Neuroscience 10
Requirements for the Ph.D. Degree 12
Requirements for MD/PhD Students 16
Procedures for the Qualifying Examination,
Thesis Prospectus and the Dissertation
Foreign Student Registration
In Absentia Registration
Leave of Absence
Financial Aid 24
Lectures, Seminars and Journal Clubs 26
Off-Campus Neuroscience Courses 28
Campus Facilities 30
Recreational Opportunities 36
Faculty Research Interests 37
Neuroscience Courses 44
Interdepartmental Neuroscience Program & BBS Students
Name Advisor/Dept Campus Address Campus Phone Campus Fax
Addy, Nii Picciotto/Psychiatry 301 Cedar 737-2042 737-2043
Bellemer, Andy Koelle/MB&B CE 30 SHM 737-2271 785-6404
Bender, Genevieve Small/JPL JPL 401-6210 624-4950
Berman, Rachel Blumenfeld/Neurology LCI 1007 785-6470 737-2538
Brown, Rebecca# Strittmatter/Neurology 301 Cedar St. 785-4173 785-5971
Carey, Allison* Carlson/MCDB KBT 1132 432-3542 432-6161
Casale, Amanda# Miesenbock/Cell Biology 785-5971
Colli, Christian# Zhong/MCDB 785-5971
Davis, Denise Strittmatter/Neurology 301 Cedar 785-5030 785-5098
Davis, Doug* Pieribone/Pierce JPL 401-6252 624-4950
Egan, Kathy Bordey/Neurosurgery FMB 429 737-2500 737-2159
Einstein, Emily# Yeckel/Neurobiology B 432 SHM 737-1032 785-5971
Englot, Dario* Blumenfeld/Neurology LCI1007 785-6470 737-2538
Frost, Adam* Unger/MB&B CE 16 SHM 785-5784 785-6404
Gamo, Nao# Arnsten/Neurobiology B428 SHM 785-3066 785-5971
Ghaznavi, Sharmin* Johnson/Psychology SSS 432-7132 432-4617
Gipson, Keith* Yeckel/Neurobiology B 432 SHM 737-1032 785-5263
Golomb, Julie Chun/Psychology 317 SSS 432-9621 432-7171
Gourley, Shannon Taylor/Psychiatry CMHC 3rd
fl. 974-7729 974-7897
Gray, Sarah# Horvath/Comparative Medicine LSOG 785-5971
Guez, Danielle* Picciotto/Psychiatry 301 Cedar 737-2042 737-2043
Heath, Chris Picciotto/Psychiatry 301 Cedar 737-2042 737-2043
Horst, Nicole Laubach/Pierce JPL 401-6257 624-4950
Huebner, Eric* Strittmatter/Neurology 301 Cedar 785-5030 785-5098
Hunsberger, Josh Duman/Psychiatry CMHC 3rd
fl 974-7734 974-7897
Johnson, Matt R.# Constable/Diagnostic Rad. TAC N135 737-2835 785-6534
Jones, Warren Klin/Child Study Center SHM G-132 785-3499 737-4197
Jung, Yon Woo# Koelle/MB&B CE 30 SHM 737-2271 785-5971
Kimchi, Eyal* Laubach/Pierce Lab JPL 401-6257 624-4950
Kinsler, Rebecca# Beech/Psychiatry 300 George St. 785-5971
Krause, Matt Mazer/Neurobiology I412 SHM 785-5263
Krueger, Dilja Nairn/Psychiatry CMHC 3rd
fl. 974-7753 974-7897
Kwan, Ken Sestan/Neurobiology C320 SHM 737-1435 785-5263
Lacar, Ben Bordey/Neurosurgery FMB 429 737-2500 737-2159
Letinic, Kresimir Rakic/Neurobiology C319 SHM 785-5418 785-5263
Martushova, Katherine Strittmatter/Neurology 301 Cedar 785-5030 785-5098
Masurkar, Arjun* Chen/Neurobiology 236 FMB 785-5263
Maynard, Kristen# Lavik/Biomedical Engineering MEC 311 785-5971
Narayanan, Kumar* Laubach/Pierce JPL 401-6211 624-4950
Newhouse, Kristi Small/Pierce JPL 401-6210 624-4950
Park, James* Strittmatter/Neurology 301 Cedar 785-4971 785-5098
Rabenstein, Reba Picciotto/Psychiatry 301 Cedar 737-2042 737-2043
Robbins, Elissa Biederer/MB&B C129 SHM 737-1002 785-6404
Sears, Rob DiLeone/Psychiatry Basemt CMHC 974-7677 974-7897
Snyder, Derek Bartoshuk/Surgery (ENT)
Strumbos, John Kaczmarek/Pharmacology B 316c SHM 785-7670
Thomas, Lisa Biederer/MB&B C 129 SHM 737-1002 785-6404
Trinko, Rich% DiLeone/Psychiatry Basemt CMHC 974-7677 974-7897
Ua Cruadhlaoich, Matt Richerson/Neurology LCI 712C 737-2893 785-5694
von Hehn, Christian Jordt/Pharmacology SHM B326a 785-5971
Williams, Cicely Lavik/Biomed Eng MEC 311 432-0030
Wiseman, Shari# Wells/MCDB KBT 226 785-5971
Yao, Andrea Carlson/MCDB 1132 KBT 432-3542
Yang, Yvonne* Strittmatter/Neurology 301 Cedar St. 785-4173 785-5098
Young, Stephanie Bordey/Neurosurgery FMB 429 737-2500 737-2159
# First year Neuroscience Track student
% VAIR student
Bi, Linda* Matthews Ithaca, NY
Brennan, Avis Arnsten B428 SHM 785-3066 785-5263
Breunig, Josh Rakic C324 SHM 737-1362 785-5263
Hagenston, Anna Yeckel B 436 SHM 737-1032 785-5263
Haider, Bilal McCormick C303 SHM 785-5263
Johnson, Matt Sestan B302 SHM 737-1435 785-5263
Kraus, Mike Bruce B435 SHM 785-5164 785-5263
McRae, Paulette Matthews Ithaca, NY
Vijayraghavan, Susheel Arnsten B404 SHM 785-5711 785-5263
Whitman, Mary* Greer FMB 430 785-4230 737-2159
Zoncu, Roberto Rakic C303 SHM 785-5418 785-5263
First Name Last Name Title Department Address Phone Fax
Meenakshi Alreja Assoc. Prof. Psychiatry 335A CMHC 974-7762 974-7897
Amy Arnsten Professor Neurobiology B428 SHM 785-4431 785-5263
Thomas Biederer Asst Prof. MB&B C 127 SHM 785-5465 785-6404
Hal Blumenfeld Asst. Prof. Neurology LCI 1007 785-3928 737-2538
Angélique Bordey Assoc Prof Neurosurgery FMB 422 737-2515 737-2159
Walter Boron Professor Physiology B128 SHM 785-4070 785-4951
Charlie Bruce Assoc. Prof. Neurobiology B439 SHM 737-2727 785-5263
Benjamin Bunney Professor Psychiatry 300 George Ste 901 785-6396 785-6196
John Carlson Professor MCDB KBT 1132 432-3541 432-6161
Wei Chen Asst. Prof. Neurobiology FMB 231 785-5459 785-5263
Marvin Chun Professor Psychology KH/318 SSS 432-9620 432-7172
Larry Cohen Professor Physiology BE58 SHM 785-4047 785-4951
Todd Constable Professor Diag. Radiology TAC N135 737-2768 785-6534
Pietro De Camilli Professor Cell Biology 236 BCMM 737-4465 737-1762
Nihal DeLanerolle Professor Neurosurgery FMB 414 785-3258 737-2159
Sabrina Diano Asst Prof OB/Gyn LSOG 401 737-1216 785-4747
Ron Duman Professor Psychiatry S308 CMHC 974-7726 974-7724
Barbara Ehrlich Professor Pharmacology B207 SHM 737-1158 785-7670
Paul Forscher Professor MCDB KBT 222 432-6344 432-8999
Karyn Frick Asst. Prof. Psychology DL 210 432-4673 432-7172
Jeremy Gray Asst. Prof. Psychology SSS 212 432-9615 432-7172
Charles Greer Professor Neurosurgery FMB 412 785-4034 737-2159
Lise Heginbotham Assoc Prof. MB&B Bass 234 432-9803 432-5175
Tamas Horvath Chair Comparative Medicine LSOG 117 785-2525 785-4747
Jim Howe Assoc Prof Pharmacology B251a SHM 737-2398 785-7670
Marcia Johnson Professor Psychology KH; SSS 306c 432-6761 432-4617
Sven-Eric Jordt Asst. Prof. Pharmacology SHM B 163c 785-2159 785-7670
Len Kaczmarek Professor Pharmacology B316c SHM 785-4500 785-7670
Doug Kankel Professor MCDB KBT 1118 432-3532 432-6161
Haig Keshishian Professor MCDB KBT 640 432-3478 432-6161
Ken Kidd Professor Genetics I351 SHM 785-2654 785-6568
Jeff Kocsis Professor Neurology Bld 34 VAMC 937-3802 937-3801
Michael Koelle Assoc Prof MB&B SHM CE 28a 737-5808 785-6404
Tony Koleske Assoc Prof MB&B CE 31 SHM 785-5624 785-7979
Hür Koser Asst Prof Elect. Engineering BCT 507 432-9629 432-7769
Robert LaMotte Professor Anesthesiology BML 419 737-2720 737-5220
Mark Laubach Asst. Prof. Pierce Lab JPL 401-6202 624-4950
David LaVan Asst. Prof. Mech. Eng. Mason Labs M3 432-9662 432-7654
Erin Lavik Asst. Prof. Biomed Eng. MEC 311 432-4265 432-0030
Tom Lentz Professor Cell Biology C324 SHM 785-4565 785-7226
Michael Levene Asst. Prof. Biomed. Eng. MEC 313 432-4262 432-0030
Daeyeol Lee Assoc Prof Neurobiology C303 SHM 785-3527 785-5263
Jamie Mazer Asst. Prof. Neurobiology I412 SHM 737-5853 785-5263
Greg McCarthy Professor Psychology KH
David McCormick Professor Neurobiology I409 SHM 785-4577 737-5223
First Name Last Name Title Department Address Phone Fax
Gero Miesenböck Assoc Prof Cell Biology 254C BCMM 785-3725
Mark Mooseker Professor MCDB KBT 352 432-3468 432-5059
Angus Nairn Professor Psychiatry CMHC S307 974-7725 974-7724
Dhasakumar Navaratnam Asst. Prof. Neurology LLCI 703 785-5755 785-5694
Michael Nitabach Asst Prof C&M Physiology BE 29 SHM 737-2939 785-4951
Marina Picciotto Assoc Prof Psychiatry 301 Cedar 737-2041 737-2043
Vincent Pieribone Assoc Prof Pierce Lab JPL 401-6214 624-4950
Maria M. Piñango Assoc Prof Linguistics 370 Temple 305 432-8289 432-4087
Pasko Rakic Professor Neurobiology C323a SHM 785-4330 785-5263
George Richerson Assoc Prof Neurology 712 LCI 737-1461
Robert Roth Professor Pharmacology 300 George 8300 785-4506 785-5275
Gary Rudnick Professor Pharmacology B326 SHM 785-4548 785-7670
Mark Saltzman Professor Biomedical Engineering MEC 413 432-4262
Laurie Santos Asst. Prof. Psychology KH; SSS 314e 432-4524 432-7172
Joseph Santos-Sacchi Professor Surgery (Otol.) BML 244 785-7566 737-2245
