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Malaria vaccine trialsA journey through the process
Before a vaccineclinical trial begins,community meetingsare held.
Next, potential participantshave in-person screeningsand interviews.
Once screenings are complete, physical exams areadministered.                                              4
If children’s parents choose to continue with enrollment in thevaccine trial, trial staff take them through the consenting...
Consented participantsare then able to receivethe trial or control vaccine.
Participants return for check upsthroughout the trial period.
If a participant becomesill due to any cause,she or he is treated.And, thanks to clinicaltrials, participants canbe diagno...
The broader communityalso benefits from accessto such equipment andenhanced facilities.Radiology equipment, forexample, ma...
Training opportunities for medical staff also end up benefiting thecommunities in which trials take place, by helping to a...
Clinical trials would not be possible, however, were                             it not for the community members who volu...
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Malaria vaccine trials: a journey through the process

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Enrollment of participants in a vaccine trial in Africa requires a complex process. The process typically involves community meetings, in-person screenings and interviews, physical exams, and a formal consenting process to ensure that the volunteer or responsible caregiver understands both the trial procedures and the potential risks and benefits.

In the case of a “blinded” trial, neither the participants nor those administering the vaccine know who is receiving the candidate vaccine being tested or who is receiving the control vaccine. Using images from malaria vaccine trial sites in Africa, the presentation above offers a view of the process and also illustrates the improvements in health care technology that may follow from the participation of research centers in such trials.

Published in: Health & Medicine, Business
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Malaria vaccine trials: a journey through the process

  1. 1. Malaria vaccine trialsA journey through the process
  2. 2. Before a vaccineclinical trial begins,community meetingsare held.
  3. 3. Next, potential participantshave in-person screeningsand interviews.
  4. 4. Once screenings are complete, physical exams areadministered. 4
  5. 5. If children’s parents choose to continue with enrollment in thevaccine trial, trial staff take them through the consenting process.
  6. 6. Consented participantsare then able to receivethe trial or control vaccine.
  7. 7. Participants return for check upsthroughout the trial period.
  8. 8. If a participant becomesill due to any cause,she or he is treated.And, thanks to clinicaltrials, participants canbe diagnosed usingmodern medicalequipment, such as thisdigital radiologymachine.
  9. 9. The broader communityalso benefits from accessto such equipment andenhanced facilities.Radiology equipment, forexample, may be locatedin a hospital and thus isaccessible to others whofall ill.
  10. 10. Training opportunities for medical staff also end up benefiting thecommunities in which trials take place, by helping to attract high-quality staff who in turn provide higher quality healthcare services.
  11. 11. Clinical trials would not be possible, however, were it not for the community members who volunteer themselves or their loved ones to participate.Photos: David Poland and Sally Ethelston, PATH

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