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New Technologies in Caries Diagnosis: The Canary System in Pediatric Practice

Shifting from a surgical approach in Dentistry to one of risk management and meaningful prevention because we know that when a lesion is left to extend until a filling is needed, the clinical opportunity for effective prevention is lost.

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New Technologies in Caries Diagnosis: The Canary System in Pediatric Practice

  1. 1. NEW TECHNOLOGIES INCARIES DIAGNOSISThe Canary System inPediatric PracticeDr. Ian McConnachieAAPD Annual Session May 24-27, 2012
  2. 2. A couple of Gifts from the North
  3. 3. Disclosures • No Commercial Interest or Reimbursement from Quantum Dental Technologies • Member of Unpaid Dentist Advisory Panel to Quantum Dental Technologies • Some slides provided by QDT
  4. 4. Acknowledgements Page 4 • DR. STEPHEN ABRAMS President and CEO of Quantum Dental Technologies • DR. MARIELLE PARISEAU Creator of Note: The current final version of this presentation will be available on the Shaping the Future of Dentistry website later this week. Look in Menu under Resources
  5. 5. New Technologies in Caries Diagnosis • Diagnodent by KaVo • Caries ID by Dentsply • Spectra by Air Techniques • CarieScan by CarieScan Ltd • The Canary System by Quantum Dental Technologies
  6. 6. Outline of the presentation A Micro Review of Cariology Measuring and Recording Decay - The Current Reality The Shift in Dealing with Decay Newer Technologies Detecting Decay The Canary System Use of the Canary in Pediatric Dentistry – The 9 Month Story Canary-Ready for Prime Time?
  7. 7. Early Carious Lesion in Enamel
  8. 8. Pathogenesis of Dental Caries (biological balances) SALIVA PLAQUE PLAQUE ENAMEL ENAMEL Polysaccharides Calcium Salts Plaque buffers mouth inside of tooth SUGARS ACID Calcium Salts Bacterial Enzymes Salivary buffersDemineralization Re-mineralization
  9. 9. Measuring and recording decay THE CURRENT REALITY • Visual Exam • Mirror and Explorer • Dental Radiographs • Transillumination • Dmfs/dmft
  10. 10. Methods for Caries Detection Conventional methods • Visual examination: + non-destructive + safe - poor resolution - unable to detect incipient demineralization - unable to detect subsurface caries • X-rays: + non-destructive + can detect subsurface caries - limited safety - unable to detect incipient demineralization - low resolution
  11. 11. Radiographs • Radiographic imaging of pits and fissures is of minimal diagnostic value because of the large amounts of surrounding enamel . • Literature review by Dove: • “overall the strength of the evidence for radiographic methods for the detection of dental caries is poor for all types of lesions on proximal and occlusal surfaces”. • “it is beneficial only if the intervention is the surgical removal of tooth structure and detrimental if it is used for non-invasive remineralization methods.” McKnight-Hanes C, Myers DR, Dushku JC, Thompson WO, Durham LC. Radiographic recommendations for the primary dentition: comparison of general dentists and pediatric dentists. Pediatr Dent. 1990 Jul-Aug;12(4):212-216 Flaitz CM, Hicks MJ, Silverston LM. Radiographic, histologic, and electronic comparison of basic mode videoprints with bitewing radiography. Caries Res. 1993; 27(1): 65-70. Lussi A, Comparison of different methods for the diagnosis of fissure caries without cavitation. Caries Res 27:409-16, 1993 Dove,  S.  B.,  “Radiographic  Diagnosis  of  Dental  Caries  in  Consensus  Conference  on   Dental Caries Management Throughout Life, March 2001, Journal of Dental Education, 2001; 65 (10): 985 – 990
  12. 12. NO BIG DEAL
  13. 13. A VERY BIG DEAL Psychological impact Lower body weight
  14. 14. A TRANSMISSIBLE BACTERIAL INFECTION Caries is a transmissible bacterial infection and a multifactorial disease that reflects change in one or more significant factors in the total oral environment. (NIH Consensus Conference 2001) Diagnosis involves recognition of these changes rather than simply noting cavities
  16. 16. BECAUSE FILLINGS Don’t treat underlying disease Don’t address plaque biofilm issues Don’t change risk level We need to from a surgical approach to a RISK management & preventive approach.