Glenn Schafe Asst. Prof. Psychology KH, DL 204 432-3461 432-7172
Ilsa Schwartz Professor Surgery (Otol.) 232 BML 785-6329 737-2245
Mike Schwartz Assoc Prof Neurobiology C327B SHM 785-4324 785-6331
Nenad Sestan Asst Prof Neurobiology C323C SHM 737-2190 737-1435
Gordon Shepherd Professor Neurobiology FMB 236 785-4336 785-6990
Fred Sigworth Professor Physiology BE 42 SHM 785-5773 785-4951
Dana Small Asst. Prof. Pierce Lab JPL 401-6204 624-4950
Matthew State Assoc Prof Child Study I383 SHM/
Elke Stein Asst Prof MCDB KBT 232 432-8402 432-6161
Stephen Strittmatter Professor Neurology 184 Liberty CP 318 785-4878 785-5098
Jane Taylor Assoc Prof Psychiatry CMHC Room S307 974-7727 974-7724
Ning Tian Asst. Prof. Ophthalmology BML 212 785-2723 785-7401
Susumu Tomita Asst. Prof. C&M Physiology SHM BE11 785-7201 785-4951
Vinzenz Unger Asst. Prof. MB&B SHM CE 25 785-5652 785-6404
Flora Vaccarino Assoc Prof Child Study Ctr I266 SHM 737-4147 785-7611
Allan Wagner Professor Psychology KH 432-4691 432-7563
Xiao-Jing Wang Professor Neurobiology C303 SHM 785-6297 785-5263
Stephen Waxman Professor Neurology 708 LCI 785-5947 785-7826
David Wells Asst. Prof. MCDB KBT 226 432-3481 432-6161
Robert Wyman Professor MCDB KBT 610 432-3475 432-6161
Tian Xu Assoc Prof Genetics BCMM 236c 737-2623 737-1762
Mark Yeckel Asst. Prof. Neurobiology B436 SHM 785-5581 785-5263
David Zenisek Asst. Prof. Physiology B 114 SHM 785-6474 785-4951
Weimin Zhong Assoc Prof MCDB KBT 616B 432-9233 432-6161
Yufeng Zhou Asst. Prof. C&M Physiology SHM BE 07 785-7388 785-4951
Steven Zucker Professor Comp Science AKW 507 432-6434 432-0593
Patrick Allen Asst. Prof. Psychiatry 335D CMHC 974-7763 974-7897
Bob Beech Asst. Prof. Psychiatry 300 George St.
Joel Black Res Sci. Neurology Bldg 34 VAMC 937-3802 937-3801
Hilary Blumberg Assoc. Prof. Psychiatry 470 Congress
Ted Carnevale Sr Res Sci. Psychology KH 432-8931 432-3440
Ralph DiLeone Asst Prof Psychiatry CMHC 3rd fl
Albert Lo Asst. Prof. Neurology LCI 7 932.5711.5
Laura Manuelidis Professor Surg (Neuropath) FMB 11 785-4442 785-6381
Rory McCrimmon Asst Prof Internal Medicine (Endoc.) LMP 1093/ TAC S130 785-4664
Sam Sathyanesan Asst Prof Psychiatry CMHC 3rd fl
Robert Sherwin Professor Internal Medicine (Endoc.) LMP 1093 785-4183
James Swain Asst Prof Child Study Center NIHB 205 785-6973 785-7611
Michael Westerveld Asso. Prof. Neurosurgery TMP 4 562-4090
Anne Williamson Asso. Prof. Neurosurgery FMB 410 785-5327 737-2159
NEUROSCIENCE TRACK ADMINISTRATIVE OFFICES
Campus Address Phone Fax Number
INP Co-Director Haig Keshishian 640 KBT 432-3478 432-6161
INP Co-Director Charles Greer FMB 412 785-4034 737-2159
Neurobiology DGS Amy Arnsten B428 SHM 785-4431 785-5263
Charles Greer FMB 412 785-4034 737-2159
Carol Russo L200 SHM 785-5932 785-5971
Lynne Baumgarten C303 SHM 785-4323 785-5263
Yale Graduate School
Dean Jon Butler 112 HGS 432-2733 FAX 432-2442
Assistant to Dean Diane Hovey 112 HGS 432-2789
Associate Dean Richard Sleight 134 HGS 432-2744 FAX 432-6904
Assistant Dean 134 HGS 432-1884
Assistant to Dean Theresa Dio 134 HGS 432-2744
Admissions Office 117 HGS 432-2771
(questions related to admission or readmission to the Graduate School)
Registrar 246 Church St. 432-2336
(registration; course schedules; grades; petitions for Master's Degrees; transcripts)
Graduate Registrar 113 HGS 432-2743
(applications for departmental transfer; leaves of absence, withdrawal)
Financial Aid Office Jennifer Brinley 129 HGS 432-7980
(loan applications; administration and payment of fellowships)
Information Office 140 HGS 432-2770
(general information; dissertation submission packets)
McDougal Center Lisa Brandes 122 HGS 432-2583
(McDougal Fellows, Orientation, Commencement, etc.)
BIOLOGICAL AND BIOMEDICAL SCIENCES
Director Lynn Cooley I363 SHM 785-5067 FAX 785-3734
Administrative Director John Alvaro L200 SHM 785-3735 FAX 785-3734
MEDICAL SCIENTIST TRAINING PROGRAM
Director James Jamieson 317 ESH 785-4403 FAX 785-7446
Program Coordinator Cheryl DeFilippo 312 ESH 785-2103 FAX 785-6936
SPECIAL UNIVERSITY OFFICES
Campus Police 785-5555
Yale Shuttle Services
Student Life: http://www.yale.edu/graduateschool/studentLife/indexhb.html
University Housing Department http://www.yale.edu/hronline/gho/
Off-campus listings 155 Whitney Ave 432-9756
Graduate Apartments Manager 432-8270
Graduate Dormitories Manager 432-2167
Helen Hadley Hall 432-2140
Yale Health Service (Information & Emergencies) 432-0123
17 Hillhouse Avenue
Member Services 432-0246
Mental Hygiene 432-0290
International Center 442 Temple Street 432-6460
Office of International Students & Scholars 421 Temple Street 432-2305
Office for Women in Medicine L202 SHM 785-4860
Cushing Medical Library SHM 785-5354
Kline Science Library C8 KBT 432-3439
ITS Helpdesk http://www.yale.edu/its/ 785-3200
Academic Computing (School of Medicine) 785-5181
Yale Bookstore 77 Broadway 777-8440
Yale Telephone Directory http://scripts.its.yale.edu/cgi-bin/ph
Yale Yellow Pages http://www.yale.edu/awd/#
NEW HAVEN INFORMATION AND NUMBERS
Guide to the City of New Haven
New Haven Public Library 946-8130
Tweed-New Haven Airport 466-8833
Connecticut Limousine 1-800-472-5466 or 878-2222
Cold Spring Harbor Laboratory
Cold Spring Harbor, NY 11724 (516) 367-8346
Marine Biological Laboratory
Woods Hole, MA 02543 (508) 548-3705
Society for Neuroscience
1121 14th Street, NW
Washington, DC 20005 (202) 962-4000
THE GRADUATE PROGRAM IN NEUROSCIENCE
Policy and Personnel
The Neuroscience Track is composed of the faculty and graduate programs of the
Interdepartmental Neuroscience Program (INP) and the Department of Neurobiology.
The Interdepartmental Neuroscience Program is overseen by two co-directors who
represent the Biomedical Sciences from each end of the Yale campus. Haig Keshishian
is located at 640 Kline Biology Tower and can be reached at 432-3478. Charles Greer
is located at FMB 412 and can be reached at 785-4034. The Neurobiology graduate
program is overseen by their DGS, Amy Arnsten, who is located in B428 in the Sterling
Hall of Medicine and can be reached at 785-4431. The day-to-day functioning of the
Neuroscience Track and the Interdepartmental Neuroscience Program is handled by
Carol Russo, who is located at L200 Sterling Hall of Medicine. The Neurobiology office
assistant is located in C303 SHM and can be reached at 785-4323. Educational policy
for the Neuroscience Track and affiliated programs is decided upon and reviewed by the
INP Executive Committee, the Neurobiology DGS, and the Graduate Student Affairs
and Curriculum subcommittees of the respective programs (committee members are
listed in the appendices).
Neuroscience Track Student Committees
Each entering student is assigned an advisory committee. This committee will be
responsible for establishing the student’s course of study and for monitoring his or her
progress in the first 1-2 years. This committee will meet with the student in January and
in June and at those times this committee will provide each first year student with
written evaluation summarizing their lab rotation and their academic standing. The
advisory committee may be subsequently modified to include faculty with expertise in
the student’s emerging area of interest.
Interdepartmental Neuroscience Program Student Committees
Qualifying Examination Committee
The qualifying exam committee will be comprised of 4 faculty members from 4 different
areas of specialization from at least 2 different departments. Dr. Charles Greer, or his
representative, will sit as a fifth, non-examining member of the committee (when not
included in the original four faculty members), chairing each examination. This
committee should be formed during the second year of study; the examination must be
completed by the end of May of the second year.
Thesis Prospectus Committee
For students who have completed their Qualifying Exam and are engaged in full-time
research, a thesis prospectus committee will be formed which will consist of the
student’s thesis advisor and a minimum of 3 other ladder faculty members. At least two
formal meetings shall occur with the student and the thesis committee. The prospectus
committee will be selected by the student, but each committee must be approved by the
Directors of the Program.
