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Alirocumab effect on new-onset or worsening diabetes, blood glucose, and HbA1c.

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Alirocumab effect on new-onset or worsening diabetes, blood glucose, and HbA1c.

  1. 1. Data abstractedfrom ACC15 AbstractA1363, PooledSafetyandAdverseEventsinNine Randomized, Placebo-Controlled,Phase 2andPhase 3 Clinical Trialsof Alirocumab. J Am Coll Cardiol. 2015; 65(10_S). doi: 10.1016/S0735-1097(15)61363-8. Alirocumab Placebo N=2482 N=1277 Adverse events,%(n) Anytreatment-emergent diabetesorworseningof preexistingdiabetes 3.4 (83) 3.1 (40) Otherclinical laboratorydata. Week52 change frombaseline. N=2318 N=1174 Fastingglucose,mmol/L,mean (SD) 0.16 (1.52) 0.13 (1.64) HemoglobinA1c%,mean(SD) 0.10 (0.66) 0.07 (0.54)

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