  17. 17. The SHIFT in Dealing with Decay • Growing awareness of social determinants • Newer recording of caries levels- ICDAS • Risk-based care • A myriad of new products • New diagnostic devices
  18. 18. “ It is change, continuingchange, inevitable change,that is the dominant factor insociety today. No sensibledecision can be made anylonger without taking intoaccount not only the worldas it is, but the world as itwill be” Isaac Asimov
  19. 19. Product Decisions? Fluoride • RISK Demand? CPP-ACP (Recaldent) • Age and Ability? NovaMin • Buffering? ProArgin • Fluoride Uptake? Xylitol products Antibacterial rinses • Contact time needed? Salivary products • Desensitization? Neutralizing agents • Antibacterial Activity? Silver Diamine Fluoride • Salivary Stimulant? Povidone Iodine • Compliance? CHX varnish (Prevora) Sealants ICON
  20. 20. Newer TechnologiesDetectingDecay
  21. 21. The Value of Early Detection 1. Is the ability to control the disease process in order 1. To contain, arrest or remineralize lesions, in order 2. To avoid or delay the burdens or costs associated with a spiral of restoration and re- restoration If a lesion is left to extend until a filling is needed, the clinical opportunity for effective prevention is lost
  22. 22. New Technology Methods For Caries Detection Fluorescence-based Technology • Diagnodent • Caries ID • Quantitative Light-Induced Fluorescence • Spectra (QLF Technology) Digital Fibreoptic Transillumination (DIFOTI) Electrical Impedance Measurement • Caries Scan
  23. 23. The Characteristics of an Ideal Caries Detection System Primary • High sensitivity & specificity for caries detection • Detects & monitors de & re-mineralization • Detects smooth surface, root surface, occlusal surface & interproximal lesions • Detects caries around restoration margins • Non-invasive & safe • Repeatable measurements
  24. 24. The Characteristics of an Ideal Caries Detection System Secondary • Imaging and or image capture • System for recording & storing measurements • Patient Education and Motivation • In-vitro and in-vivo data & publications • Minimal or no preparation of the tooth surface prior to taking a reading • Ability to detect and monitor erosion lesions
  25. 25. The Characteristics of an Ideal Caries Detection System The key is to understand what the device is measuring
  26. 26. Sensitivity and Specificity Sensitivity • The proportion of true positives correctly identified by the test Specificity • The proportion of true negatives correctly identified by the test Therefore, an experimental test aims to achieve 100% sensitivity (no false positives) and 100% specificity (no false negatives) Because these are proportions, can calculate confidence intervals Closer the C.I. is to 1.0 the better
  27. 27. The Canary System
  28. 28. by Quantum Dental Technologies Canary interactive software and printed patient reports The Canary Console
  29. 29. Science Behind The Canary System•Pulses of laser light hit the tooth surface.•Tooth glows (Luminescence, LUM) and releases heat (Photo- Thermal Radiometry, PTR).•PTR can provide a depth profile by varying the frequency of the laser beam. Temperature increase < 1oC not harmful•Detected  signals  reflect  the  tooth’s  condition.  •Detects 50 micron lesion up to 5 mm below the surface.