Questions related to the M.D./Ph.D. Program should be addressed to the Director of the
Medical Scientist Training Program (MSTP), James Jamieson (C317 ESH; 785-4403).
However, all INP M.D./Ph.D. students will also be assigned committees made up of INP
faculty to assist them directly with their program of study.
Responsible Conduct in Science
All First Year Neuroscience Track students are required to take our Bioethics in
Neuroscience course, currently offered in the Spring semester. The INP will provide
them with copies of the required texts which are theirs to keep. Yale University believes
that all individual research and research training should be conducted in a scientifically
responsible and ethical manner. Yale’s Guidelines for the Responsible Conduct of
Research set forth the responsibilities of the faculty together with specific comments
relating to the management, date, authorship and the evaluation of the scholarly efforts
and research. This guideline builds upon information provided in the Faculty Handbook
and various University policy statements: Policy on Collaborative Research; Patient
Policy; University Policy on Academic Misconduct; and The University Policy on Conflict
of Interest. It is Yale policy to encourage research and scholarly activities essential to
the training of students, to the advancement of knowledge, and essential to the
intellectual growth of the faculty. Yale expects that scholarly activities will be conducted
with the highest ethical and professional standards. While professional standards may
vary across fields, the University has developed a set of guiding principles and policies
that are applicable to all research and scholarly activity at Yale.
T4 Additional specific policy and procedure govern the use of animals in research, the
involvement of human subjects and experimentation with radioisotopes and other
hazardous materials. All students are expected to complete required training in the
areas that affect their research.
The first 3 to 4 semesters of graduate study are spent in formal course work,
independent reading and laboratory rotations. Each student’s program of study is
designed in consultation with an advisory committee of the Neuroscience Track. This
program should both satisfy the INP and Neurobiology requirements and serve as a
good background for the thesis research.
Each student is expected to gain a broad base of knowledge in selected areas through
elective courses in Neuroscience and other disciplines. A list of Neuroscience core and
elective courses is given in the course listing at the back of this book. A complete list of
courses available can be found in the Graduate School Program and Policy Handbook,
which may be obtained from the Registrar’s office (246 Church Street) or is available in
the Program office. Students are expected to take four core courses and three elective
and reading courses to be agreed upon by their advisory committee.
REQUIREMENTS FOR THE Ph.D. DEGREE
The Neuroscience Track requires that students complete the following four
Principles of Neuroscience (NSCI 501a)
Structural and Functional Organization of the Human Nervous System (NSCI 510)
Neurobiology (NSCI 720)
Bioethics in Neuroscience (NSCI 580b)
Students must complete three additional courses from the following list, or from other
Graduate level course listings in related departments:
Seminar in Brain Development and Plasticity (NSCI 504)
Cellular and Molecular Mechanisms of Neurological Disease (NSCI 507)
Regulation of Cell Fate in CNS Development (NSCI 514)
Neuroimaging in Neuropsychiatry (NSCI 521)
History of Modern Neuroscience (NSCI 535b)
Synaptic Organization of the Nervous System (NSCI 539)
Neurophysiology (NSCI 571)
Experimental Methods in Neuroscience (NSCI 600)
Neurophysiology: Theory and Practice (NSCI 610)
Neurobiology of Learning and Memory (NSCI 614)
Foundations of Behavioral Neuroscience (NSCI 645)
Descriptions for these courses can be found on the INP website
http://info.med.yale.edu/neurosci/ and all current BBS courses can be found on the BBS
At the completion of a course, students are normally assigned a grade of Honors, High
Pass, Pass or Fail. The Graduate School requires that Ph.D. students obtain a
minimum of two grades of Honors in regular term courses by the end of the second year
of study (See Graduate School Programs and Policies Handbook). It is expected that
students will receive grades of no less than HP in any course taken for graduate credit.
Tutorials, informal seminars, research courses and term courses having fewer
than 3 credit hours cannot be used to fulfill the Honors requirement.
Laboratory rotations are considered an essential component to interdisciplinary training
and each student is required to complete a minimum of two rotations by the end of
second semester. The rotations should be in different laboratories and, preferably, in
different areas of Neuroscience from at least two departments. At least one of these
must be in the lab of an INP faculty member. The minimum duration of a rotation is one
semester or a full summer. Each rotation should be long enough to allow the student to
gain technical expertise and an appreciation of the practical aspects of an area of
Neuroscience. The laboratory rotations can serve the dual functions of broadening a
student’s background and helping in the choice of a future thesis advisor. Should a
particular laboratory not meet the needs of a student, he/she is encouraged to consider
moving to another lab. At the end of the rotation, the P.I. will complete the Rotation
Evaluation form evaluating the participation of that student in the laboratory and they will
submit this to the Neuroscience office.
The Qualifying Examination
A primary objective of an interdisciplinary program is training well-rounded students.
The qualifying examination is viewed as one means of obtaining that goal. The
Graduate School requires that “A general oral or written qualifying examination,
separate from course examinations must be passed by the student in the major subject
offered and such subordinate subjects as may be required by the department
concerned”. The INP and Neurobiology qualifying examinations involve directed
reading with faculty and a written and an oral component and should be completed
before the end of May of the second year.
The Graduate School requires that all students submit a brief outline of proposed thesis
work before beginning the seventh semester. This should be completed by the end
of May in the third year. Students will not be allowed to register for the fourth year of
study without an approved prospectus. The prospectus should consist of a written
summary of research accomplished and planned, together with a tentative title for the
thesis. This must be approved by the student's Thesis Prospectus Committee and
accepted by the Director of Graduate Studies. The prospectus should be submitted at
least 6 months before submitting the final dissertation.
Admission to Candidacy
Students who have satisfied their Program’s course requirements, laboratory rotations,
the Graduate School Honors requirement, have successfully completed the qualifying
exam, and have an approved prospectus will be formally admitted to Candidacy for the
Ph.D. degree. The Graduate School requires that this be completed before the
beginning of the seventh semester.
All INP students are required to present a public seminar of their thesis research. This
seminar is to be immediately followed by a closed oral defense of the student’s thesis
All Neurobiology students are required to have a closed oral defense with the student's
thesis research committee. If the committee finds the dissertation acceptable, the
student then must present a public seminar of their thesis research within one week of
the committee meeting.
Although the Neuroscience Track does not admit students for a terminal master's
degree, the rules of the Graduate School provide for the optional awarding of a Master
of Philosophy degree. The minimum general requirements for this degree are that a
student shall have completed all requirements for the Ph.D. except the prospectus and
dissertation. A Master of Science degree is awarded only to students who are not
continuing for the Ph.D but have successfully completed one year of the doctoral
program. The minimum requirement for this is a passing grade in at least four courses,
including two Honors grades, and completion of two successful laboratory rotations.
Students are not admitted for this degree. Students should petition for these degrees at
the Office of the Registrar (246 Church St.) by October 1 for a December award and
March 15 for a May award.
The Graduate School requires that publications based upon the dissertation results
should include a statement to that effect. For example, the author should state that the
paper is based upon:
“a dissertation submitted to fulfill in part the requirements for the Degree of
Doctor of Philosophy at Yale University”.
National funding agencies also require the following statement to be included:
“This investigation was supported by National Research Service Award #______,
from the National Institute of _________ __________”.
Other funding which the student has received (i.e. Howard Hughes, NSF, etc.) should
be similarly acknowledged.
The minimal residence requirement for the graduate school is three years; the
maximum period of enrollment for the Ph.D. degree is normally six years. Students who
have formally transferred credit for graduate work completed at another institution may
reduce the minimum residence requirement by special petition. The maximum time
may also be extended by special petition, but only if all requirements for the Ph.D.
except for the completion of research and submission of the dissertation have been
fulfilled. If you must petition for Extended Registration, please do so in a timely fashion.
Neuroscience students have a two semester TA requirement. This policy will address
how and when these requirements will best be met.
First-year students may not TA without written permission from the DGS. One semester
of teaching must be completed by the end of the third year. It is strongly recommended
that both requirements be completed by the end of the third year as students are
increasingly focused on full-time laboratory work and find it difficult to fit in TA
responsibilities at this point. If this requirement is not met by the end of the third year, a
written petition must be made to the Director of the Program and must include
information on how and when the requirement will be met.
Specifically, the first requirement must be met by teaching in either Principles of
Neuroscience (NSCI 501a), Neurobiology (NSCI 720a), Brain & Thought (CogSci 201a)
or in Structural and Functional Analysis of the Human Nervous System (NSCI 510b).
The second course may be chosen from the list of neuroscience courses listed in the
Graduate School of Arts and Sciences Programs & Policies Handbook, or from the INP
Ethics course. If not from that list of courses, the course must have approval of the
DGS. Students selected for a TA position in the Ethics course should note that two
years of teaching in this course is required for it to be counted as fulfilling one TA
As each requirement is fulfilled, the student will receive formal evaluation of progress.
First year students will receive summaries of rotation and academic standing
evaluations, second year students will receive a written summary of the Qualifying
Examination performance, which will include their current academic standing. Third
year students and beyond will receive a written summary of the prospectus and
subsequent thesis committee meetings, to be written by the PI or the committee chair,
with copies to the committee members and the INP or Neurobiology office. Each
student’s file will be reviewed annually by the appropriate program committee.
INP DEPARTMENTAL REQUIREMENTS FOR MD-PhD STUDENTS
5 courses are required, and students must obtain a grade of Honors in two of these
courses and this must be achieved in the first two years of the combined program.
Required courses are Principles of Neuroscience (Neuroscience 501a) and Structural
and Functional Analysis of the Human Nervous System (Neurobiology 500b). Three
more elective graduate level courses are required. The following courses taken during
the first two years of medical school will count towards the student's elective
requirements in the INP, provided the student has registered to receive a graduate
grade in the course: CBIO 502a, CBIO 601, GENE 500b, IBIO 530a, MB&B 800a. In
the case of students accepted into the MD-PhD Program during their first year of
medical school, a letter from the faculty member in charge of the first-year course
indicating the grade achieved in the course is required and an official transcript from the
Medical School must be submitted to the Graduate School.
2 rotations are required; rotations in another department/program will count towards this
requirement upon approval of the INP Director of Graduate Studies.
MD/PhD students are required to TA one term, two terms are preferred. Previous
teaching (as TA) in the histology labs or courses in MCDB does count toward this
requirement as long as the student has taught while enrolled at Yale as an MD/PhD
MD/PhD students must complete their qualifying exam before the end of their first year
as an affiliated graduate student. Thus, if the student affiliates at the customary point of
year 3.5 (beginning of the Spring semester of the third year of matriculation at Yale),
they must complete the examination before registering for the Spring semester of the
fourth year at Yale.
MD/PhD students must complete and submit their thesis prospectus by the end of the
second year as an affiliated graduate student. Thus, if the student affiliates at the
customary point of year 3.5, they must submit the approved prospectus before
registering for the Spring semester of the fifth year (at the beginning of year 3 as an
affiliated graduate student).
Please note that every thesis prospectus MUST be approved by the thesis
Admission to Candidacy:
MD/PhD students are required to have been admitted to candidacy by the end of the
second year as an affiliated graduate student. Generally, the submission of the thesis
prospectus is the final requirement for admission to candidacy and paperwork for both is
submitted to the Graduate School at the same time.
All graduate students who are admitted to candidacy are required to have an annual
thesis committee meeting. All graduate students are required to give a student
research presentation annually and are expected to attend rotation/student research
talks as well as INP-sponsored journal clubs.
Affiliation requirement: A copy of the student’s application to the MD/PhD program, a
copy of the student’s current transcript and notation of rotations completed must be
submitted to the INP office. The DGS must have this information in hand before the
official MD/PhD student affiliation form can be approved.
Year One: MD/PhD students complete courses in the Medical School and register for
selected courses in the Graduate School. Most who identify Neuroscience as their
probable PhD field will take the required course, Principles of Neuroscience, in the fall
semester. This is the recommended timing. MD/PhD students should take
Neurobiology 500b in the spring for graduate school credit/grade. Other electives as
listed above may be taken for graduate school credit to fulfill our requirements and
indeed, it is recommended that this be done. Two laboratory rotations should be
completed in the summer. The DGS and the Neuroscience Office may be of assistance
in identifying appropriate laboratories based in the student’s interests.
Year Two: Courses in the Medical School are typically taken. Part 1 of the Boards is
Year Three: By January of the third year, a thesis lab should be identified and all
paperwork should be completed (affiliation form completed and copy of student’s
academic record including application transferred to Neuroscience Office). Student’s
stipend is supplemented by PI/PI’s primary department at time of affiliation.
Year Four: Qualifying Examination must be completed within one year of
laboratory/program affiliation. This is a graduate school rule and graduate school
registration for the following semester may be held up if this requirement is not fulfilled
in a timely manner. Typically this will be fulfilled before the Spring Semester of the
Year Five: The Thesis Prospectus must be approved and submitted to the Graduate
School by the end of the second year of laboratory/PI affiliation. Typically, this is by the
end of the Fall Semester of Year Five. Registration for the following semester may be
held up if this requirement is not fulfilled in a timely manner. The Thesis Committee
approves the prospectus and required paperwork is then delivered to the INP office by
the student. The INP office will then complete the Admission to Candidacy paperwork
and submit it to the Graduate School. The Prospectus must be submitted to the
Graduate School at least six months before the dissertation is submitted.
Year Six: Typically an MD/PhD student will complete and defend their dissertation at
the end of the Fall semester or the beginning of the Spring semester. We require that
MD/PhD students defend their dissertations before returning to fulfill the remaining
Medical School requirements.
Year Seven: Student completes all remaining requirements and graduates in May.
While this is considered a guideline for a typical MD/PhD student, we recognize that not
every student will follow this path. Any digression from this timeline must be discussed
and approved by the DGS, with appropriate notes to the student’s file and copies to the
MD/PhD office. Continued participation in the INP is subject to the satisfactory
completion of requirements in a timely fashion and if any question arises about the
satisfactory progress of a student and the qualifying examination committee or the
thesis committee cannot agree on an appropriate resolution, then the INP Executive
Committee will have the authority of the INP faculty to determine a course of action.
PROCEDURES FOR THE QUALIFYING EXAMINATION,
THESIS PROSPECTUS AND DISSERTATION
During the second year, each student will choose a qualifying examination committee,
which is to be comprised of four faculty members from at least two different
departments representing four different areas of specialization. Dr. Charles Greer or his
representative will chair each committee. He may also act as both a fourth examining
member and chair.
Each of the four faculty members, in discussion with the student, will select ten -fifteen
important papers from their field of specialization that the student will read, study and
discuss with the faculty member. It is recommended that the student meet on a regular
basis with each faculty member to discuss the assigned papers over a six week period.
A typical scenario would involve a minimum of four to six sessions with each faculty
No later than three months after receiving the papers, each committee member will
prepare two essay questions based upon the readings. These eight questions will be
presented to the student, who will select three questions representing three different
areas of specialization. After the list of eight questions has been presented to the
student, the student will have forty-eight hours to answer the questions. Library and
literature resources will be available and the student may complete the exam in the
location of their choice. Any one of the answers should not exceed the equivalent of
three type-written pages single-spaced; references may be included at the discretion of
No later than one week after the written exam is completed, an oral examination will be
held with the student and the members of the committee. An oral examination focusing
on the readings will be held with the student and the members of the committee.
As described above, the Qualifying Examination has three parts, all of which are
evaluated. The student’s performance in meetings and discussions with faculty
committee members, the written examination, and the oral examination are assessed
when the committee members are all present for the oral examination.
The qualifying examination must be completed by the end of the second year. The
exam should be completed by the end of May of the second year. Exemption from this
deadline requires the approval of the INP Executive Committee. If a student fails the
Qualifying Exam they can be terminated from the Program upon agreement of the
Qualifying Committee. At the discretion of the committee, the student may be offered a
second attempt at the Exam. If so, then a new committee will be formed by the Director
of the Program.
Students in Neurobiology are expected to take their Qualifying Examination by the end
of the second year. The student chooses 4 faculty members - 2 related to
molecular/cellular neuroscience and 2 related to systems/integrative neuroscience - to
perform directed readings. The student and faculty member should choose 15-25
papers on a defined research topic. Ideally, the student should meet weekly for 4 - 8
weeks with the faculty member to discuss the papers in detail. Research advisors
should be aware of the great commitment expected during the qualifying examination
and permit students to greatly reduce their time in the laboratory during the preparation
process. The qualifying Examination has 2 parts: a written and oral exam. The written
exam is carried out over 2 days. The student is given 2-3 questions on each research
topic; the student chooses one question per topic and has 3 hours to respond to each
questions. The written exam is open book. The written responses are distributed to the
faculty members and read prior to the oral exam, which occurs within 1 week of the
written exam. The student is asked to choose 1-4 additional faculty members to attend
the oral exam as "readers"; they will read the answers and participate in the oral exam.
The Director of Graduate Studies for Neurobiology is also in attendance at the oral
exam. The oral exam usually lasts about 2 hours, and is used to fortify or elaborate on
the written exam. Students who perform exceptionally well on the Qualifying Exam can
pass "with Distinction". Students who fail the exam are allowed to take it over one more
time; if this performance is not satisfactory students are required to leave the program
with an M.S. degree.
Thesis Prospectus - INP and Neurobiology
Prior to the writing of the thesis, the student will attend at least 2 formal meetings with
the thesis advisor and a committee of a minimum of 3 additional ladder faculty
members. Typically, the thesis advisor will chair the meeting, although the committee
can select another member to act as chair at this time. Two weeks prior to the first
meeting the student will distribute a short document of no more than 10 pages which
includes a brief introduction to the problem(s) being studied, the techniques being
employed and a short discussion of potential outcomes and/or pitfalls. This document
should be modeled on the NIH NRSA Predoctoral fellowship guidelines and students
are encouraged to submit the final document for consideration by NIH. The first
meeting of the thesis committee must occur prior to the end of the third year. It is
strongly recommended that this meeting occur early in the third year as to gain the
maximum benefit from the committee members in the design of the thesis project. The
student will make a concise presentation to the committee and then this meeting should
address the strengths and weaknesses of the proposed research. The thesis
prospectus must be approved by the committee and the Program Director and
submitted to the Graduate School by May 30 in partial completion of the requirements
for admission to candidacy for the Ph.D. degree. The student must be admitted to
candidacy to be eligible to register for the seventh semester. The second and all
subsequent committee meetings will take the form of an interim progress report in which
the student makes a presentation of progress to date and the committee discusses the
progress and/or problems relevant to the thesis. The PI or chair of the committee will
write a summary of the meeting using the form available from the INP website which will
be copied to the committee members, including the student. A copy must also go to the
INP or Neurobiology office. We expect each student's thesis committee to meet at
least once a year, more often if necessary.
It is expected that the thesis prospectus committee will also serve as the final thesis
defense committee. Changes in a student’s thesis committee require approval of the
Directors of Graduate Studies. It is expected that the student will be in continual
communication with the thesis committee during completion of the research and
preparation of the written document and, again, at minimum, formal committee meetings
must take place annually, with documentation of completion to be forwarded to the
Neuroscience or Neurobiology offices.
Dissertation and Defense
During the final stages of thesis research, the student should maintain especially close
communication with the thesis advisor and committee in order to most effectively
establish the content and composition of the dissertation. As the dissertation nears
completion to the satisfaction of the thesis committee, a date for the defense should be
scheduled by the student and the committee in consultation with the Directors. No later
than two weeks before the defense is to take place, the “final” draft of the dissertation
shall be distributed to the committee members. The thesis committee will consist of 4
members, including the thesis advisor and 3 additional faculty members from at least
two different departments. An outside reader (outside the University) is optional and is
not required by the Graduate School or the INP. A committee chair other than the
thesis advisor will be appointed by the committee members if this has not already
occurred. However, the thesis advisor may be an active participant during the defense
and may ask questions or reformulate questions asked by other members of the
committee or may act as an advocate on behalf of the student. The thesis advisor will
remain present during the committee deliberations at the conclusion of the thesis
The thesis defense consists of two parts: 1) An open seminar to which all members of
the academic community will be invited; and 2) An oral defense of the thesis, which will
include only the student and the thesis committee. The oral defense should not exceed
two hours. When the defense has been completed, the student will leave the room and
the committee will discuss acceptance of the thesis (with or without revisions) or
remand it to the student for further work. Once all changes have been made to the
satisfaction of the committee, each committee member will submit a written report and
recommendations to the Graduate School and the Directors, who will approve the
award of the Ph.D.
The Dissertation and Defense in Neurobiology are similar to that in the INP, with the
exception that the oral defense of the thesis with the thesis committee occurs prior to
the open seminar. The public seminar is only given if the thesis committee has
approved the dissertation, and should occur within one week of the committee's
The student must inform the Graduate School of his/her intent to petition for the Ph.D.
degree (by March 15 for a May award; October 1 for a December award) after the thesis
has been successfully defended. This petition includes 1) an unbound copy of the final
draft of the thesis (due at the beginning of October for December degrees, March 16 for
May degrees); 2) soft-bound copies of the final draft of the thesis which the Graduate
School will send to the committee members, along with the formal evaluation forms
which the committee members will complete and return; and 3) The INP office will
complete and submit the Notification of Readers form - the list of names and addresses
of the committee members.