  30. 30. What it is - Screenshot Odontogram MenuOptions Camera Image Canary Number
  31. 31. Caries Mapping Camera Image with Grid Canary Number
  32. 32. Canary Patient Report • Customized patient report on dental practice letterhead • Clear simple indication of problem areas • Patient can track their progress • Engages patient in their oral health care
  33. 33. Internet Connectivity • The Canary System equipped with wireless connect to the  ‘Canary  Cloud’. • Benefits for internet connectivity include: – Back-up and storage of data – Seamless software updates – Data and risk analysis for report generation – Online access of patient reports via Canary Web Portal – Access to data even when the system is being serviced or upgraded – Enables dentists to access all patient data among all dental operatories – HIPPA and PIPEDA Compliant
  34. 34. VALUE PROPOSITION Value to the Dentist • Attract new patients: with state of the art technology and a minimally invasive approach • More patient visits: more frequent visits for patients enrolled in remineralization programs • Reduce costs: scans can be performed by lower cost staff (hygienists, assistants) • Affordable: flexible leasing options provide immediate profitability Value to Patients & Insurers • Reduce costly & painful restorations
  35. 35. The Life Cycle of Tooth Decay Healthy Early Advanced Tooth Enamel Decay Enamel Decay Demineralization Remineralization Remineralization Therapies The Canary System Scan X-Ray, Drill Fill & Bill
  36. 36. Caries Detection on ALL Surfaces• Between teeth(interproximal areas) • Around the edges of fillings • Enamel and root surfaces Canary detects small lesions • Biting Surfaces from 50 microns in depth and (occlusal pits and fissures) up to 5 mm below the tooth surface.
  37. 37. Sensitivity and Specificity Sensitivity • Overall measurement in vitro 97% Specificity • Overall measurement in vitro 82% *Bench study Dr. B Amaechi UTSA
  38. 38. Integrating into Dental Practice• Scanning done by lower cost staff (dental assistant)• Applying remineralizing therapies• Return for repeat monitoring of suspect lesions• Good practice management tool
  39. 39. The Canary in Pediatric Practice – THE 9 MONTH STORY Our questions at the start • How easy to measure • How reproducible • How accurate • Canary Scale 21-70 • Specificity and Sensitivity
  40. 40. The Canary in Pediatric Practice – THE 9 MONTH STORY Lesions evaluated clinically Pit and fissure Interproximal Facial Under sealants ICON Under and around restorations
  41. 41. Pit and Fissure Caries
  42. 42. Pit and Fissure Caries
  43. 43. Pit and Fissure Caries
  44. 44. Pit and Fissure Caries
  45. 45. Interproximal lesions Issues at Outset • How easy to learn • How reproducible the numbers • Canary Scale 21-70 • Sensitivity and specificity
  46. 46. Houston, We Had a Problem
  47. 47. Range of Measurements Verified by Treatment Surface ICDAS # Canary # Permanent Occlusal 2 13-19 3 17-34 4 24-53 Interproximal (Pre-Adjustment) 2 24-26 4 21-29 (Post Adjustment) 3,4 32-40 (small sample size)
  48. 48. Interproximal lesions The key is to understand what the device is measuring • Canary number will under report lesion size • Intervention decisions remain based on CAMBRA
  49. 49. Detecting Caries under a Sealant
  50. 50. Detecting Caries under a Sealant
  51. 51. Detecting Caries under a Sealant Lab study on extracted teeth comparing Canary and Diagnodent Sensitivity • Canary 0.83 • Diagnodent 0.64 Specificity • Canary 0.79 • Diagnodent 0.46 • ORCA Abstract from QDT 2012
  52. 52. Detection Around ICON Issues With ICON • Newer technology with limited in-vivo data • Caries development around and within material unknown • Longevity of material unknown • Potentially a very useful material • How to monitor for early change
  53. 53. Detection Around ICON
  54. 54. Detection Around ICON
  55. 55. Anomalous Lesion
  56. 56. Anomalous Lesion Characteristics • No surface breakdown (ICDAS 1 or 2) • Evident radiographically, often for a year or longer • Once  through  enamel  you  “drop”  into  defect • Lesion tends to be reddish-brown  and  “mushy” • Does not exhibit typical carious texture • Suspicion is the histological picture is distinct from traditional caries picture
  57. 57. Anomalous Lesion
  58. 58. Anomalous Lesion – Preliminary Page 76Observations • Canary does not accurately measure defect • Lesion appears to have a different pathology and suspected different histological picture • More information required