All students in residence or in absentia are required to register with the Graduate
School. Failure to do so will result in ineligibility to use University facilities, including the
Libraries and the Health Services.
Students are normally given the first week of classes to register (see the Calendar for
dates http://www.yale.edu/bulletin/html/grad/introduction.html#Calendar). Online
Course Selections are due September 20. Some changes can be made after this
(consult the Graduate School Registrar for details), but a $25.00 fee will be charged for
each change. Formal registration takes place in the Neuroscience Program Office,
L200 SHM. Continuing students (those who have completed the 4 year full-tuition
requirement) must also complete the Online Course Selection to ensure their
Continuous Registration for the next academic year. Online Course Selection and
Instructions for same are found here: http://www.yale.edu/sfas/registrar/
Students who wish to maintain the option to use University facilities and all students
supported on Yale-administered funds during the summer months must also register
with the Graduate School. This applies whether or not the student will actually reside in
New Haven. There is no fee for summer registration if a student has been registered
during the preceding academic year. Summer registration must be completed at the
Registrar’s Office (HGS or 246 Church) in June.
Foreign Student Registration
Foreign students must register at the Office of International Students and Scholars (421
Temple St.) before registering with the Graduate School. Foreign students are strongly
encouraged to use this office as a resource for any problems related to their foreign-
In Absentia Registration
Students whose circumstances require full-time study at another institution, or
dissertation research on a full-time basis outside the New Haven area can register in
absentia provided he/she receives prior written approval of the Program Directors and
the Dean of the Graduate School. Students who register in absentia do not qualify for
Yale Health Plan services unless they are paying full tuition, but may enroll themselves
and their dependents at full cost.
Leave of Absence
A student in good standing who wishes to interrupt his/her study temporarily for
personal reasons (i.e. maternity leave, financial necessity, health problems or other
extenuating personal circumstances) may, with approval of the Directors and the Dean,
be granted a leave of absence of up to one year for students who have successfully
completed one year of study and two years for students who have been admitted to
candidacy for the Ph.D. degree. Students on leave may not engage in full-time degree-
related activities during the period of leave. However, students may participate in full-
time teaching or other full-time employment or pursue training for a special skill while on
leave of absence. Students on leave of absence need not apply for readmission before
returning to Yale. However, to be considered for financial aid in the year following a
leave of absence, students must submit a formal application to the Program by
February 1 of the year preceding return. Students on leave will not be enrolled in the
Yale Health Plan but may continue membership by paying full fees.
Full tuition is charged to all Ph.D. students for 8 semesters, except in the case of
students who have completed all degree requirements (including submission of the
dissertation) in less than four continuous years from the date of entry into the Ph.D.
program. After eight semesters, the student must continue registering until the
dissertation is submitted or the terminal date is passed. The fee for continuous
registration is currently $ 293 per term.
Tuition charges for students who are considering leaves of absence or registration in
absentia should be arranged in consultation with the Graduate School.
Sources of Support
For the 2006-2007 year, all students will receive tuition plus a stipend of $27,000 (12
months). The most common sources of support are:
1. U.S.P.H.S. National Research Service Awards: Each year, the National Institute of
Health (NIH) provides Yale with funds for graduate student tuition and a stipend
($20,772 for the ‘06-‘07 year). The Graduate School and/or the Medical School
provides students with a stipend supplement. These awards are available for a
maximum of 4 years. There is no "Payback" obligation for pre-doctoral support.
2. External Fellowships: Several external fellowships which are administered by
federal or private sources are also available to graduate students in Biomedical
Sciences. A list of these awards is available on the INP website or with the Assistant
Dean of Biomedical Sciences (HGS, 432-2744). Students are encouraged to refer to
this list regularly to determine required qualifications and application deadlines. The
INP and Neurobiology programs strongly encourage students to apply for any outside
fellowships, and in particular those awarded by the National Science Foundation, the
Department of Defense and the Homeland Security Office. More senior students are
encouraged to submit Predoctoral NRSA applications. Information for these awards are
available in the Program offices. Most applications are now completely online and links
are available on the INP website.
3. University Fellowships: These fellowships are awarded by the Graduate School
and/or the Medical School.
4. Research Assistantships: Research grants and contracts awarded by outside
agencies to support the research projects of individual faculty members may provide
funds for Research Assistantships for graduate students. These appointments are
decided by faculty negotiation. In most cases, these appointments are given to senior
students who are engaged in full-time dissertation research in the laboratory of the P.I.
granting the funds.
The Graduate and Professional student payroll runs on a semi-monthly schedule of
payments (the 15th and last business day of each month). Checks can be deposited
directly into any bank account at the request of the student. See Carol in the INP office
for Direct Deposit set-up or change of address.
For information on the various types of graduate student loans, consult the Financial Aid
Office (125 HGS; 432-2739).
First-year and unaffiliated second-year students are provided with $800 in travel funds
for use towards one scientific meeting per year. See the INP Office to make
arrangements for this. Students are encouraged to attend the Society for Neuroscience
annual meeting in the fall.
LECTURES, SEMINARS AND JOURNAL CLUBS
Yale graduate students in the Biomedical Sciences have access to a large number of
relevant research seminars, journal clubs, retreats and symposia. The programs of the
Neuroscience Track sponsor the following events, which students are expected to
The INP seminar series provides an opportunity for students and post-docs in the
neuroscience community at Yale to interact on a one-to-one basis with visiting
neuroscientists in an informal setting. The seminars are held monthly, on the second
Tuesday of the month, September through June in the Medical School. Neuro students
select the speakers, drawing from the fields of cellular and molecular neurobiology,
neurophysiology, developmental neurobiology, and systems/computational
neuroscience, and make the invitations themselves. A student host coordinates lunch
with interested graduate students and the speaker. Following each seminar, graduate
students and post-docs are invited to have dinner with the speaker. Contact the INP
office for additional information. Announcements are sent each month.
The Neurobiology series is usually held monthly on Thursdays at noon in SHM I304.
Neurobiology students and postdocs invite speakers from a variety of disciplines.
Students and postdocs are invited to have lunch with the speaker after the seminar.
Each speaker is assigned a student or postdoc host, who may also join the speaker for
The INP student-directed journal club brings together graduate students and post
doctoral fellows in the neurosciences to discuss current papers in the field. Members
meet on a biweekly basis and take turns in leading the discussions. The Journal Club is
an excellent opportunity to practice presenting papers in a congenial and collegial
atmosphere, to keep apprised of neuroscience research and to maintain contact with
fellow students, events and research within the expansive Yale neuroscience
community. Anyone with an interest in neuroscience is invited, but members are
encouraged to attend regularly. Announcements are sent for each scheduled date.
The paper to be presented is always available on the INP website prior to the Journal
The Neurobiology Journal Club coordinates with the Neurobiology Seminar Series.
Students meet monthly prior to a Seminar to discuss several papers from the speaker's
lab. Students discuss the papers over lunch in an informal atmosphere. These
discussions can be particularly helpful in learning about research outside one's field.
Club Neurobiology is sponsored by the Section of Neurobiology and is intended to serve
as an informal forum for members of the Neurobiology community to interact. In
particular, seminars are presented by post-doctoral fellows from Neurobiology labs.
Club Neurobiology is scheduled the third Tuesday of each month, throughout the
academic year. This seminar series is held in SHM B145, dinner and drinks are
available at 5:00 pm, with the seminar beginning at 5:30 pm.
Spike Club (http://jacknife.med.yale.edu/spikeclub/) is a student organized journal club
that reviews recent papers in systems neuroscience. Meetings are held every other
week at noon in the Dome Room (SHM C-500). A delectable lunch from one of New
Haven's finest dining establishments is served. We wish to thank the Yale
Interdepartmental Neuroscience Program and the Swartz Initiative for Theoretical
Neuroscience at Yale for their generous support. Future meetings will be supported by
the Swartz Initiative, and the journal club will reflect such interests.
Synaptic Transmission Journal Club meets Fridays at noon, alternating with Spike Club.
Developmental Biology Journal Club meets on occasional Thursdays in the Child Study
Graduate Student Seminar Series
To maintain regular interactions among the student body, INP students participate in a
regular “In Progress” seminar series. At these seminars, students make short
presentations of research-in-progress to Neuroscience students and faculty. This gives
graduate students a unique opportunity to have their work evaluated by their peers and
Second year students coordinate the scheduling of this series and are in charge of
providing lunch for everyone.
Guidelines for these presentations are as follows:
• Talks should consist of a clear and well organized presentation of the background
and rationale for the research, and the recent findings. Plan a ten or twenty minute
talk and allow a further five or ten minutes for discussion, which may occur at any
time during the talk or after.
• Begin your talk by introducing yourself and announce in whose lab you are working.
For clarity, you should make sure that the first few overheads or slides give
adequate background for your presentation. Your audience is quite diverse. After
giving the background, then go through your data, presenting it in as clear a fashion
as possible. Pay attention to the order in which you present your information and to
the manner in which your data slides or overheads are set up. Make sure you
arrange the data in a fashion that is logical and easy to interpret. This will avoid
confusion and save time. End by clearly stating your conclusions. Practicing your
talk in front of a mentor, members of your lab, and/or a few friends is a good idea.
• First and second year students are often nervous about giving these seminars
because they feel they do not have sufficient data. This should not be a concern.
Use the opportunity to practice presenting. These talks should be no more than 10
• More senior students should focus on the more recent experiments. Do not try to
gloss over problem areas. Remember that a primary function of these seminars is to
get feedback from your colleagues. Someone in the audience may have an idea
which could help, and you should encourage such ideas to come out. These talks
should be twenty minutes.
Other opportunities to present
Neurobiology students have the chance to present their thesis research as an informal
seminar to the other students and faculty. Seminars usually occur monthly in the
mornings over coffee and pastry. The seminar series is an excellent opportunity to
learn about public speaking in a friendly environment.
Annual Interdepartmental Neuroscience Program Retreat
This annual weekend meeting is open to all members of the Yale Neuroscience
community. It features seminars by faculty and an afternoon poster session. There is
also ample time for informal discussion to enable conferees to become acquainted with
current Neuroscience research on the Yale campus as well as opportunities to interact
with students, postdoctoral fellows and faculty from all areas of neuroscience at Yale.
Other Seminar Series of Interest
Department Day Time Location
Molecular Psychiatry (BSTP) Monday 3:45 pm 133 CMHC
John B. Pierce Seminar Monday 4:00 pm JBPierce Lib.
Child Study Center Grand Rounds Tuesday 1:00 pm Cohen Aud
Clinical Neuroscience Grand Rounds Wednesday 8:00 am Brady Aud
Biology Department Seminar Wednesday 4:30 202 OML
Cell Biology Seminar Wednesday 12:30 C429 SHM
Current Work in Behavioral Neuroscience Thursday 3:30 pm 100 AKW
Cellular & Molecular Physiology Seminar Thursday 4:00 B147 SHM
Molecular Biophysics and Biochem. Seminar Wednesday 4:00 OML/BASS/Hope
Neurobiology Thursday 12:00 I304 SHM
Pharmacology Seminar Thursday 12:30 Giarman Room
Psychiatry Grand Rounds Friday 10:15 am CMHC Aud.
OFF-CAMPUS NEUROSCIENCE COURSES
Neuroscience students are encouraged to take advantage of the several Neuroscience
Summer and Short Courses which are offered in various regions. First and second year
students must have permission from a Neuroscience Program Director to apply for
these courses. Although many summer courses are offered internationally, those
offered by the Marine Biological Laboratory (Woods Hole, MA) and Cold Spring Harbor
Laboratory (Cold Spring Harbor, NY) are among the very best. Course listings can be
found on the home pages of these institutions.
Marine Biological Laboratory, Woods Hole, MA
(508) 289-7401, email@example.com, http://www.mbl.edu
Cold Spring Harbor, Cold Spring Harbor, NY
(516) 367-8345, firstname.lastname@example.org, http://www.cshl.org/
CAMPUS FACILITIES, MISCELLANEOUS INFORMATION
The main Yale campus libraries of interest to Biomedical students are:
1) The Medical Library (SHM) Hours: M-Th 8:00 am-midnight; F 8:00 am-10:00 pm; Sat
10:00 am-7:00 pm; Sun 11:00 am-midnight.
2) The Kline Science Library (C level, Kline Biology Tower) Hours: M-Th 8:30 am-
midnight; F 8:30 am-9:00 pm; Sat10:00 am-7:00 pm; Sun1:00 pm-midnight.
Both of these libraries have access to Interlibrary Loans, and can obtain periodicals and
papers from other libraries across the United States. Rare books from Yale Libraries
are stored in the Seeley Mudd Library (38 Mansfield St.; 432-3203). Books can be
delivered by courier to other libraries on request.
New Neuro students will be given information regarding photocopying privileges at the
orientation meeting. These privileges are extended until you have settled into a thesis
lab. All campus libraries have photocopying machines for use on either a cash or
charge basis. The libraries will also copy documents on request, but this can become
both costly and time consuming. Be sure to inquire about the time and cost
requirements before submitting a request for photocopying to any of the Yale libraries.
Bulk copy, if arranged for easy management, can also be done by the Copy Center,
which is located at 127 College Street (785-4675). Outside commercial copiers are also
available in many locations adjacent to the campus.
The McDougal Graduate Student Center
McDougal Center- Hall of Graduate Studies (HGS), 320 York Street (432-8273,
email@example.com, www.yale.edu/mcdougal). At Yale, there is no general
campus center, student union, or student center for the entire University community. For
graduate students, much of student life is based in their respective departments and
schools, and dormitories or apartment complexes. The McDougal Center is a place
where graduate students from across the campus regularly meet and share interests.
Mission- A generous gift from Mr. Alfred McDougal, a Yale alumnus, and his wife, Ms.
Nancy Lauter, enabled Yale in 1997 to create the McDougal Graduate Student Center.
The McDougal Center provides space and program funding for building intellectual,
cultural, and social life, and for facilitating professional development activities across the
departments of the Graduate School of Arts and Sciences. The McDougal Center
warmly welcomes the participation of students from other Yale Graduate and
Professional Schools, postdoctoral fellows, faculty, staff, alumni/ae of the Graduate
School, and members of the larger Yale community. Its web site
(http://www.yale.edu/mcdougal) provides all kinds of information relating to graduate
student life. The Center provides members of the graduate student community with a
place of their own on campus.
Facilities-The facilities of the McDougal Center enhance student life in many ways. The
magnificently restored Common Room has been transformed into a lounge with
comfortable furnishings, internet ports, newspapers and magazines, and a student-run
cafe serving coffee and light food throughout the day. In an adjacent wing on the first
floor of HGS the Center has a large multi-purpose Program Room (HGS 119) with a
stage, seating for up to 100, and advanced video and sound projection equipment. The
Program Room provides space for lectures, conferences, performances, film series,
workshops and other events by and for students. The Center also has smaller
conference and meeting rooms. Graduate student groups and departments may request
to reserve space by contacting the center office at 432-8273, stopping by HGS 123, or
filling out a request on line at www.yale.edu/mcdougal/mcdougal/roomform.htm. There
is a public computer cluster supported by ACS, a public copy machine, a public phone,
bulletin boards and information kiosks as well. The lower floor also offers offices for the
Assembly of Graduate Students, graduate student organizations, rooms for Teaching
Fellows to meet with students, lockers for graduate student use and vending machines.
The McDougal Center is open days, evenings, and weekends.
Student Life Programs - Lisa Brandes, Director, 123 HGS, 432-8273. The Center offers
a variety of activities open to the G&P community. These include weekly movies on the
Really Big Screen, coffeehouse musical evenings, happy hours, poetry readings,
student research presentations, health and wellness workshops, teas with campus and
community figures, and service opportunities such as blood drives. It hosts activities
organized by student groups and departments, including cultural festivals, movies,
lectures, receptions, and conferences. Activities are publicized in campus publications,
in McDougal Notes calendar, on the web site, and via email lists.
Graduate Career Services (GCS) -123 HGS, 432-8896, www.yale.edu/gcs. Graduate
Career Services was established to guide and educate graduate students about
academic and non-academic career opportunities and job search strategies. The office
offers programs such as professional career development workshops, seminars,
resume/CV reviews, individual counseling, on campus interviews, dossier service and
current job listings.
The Office of Teacher Preparation -123 HGS, 432-8896. This office directs the teacher
preparation program within the McDougal Graduate Student Center, and also works
with faculty and graduate students to enhance teacher preparation programs in
departments. They advise the Working at Teaching program. The mission of Working
at Teaching (www.yale.edu/wat) is to help improve the teaching skills of Yale graduate
students and to contribute to their professional development as teachers. WAT offers
excellent peer-led training workshops for teaching assistants each semester, promotes
dialogue in the Yale community about all aspects of pedagogy through forums and
lectures, and supports teaching assistants by publishing a handbook, maintaining a
resource office, and conducting classroom visitations. WAT is sponsored by the
Graduate School and is housed in the McDougal Center. While most of the students
who participate in WAT programs come from the Graduate School, other G&P students
who teach take part in its activities.
Resource Library for Fellowships, Careers, and Teaching (formerly the Fellowship
Library)- B44 HGS, McDougal Center, www.yale.edu/mcdougal/resource This is a self-
service reference library intended to assist Yale graduate students, postdocs, and
faculty in finding fellowships, pre-dissertation, dissertation, travel and research funding.
(Teacher training and career services books are being added). It contains a physical
site (Room B44) of grant and funding books, announcements, and files on programs
and topics, and a virtual site of links, announcements and searchable databases. For
room access, check out the key from the Center office, Room 123 HGS, or ask the night
program attendant on duty to let you in. Handouts and the web can explain to you how
to use the materials, but the actual research is up to you.
Graduate Student Organizations
The Graduate Student Assembly (http://www.yale.edu/assembly/) The Graduate
Student Assembly (GSA) is the elected body of Yale students in the Graduate School of
Arts and Sciences.
The Assembly's goals are to:
• identify the needs and concerns of graduate students, consider possible
solutions, and present these to the Dean and other administrators.
• discuss and advise on changes to Graduate School policy proposed by the
• provide a means for communication and deliberation both among graduate
students and between grad students and other members of the university
The Graduate Student Assembly meets every other Wednesday in the Hall of Graduate
Studies (HGS) room 119 at 7pm. Meetings are open to all Graduate Students.
Conference Travel Fund
The Conference Travel Fund aims to support the professional development of graduate
students by providing financial assistance to present papers and posters at conferences
on a competitive basis. Conference funds are disbursed three times per year with
application deadlines on October 15th, February 15th and May 1st.
Applications for the February 15th, 2007 cycle will be accepted from January 15 -
February 15, 2007.
The Graduate-Professional Student Senate (GPSS) is a university-wide organization
representing the interests of all graduate and professional students and provides a
means of voicing concerns to the University administration as well as to the various
departments and schools. http://www.yale.edu/gpss/Senate/aboutus.html
The Graduate Employees and Students Organization (GESO) was founded in 1990 with
the purpose of achieving negotiated agreements with the University Administration,
including conditions of graduate student employment and life.
The Graduate and Professional Student Center at Yale (GPSCY) provides a central
meeting place for graduate and professional students, faculty and alumni. Open only to
members and their guests, the GPSCY operates a full service bar with reduced prices,
sponsors receptions, dances and parties and hosts conferences, rehearsals and
There are many other formal student organizations at Yale, covering a broad spectrum
of interests and activities including an active graduate-professional intramural sports
For students who feel they have been treated unfairly in some capacity by an individual
or group within the University, several courses of action are available. First, the advice
of the thesis advisor, the Graduate Student Affairs Committee or either of the Program
Co-Directors may be sought. Alternatively, if the matter is one which is not appropriate
to raise within the Program administrative structure, other University agencies may be
contacted, which include: 1) The Dean of the Graduate School (Jon Butler -112 HGS;
432-2733); or 2) The Deputy Provost (Stephanie Spangler - 137 HGS; 432-4446),
whose office is especially concerned with matters relating to equal rights for minorities
and for women. The Office for Women in Medicine can also be contacted. It is located
in L202 SHM; 785-4680. In addition, the Dean of Graduate Studies has appointed a
standing Grievance Committee to receive and review student complaints of sexual
harassment. This Committee is comprised of six members (2 faculty; one member of
the Graduate School Administration; two students; and one counselor). Students may
bring questions about procedure, seek informal advice, or present a complaint to any
member of the board, either orally or in writing.