  59. 59. Preliminary Observations on CanaryOverall Occlusal Surface • Highest ease of measurement and predictability Facial surface • Highest ease of measurement and predictability Interproximal Permanent Teeth • Significant learning curve • Lesion will be at least as deep as measurement indicates
  60. 60. Preliminary Observations on Canary(cont’d) Interproximal Primary Teeth • Greater accuracy of Canary number compared to permanent teeth Under Sealants • Very good indicator of what lies beneath ICON • Likely good indicator of change with repeat scans Under and Around Restorations • Good indicator of restoration failure
  61. 61. Orthodontic Treatment – A Unique Opportunity Facts on Orthodontic-Related Decalcification and Caries • Approximately 50% of ortho cases  end  with  “white   spot  lesions” • Lesions can commence within 1 month of bracketing • Braces can preclude bitewing radiographs for 3 years or longer • Risk-based preventive strategies exist • Canary System an excellent diagnostic tool
  62. 62. Orthodontic decalcifications and caries Slide courtesy of Reliance Orthodontics
  63. 63. Orthodontic Treatment – RecommendedCanary Protocol • Collaboration and communication triad established pre-orthodontics • Baseline risk assessment • Baseline bitewing radiographs • If moderate or high risk then full Canary scan at baseline • Rescan of interproximal and facial surfaces at 3-6 months based on risk • Customized preventive strategy for home, primary care office and orthodontic office
  64. 64. Dear Dr. Re: PatientOur mutual patient was in recently for regular care. You will recall that he/she demonstrates ahigher risk for dental caries. As a result, we have initiated a customized preventive programmefor him/her while undergoing the orthodontic care under your supervision. Specific componentsof this preventive programme include:___ Higher fluoride toothpaste used at bedtime___ More frequent dental hygiene visits for scaling, prophylaxis___ More frequent dental hygiene visits for additional fluoride varnish application___ Review of home hygiene techniques including use of floss and proxybrush___ Scanning of at risk sites on teeth with the Canary SystemThe  current  review  of  ________’s  oral  hygiene  and  caries  status  reveals:___ Oral hygiene is under control___ Adjustments to the preventive programme are required and involve the following:___ A rescan of the at risk sites is planned for ___ monthsWe appreciate your collaboration in the oral care for _______. Please contact our office if youhave concerns about anything for him/her.Sincerely yours,
  65. 65. The Canary: Clinical Indications • Complementary to bitewing radiographs – may reduce frequency need • Monitor of remineralization therapy • Monitor of margins of existing restorations • Monitor of pre-cavitated lesions on all surfaces • Complement to Caries Management by Risk Assessment • Part of collaboration triad in orthodontic care
  66. 66. Office Integration Recall or Specific Exam Reassess 6 Months •Identify White Spots •Assess Lesion •ICDAS or Measure •ICDAS or Measure •Risk Assessment •Apply Remineralization •Apply Therapy Remineralization •Oral Hygiene Therapy Instruction •Dispense Home- •Provide Home-based Based Therapy Therapy Reassess 3 Months •Assess lesion •ICDAS or Measure •Apply Remineralization therapy •Dispense Home- based therapy
  67. 67. The Characteristics of an Ideal Caries DetectionSystem - How Does Canary Rate? Primary ? - High sensitivity & specificity for caries detection YES - Detects & monitors de & re-mineralization YES BUT- Detects smooth surface, root surface, occlusal surface & interproximal lesions YES - Detects caries around restoration margins YES - Non-invasive & safe YES BUT - Repeatable measurements The key is to understand what the device is measuring.
  68. 68. The Characteristics of an Ideal Caries Detection System Secondary YES - Imaging and or image capture YES - System for recording & storing measurements YES - Patient Education and Motivation YES but More Needed - In-vitro and in-vivo data & publications YES BUT - Minimal or no preparation of the tooth surface prior to taking a reading ? - Ability to detect and monitor erosion lesions The key is to understand what the device is measuring.
  69. 69. Is This the Motherlode In Caries Diagnosis? MAYBE – BUT DEFINITELY WORTH CONSIDERING