Yale Health Plan
The Yale Health Plan (YHP) is a comprehensive health care program, located at the
University Health Care Services Center (17 Hillhouse Avenue) which is available to all
faculty, students and staff. All Yale students who are enrolled in graduate study at least
half-time are automatically members of the YHP and are eligible for ambulatory care
services and the use of the infirmary at no additional cost. Yale requires that students
have hospitalization coverage as well. For all graduate students who do not have
hospitalization from another source, this coverage will be provided at no cost to the
student. There is also supplemental coverage for prescriptions, eye care and other
services. This coverage must be paid for by the student, the program does not cover
this. If NOT WANTED, each student must sign a completed waiver form every year and
forward it to the YHP by September 15.
Students may also enroll their spouses and dependents by filing an application with the
YHP. The Graduate School will pay for half of this fee. The rest of the fee is applied
through the Bursar’s office. Only those spouses and dependents specifically enrolled
are eligible to receive YHP benefits and services. In addition to primary and emergency
care, a full range of specialty services are available, including Allergy, Dermatology,
Otolaryngology, General Surgery, Mental Hygiene, Neurology, Obstetrics and
Gynecology, Ophthalmology, Orthopedic Surgery, Optometry, Contact Lenses and
For first-year students, YHP membership begins on the first day of registration. Prior to
registration, a complete medical examination form and health report must be submitted
to the YHP. If these forms are not available, YHP will provide the necessary
examinations, and will bill the student a $25 charge. Additional information can be
obtained by contacting the Member Services Office at 432-0246.
Several University dining facilities are maintained for the convenience of students,
faculty and staff. In the Medical School and Science Hill areas, these include:
1. Marigold’s (367 Cedar St., adjacent to SHM).
2. Yale-New Haven Hospital Cafeteria (Main – 1st
floor of the Hospital)
3. Yale-New Haven Hospital Cafeteria (2nd floor of the Clinic Building, 330 Cedar St).
4. Kline Biology Tower Cafeteria (12th floor, KBT)
5. School of Organization and Management Cafeteria (135 Prospect St.)
6. Hall of Graduate Studies Cafeteria (York Street)
Schedules and routes can be found here:
The Yale Shuttle Bus is a campus-wide service operated by the University. The Shuttle
runs every 20 minutes during peak hours, and every 40 minutes for the remaining time,
starting at 7:20 a.m. until 6:00 p.m. The Shuttle is free with a valid Yale identification
card, or $.65 without. Schedule information is also available in SHM CE 1 or at the
Parking Service Office, Hendrie Hall, 165 Elm St.
Medical School Shuttle Service 203 785-5555: Between the hours of 5:00 p.m. and 6:00
a.m., Monday - Friday, the service provides scheduled and unscheduled pick-up of Yale
University students and staff within the boundaries of the Medical School.
Yale Minibus (Nighttime) 203 432-6330: Buses run from 6:00 p.m. to 7:30 a.m. Monday
through Sunday (seven nights a week). This service runs on a scheduled route around
the campus and also takes dispatched calls for off-route pickups. From 1:00 a.m. to
7:30 a.m., service is available on call-in basis only. Dial 2-6330 from any campus phone
In addition to these services, the University Police provide transportation 24 hours a day
for medical emergencies to the University Health Services. Call 432-4400 for this
Parking is available in various locations around campus on both a regular and a special
service basis. Inquiries and applications for permits should be directed to the Medical
School Parking Office, Basement of SHM (785-4201) for the Medical School Area or
the Office of Parking and Transit Services, 155 Whitney Ave (432-9790) for the Science
Yale Security emphasizes that the campus is not immune to crime, property loss or
personal injury. Individuals are urged to walk in groups, or request to be escorted by
the Student Patrol Service which has been set up by the University Police to provide for
safety on the streets and in the parking lots. Night-time transportation is available for
students working late in the evenings.
During registration, incoming students will receive an identification card for access to
campus facilities. In case of a lost or stolen ID card a new ID can be issued for a fee at
the Medical School Support Center (CE 1 SHM) 9:00 a.m.-12:00 p.m., Tuesdays.
All neuroscience students can be reached by email. Use the generic Yale address
format of firstname.lastname@example.org.
Faculty - All neuroscience faculty can be reached by email. Use the generic Yale
address format of email@example.com.
Each incoming graduate student is set up with a free computer account, including email
access. Username and PIN number are sent to incoming students in the summer. This
account gives you access to the Internet, MedLine, ORBIS, etc.
Most areas on campus are now accessible by swipe-access with your current ID.
Departmental keys (for labs, etc.) should be obtained through the specific department’s
New students may have their mail sent to of the INP office, where it will be held for pick
up, or forwarded to the department in which the student is currently working.
Neurobiology students have mailboxes across from C303 SHM
In the Medical School area, there is an ATM and Bank of America branch at 330 Cedar
Street, between the Clinic Building and FMB on the first floor (go to the Information
Desk and turn left). There is another ATM located on the the main floor of the hospital.
1. University Athletic Facilities are available for standard fees. They include:
a. Payne Whitney Gymnasium (70 Tower Parkway; 432-1444), for sports, dance,
exercise and swimming.
b. Ingalls Skating Rink (73 Sachem Street; 432-4771) for ice skating sessions
between mid-October and April.
c. The Yale Golf Course (Ray Road; 432-0895).
d. Cullman Tennis Courts (for indoor tennis, late October through late April) and
outdoor courts (Derby Avenue; 432-0693).
e. The Yale Sailing Center (Short Beach, Branford; 488-9330), which has
equipment available for rent and offers sailing lessons.
f. Outdoor Education Center (East Lyme, Ct.) Call 432-2492 for info.
2. Musical Opportunities/Activities include:
a. The Yale Symphony Orchestra, which is comprised of students from all levels
within the University.
b. A variety of choral groups, encompassing several musical styles. For more
information, contact the Music Department at 432-2986.
c. The Yale School of Music sponsors frequent recitals, which are listed in the
Weekly Bulletin & Calendar.
d. The New Haven Symphony Orchestra and the Woolsey Hall Concert Series.
Tickets are available at the New Haven Symphony Office, 33 Whitney Avenue.
3. Theatrical Productions
a. The Yale Repertory Theatre (Chapel and York; 432-1234)
b. The Long Wharf Theatre Company (222 Sargent Drive; 787-4282)
c. The Yale Cabaret (217 Park Street; 432-1566)
d. The Shubert Theatre and The Palace Theatre (College Street)
4. University Museums
a. The Peabody Museum of Natural History (Sachem & Whitney; 432-5050),
Exhibits of the natural history of the New England area, with extensive collections
in geology, anthropology and ornithology. Displays include minerals; birds of
Connecticut; fossil plants, fish, birds, reptiles and mammals; and, of course,
b. The Yale Art Gallery (Chapel & York Street; 432-2600) includes extensive
collections of 17th, 18th and 19th century paintings and furnishings.
c. The British Art Center (Chapel & High Street; 432-2858) contains a collection
of British paintings, drawings, prints, rare books and sculpture assembled over
the past 35 years by Paul Mellon.
NEUROSCIENCE TRACK FACULTY RESEARCH INTERESTS
Meenakshi Alreja, In vitro electrophysiological studies on the neurobiology of the
septohippocampal pathway, a brain pathway that is involved in cognitive functions and
degenerates in Alzheimer’s disease and other neurodegenerative disorders
Amy Arnsten, Examination of the catecholamine and second messenger mechanisms
influencing the cognitive functioning of the prefrontal and entorhinal cortices, brain
regions commonly dysfunctional in mental illness
Thomas Biederer, Molecular analysis of synapse formation in the developing central
nervous system of vertebrates.
Hal Blumenfeld, Neuroimaging and electrophysiology studies of corticothalamic
mechanisms causing impaired consciousness in epilepsy.
Angelique Bordey, Glial influence on postnatal neurogenesis in the subventricular zone
Charles Bruce, Neurophysiology of information processing in cerebral cortex.
Benjamin Bunney, Neurobiology of schizophrenia and movement disorders, especially
as related to central dopaminergic systems.
John Carlson, Function and development of the Drosophila olfactory system.
Wei Chen, Functional organization of olfactory neuronal circuits.
Marvin Chun, Functional MRI studies of visual perception, memory, and executive
Lawrence Cohen, Imaging the input and output of the olfactory bulb
R. Todd Constable, Technical aspects of functional MRI with particular emphasis in
fMRI for neurosurgical planning, and the application of fMRI and ERP to better
understand language and memory systems in the human brain and the response to
Pietro De Camilli, Membrane traffic at the neuronal synapse; phosphoinositide
metabolism and neuronal function.
Sabrina Diano, Role of thyroid hormones, steroid hormones, neuropeptides and UCPs
in the homeostatic mechanisms of CNS in physio-pathological conditions.
Ronald Duman, Molecular, cellular, and anatomical sites which mediate the adaptive
responses of mammalian neurotransmitter signal transduction pathways to psychotropic
drugs, hormones, and environmental stimuli.
Barbara Ehrlich, Regulation of intracellular calcium signaling using electrophysiological,
biochemical and molecular techniques.
Paul Forscher, Molecular mechanisms of neuronal growth and guidance.
Karyn Frick, Neurobiology of learning and memory.
Jeremy Gray, fMRI studies of human emotion-cognition interactions.
Charles Greer, Mechanisms that influence axonal and dendritic growth and specificity of
targeting in sensory systems.
Lise Heginbotham, Structure-function studies of ion channel proteins.
Tamas Horvath, Determine the signaling flow and regulatory relationship within and
between neuronal circuits that underlie the maintenance of physiological and
pathological homeostatic conditions.
James Howe, Glutamate receptors.
Marcia Johnson, Cognitive neuroscience studies of human cognition and memory and
of the relation between emotion and cognition.
Sven-Eric Jordt, Molecular neurobiology of sensory transduction and pain.
Len Kaczmarek, Long-lasting changes in neuronal activity.
Haig Keshishian, Factors governing the formation of synaptic connections during
Ken Kidd, Molecular and genetic mapping of genes of neuropsychiatric relevance;
searching for genetic causes of neuropsychiatric diseases.
Jeffery Kocsis, Pathophysiology of axons and neurons.
Michael Koelle, Mechanism of signaling by G protein-coupled neurotransmitter
receptors using a combination of C. elegans genetics and biochemical experiments.
Anthony Koleske, Regulation of neuronal differentiation and morphogenesis by
nonreceptor tyrosine kinases.
Hür Köser, Creation of miniature microfluidic chambers to study cellular chemotaxis in
Robert LaMotte, Neurobiology of pain and tactile sensations.
Mark Laubach, Neurophysiological studies of associative learning, sensorimotor
integration, and the effects of aging using chronic neuronal ensemble recording in
frontal cortex, basal ganglia, and other brain areas in rodents.
David LaVan, Micro- and nano-fabrication. Development of polymer based electrodes.
Development of novel materials for biomedical applications.
Erin Lavik, Developing new therapeutic approaches for the treatment of spinal cord
injury and retinal degeneration.
Daeyeol Lee, Neural basis of decision making and sequence learning.
Michael Levene, Nonlinear optical techniques and micro-optics for in vivo microscopy;
single molecule spectroscopy.
James Mazer, Neurophysiological basis of natural vision.
Gregory McCarthy, Functional anatomy of the human brain.
David McCormick, Cellular basis for cortical and thalamic function.
Gero Miesenböck, Neuronal circuits and behavior.
Mark Mooseker, Molecular and functional analysis of the cytoskeleton, with current
emphasis on myosin superfamily of actin-based molecular motors.
Angus Nairn, Dopaminergic signal transduction in the central nervous system.
Dhasakumar Navaratnam, Molecular aspects of inner ear function.
Michael Nitabach, Behavioral and physiological genetics in the fly, with goal of
dissecting neural circuit function.
Marina Picciotto, Use of mouse genetics and molecular biological approaches to study
the role of neuromodulatory systems in behavior.
Vincent Pieribone, Information encoding in somatosensory cortex and optical probes of
Maria Mercedes Piñango, Language-brain relations: cortical dissociations in language
localization, time-course of language processing during real-time sentence
Pasko Rakic, Developmental neurobiology, genetic and epigenetic regulation of neural
George Richerson, Sensitivity to changes in pH of CNS respiratory neurons;
Electrophysiological effects of nonvesicular GABA release.
Robert Roth, Biochemistry, pharmacology, and function of midbrain dopamine systems.
Gary Rudnick, Structure and function of biogenic amine transporters, which are targets
for antidepressants and psychostimulants.
W. Mark Saltzman, Biomaterials for drug delivery in the central nervous system,
particularly in the development of controlled release systems for treating brain tumors.
Laurie Santos, Social and physical cognition in non-human primates.
Joseph Santos-Sacchi, Auditory biophysics, hair cell physiology, role of outer hair cells
in cochlear amplification.
Glenn Schafe, Neural organization of the brain’s fear system; emotional learning &
Michael Schwartz, Development and organization of connectivity in the mammalian
Nenad Sestan, Molecular control of neuronal identity and connectivity in the cerebral
Gordon Shepherd, Experimental and computational studies of sensory transduction,
synapses, dendrites, and microcircuits using the olfactory pathway as a model system.
Fred Sigworth, Ion channel structure and gating mechanisms.
Dana Small, Affective sensory neuroscience with an emphasis in multisensory
integration of taste and smell and in brain representation of feeding and food reward in
health and in addiction. Behavioral and neuroimaging approaches are used in humans.
Matthew State, Gene discovery and characterization in childhood neuropsychiatric and
Elke Stein, Axon guidance in the developing nervous system.
Stephen Strittmatter, Molecular determinants of axonal guidance during development
Jane Taylor, Neurobiology of addiction, depression and other neuropsychiatric disorders
involving motivation, learning and cognition. Behavior and molecular approaches in
mice, rats and monkeys.
Ning Tian, The development of synaptic pathways and the activity-dependent synaptic
plasticity in mammalian retina.
Susumu Tomita, Revealing molecular mechanisms for synaptic strength regulation
Vinzenz Unger, Structure and function of metal transporters; Structure of scaffolding
complexes in the postsynaptic density; Structure of membrane associated proteins.
Flora Vaccarino, Regulation of progenitor cell differentiation in normal development and
Xiao-Jing Wang, Dynamical aspects of neural computation and memory in cortex.
Stephen Waxman, Molecular neurobiology of disease, with emphasis on ion channel
function and dysfunction in spinal cord injury, multiple sclerosis, and stroke.
David Wells, Molecular mechanisms of synaptic plasticity; role of local protein synthesis.
Robert Wyman, Molecular biology and neurophysiology of gap junctions; genetic control
of neural circuit development.
Tian Xu, Mechanisms underlying neurodegeneration in Drosophila model.
Mark Yeckel, Cellular and systems characterization of cortical neurons involved in
learning and memory.
David Zenisek, Presynaptic mechanisms of retinal neurons.
Weimin Zhong, Asymmetric cell division and the development of the mammalian
Yufeng Zhou, Structure and function of ion channels.
Steven Zucker, Computational neuroscience.
Affiliated faculty – these faculty do not have an appointment in a Basic Science
Patrick Allen, Molecular mechanisms of synaptic communication
Robert Beech, Roles of transcription factors and adult neurogenesis in the neurobiology
of psychiatric disorders.
Hilary Blumberg, Understanding the neural systems that underlie emotional processing.
Nicholas T. Carnevale, Development of a theoretical framework for understanding the
functional consequences of the mechanisms that underlie the origin, propagation, and
interaction of electrical and chemical signals in neurons.
Ralph DiLeone, Understanding the molecular and neuronal circuits that are responsible
for controlling reward-related behavior.
Albert Lo, Pathobiology of demyelinating disease, neuronal injury and repair,
neuroprotection, MS epidemiology, robotic neurorehabilitation, clinical trial design and
Laura Manuelidis, Experimental models of Creutzfeldt Jakob Disease and variants;
mechanisms of dementia & infectious agents.
Rory McCrimmon, Glucose-sensing mechanisms used by specific brain regions;
metabolic adaptations in brain following recurrent exposure to low glucose.
Sam Sathyanesan, Regulation of angiogenesis in adult rodent brain and contribution to
cellular and behavioral effects.
Robert Sherwin, How the brain senses changes in blood glucose and the effect of
decrements in blood glucose on brain function.
James Swain, Combining psychological assessments and functional magnetic
resonance brain imaging to study thoughts and behaviors of parents in the early
Michael Westerveld, Memory disorders associated with epilepsy and development of
cognitive function across the lifespan.
Anne Williamson, Physiological changes seen in the chronically epileptic brain.
NEUROSCIENCE TRACK COMMITTEES
Charles Greer (Chair)
Interdepartmental Neuroscience Program Committees
Charles Greer Co-Director
Haig Keshishian Co-Director
Amy Arnsten Neurobiology
Barbara Ehrlich Pharmacology
Marvin Chun Psychology
Lawrence B. Cohen C & M Physiology
Tony Koleske Molecular Biophysics and Biochemistry
Marina Picciotto Psychiatry
Mark Yeckel Neurobiology
Jeffery Kocsis Neurology
Christian von Hehn Student Representative
Graduate Student Affairs Committee
Charles Greer (Chair)
(Student Representative to be announced)
Graduate students: Nicole Horst,
The composition of these committees is subject to rotation or change on an annual
Neuroscience Courses 2006-2007
*NSCI 501a, Principles of Neuroscience. Marina Picciotto, Mark Yeckel.
WF 3.15–4.45, TAC N203, first class meets Wednesday September 6.
General neuroscience seminar: Lectures, readings and discussion of selected topics in
neuroscience. Emphasis will be on how approaches at the molecular, cellular, physiological
and organismal levels can lead to understanding of neuronal and brain function. Also NBIO
NSCI 519a/b, Tutorial
By arrangement with faculty and approval of DGS.
NSCI 585a, Stem and Progenitor Cells in the Adult Nervous System. Eleni Markakis,
T TH 1:30 – 3:00 Hope 211
This seminar course will examine through original papers in the literature, our current
knowledge of adult neurogenesis and neural stem/progenitor cells. We will study the
advantages and disadvantages of transplantation techniques vs. recruitment of endogenous
progenitors for repair of the damaged nervous system, in a variety of animal models. The focus
will be on consensus work, but we will also delve into the controversies of neural stem cell
research. The strengths and limitations of various techniques will be examined. The semester
will end with a survey of progenitor cells used in clinical trials.
*NSCI 720a, Neurobiology. Haig Keshishian, Paul Forscher.
MWF 11:30 – 12:20 102 KBT
Examination of the excitability of the nerve cell membrane provides a starting point for the study
of molecular, cellular and intracellular mechanisms underlying the generation and control of
behavior. Also MCDB 720au, NBIO 720a.
The following course is also of particular value to students in Neuroscience:
MCDB 721Lau, Laboratory for Neurobiology. Haig Keshishian, Robert Wyman.
*NSCI 580b, Bioethics in Neuroscience. Charles Greer.
This course is an introduction to ethics and ethical decision-making in the Neurosciences.
Format for the course is an informal discussion. Each week, we will be joined by members of
the Yale faculty and community who can share their experiences and expertise as it relates to
the topic of the week. This course is mandatory for first year graduate students in the
Interdepartmental Neuroscience Program (INP). Grading is pass/fail and is determined based
on attendance/participation, weekly reaction papers and a final term paper.
NSCI 535b History of Modern Neuroscience. Gordon Shepherd.
First class meets Monday, January 22
In this course we focus on the original breakthroughs that led to major lines of research being
pursued today. Subjects include classic papers in the discoveries of DNA, action potential,
synaptic transmission, growth factors, second messengers, neurotransmitters, Hebb synapse,
dendrites, hippocampus and memory, cortical columns, REM sleep, neuroendocrine system,
instrumental conditioning, reticular activating system, psychoactive drugs, computer modeling,
and artificial intelligence. Also NBIO 535b.
NSCI 504b/MCDB 735b, Seminar in Brain Development & Plasticity. Elke Stein, Weimin
Weekly seminars (Monday) and discussion sessions (Wednesday) to explore recent advances
in our understanding of brain development and plasticity, including neuronal determination, axon
guidance, synaptogenesis and developmental plasticity. Also MCDB 735bu.
*NSCI 510b, Structural and Functional Organization of the Human Nervous System.
Michael Schwartz, Pasko Rakic.
An integrative overview of the structure and function of the human brain pertaining to
major neurological and psychiatric disorders. Also NBIO 500b.
NSCI 514b, Neurodevelopment and Neuropsychiatric Disorders. Flora Vaccarino.
This course is intended to discuss the development of the central nervous system as it applies
to neuropsychiatric disorders. We will focus on the mechanisms that regulate progenitor cell
proliferation, the acquisition of regional and cellular identity, neuronal migration and cell death.
Information drawn from these basic developmental mechanisms will be used to discuss the
newest emerging ideas about the pathogenesis of disorders such as autism, Tourette’s
syndrome, depression and other affective disorders.
NSCI 502b, Cell Biology of the Neuron, Elke Stein
MW 4:30 – 6 pm