Class 2CNS Stimulants<br />
Ch. 20-Benzodiazepines/Anxiolytics<br />Oxazepam<br />triazolam<br />
Barbiturates<br />Greater Sedation<br />Great Dependence<br />
Chapter 20: AnxiolyticsHypnotics<br />
SE of Hypnotics, Anxiolytics, Sleep AidsSedation <br />
Drowsiness<br />
Lethargy<br />
Blurred Vision<br />
Confusion<br />
Dry Mouth<br />
Constipation<br />
Nausea/Vomiting<br />
Hypotension<br />
Urinary Retention<br />
Antidepressants: Signs of Depression<br />
Sleep disturbances<br />
Lack of appetite<br />
Limited Libido<br />
Feelings of Sadness<br />
Inability to perform daily activities<br />
Tricyclic Antidepressants-TCAs<br />
Prototype: Imipramine<br />
Monoamine Oxidase inhibitors<br />
MAOI Interactions<br />
Selective Serotonin Reuptake Inhibitors<br />
Serotonin Syndrome<br />
Other Antidepressants<br />
Ch. 22: Psychotherapeutic DrugsAntipsychotics/Neuroleptics: Used to Treat<br />Schizophrenia<br />Narcolepsy/ADD<br />Mani...
Typical Antipsychotics<br />
Atypical Antipsychotics<br />
Antipsychotics & Adolescents<br />
Antipsychotics and Dementia<br />
Antipsychotic SE<br />Akathisia<br />Tongue thrusting<br />Facial grimacing<br />Jerking of head<br />Mouth puckering<br /...
Anti-Mania Drugs<br />Lithium<br />Therapeutic Level:<br />0.6-1.2 mEq/L<br />
CNS Stimulants<br />
Anti-Seizure Drugs<br />Hydantoins<br />
Confusing Drug Names??<br />Celebrex<br />Cerebyx<br />Celexa<br />
Dilantin-Phenytoin<br />Serious Skin Reactions: Side/Adverse Effects<br />Gingival hyperplasia<br />Liver toxicity<br />CN...
Other  Drugs for Seizures:Benzodiazepams: Klonopin & Valium<br />
Central Nervous System<br />
Use of CNS Stimulants<br />ADHD<br />Narcolepsy<br />Cluster Headaches/Migraines<br />
Anorexiants: Obesity<br />NO MORE Phenylpropanolamine<br />
Xanthines<br />Purpose: stimulate respiration in newborns<br />Side effects: restlessness, tremors, twitching, palpitation...
Caffeine<br />Increased alertness; Diuretic, cardiovascular stimulation, bronchodilation, increased GI secretion, skeletal...
Item<br />Item Size<br />Caffeine Content (mg)<br />Coffee<br />150 ml (5 oz)<br />60-150<br />               <br />      ...
Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />Coca Cola<br />12 oz<br />45<br />Tab<br />12 oz<br />46...
Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />This is No BULL!<br />Red Bull contains approx 80 mg caf...
And What about Starbucks? (amounts vary by web site)<br />Coffee, tall (12 oz.) 240 mg<br />Coffee, venti (20 oz.) 480 mg<...
Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />OTC Drugs with Caffeine<br />Dextrim<br />200<br />     ...
Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />Caffeine in Common Products<br />Caffeine IS addictive<b...
Respiratory CNS Stimulant<br />Purposes: respiratory depression from drug overdose, postanesthetic respiratory depression,...
Herbal Stimulants<br />Guarana<br />High in caffeine<br />Found in weight loss products and energy drinks<br />Ma Huang<br />
Peripheral Nervous System<br />
Autonomic Nervous System<br />
Sympathetic Nervous System:Fight or Flight<br />
STRESS!!!!<br />
Parasympathetic Nervous System: controls Pee, Poop, Puke <br />
Adrenergic Drugs <br />
Alpha Adrenergic Blocking Agents<br />
Alpha Adrenergic Blocking Agents<br />Examples of alpha blockers include: <br />Alfuzosin (Uroxatral)<br />Doxazosin (Card...
Alpha Adrenergic Blocking Agents<br />
Alpha Adrenergic Blocking Agents<br />
Beta Adrenergic Blocking Agents<br />
Beta Adrenergic Blocking Agents<br />Assess BP, Heart Rate<br />
Effects of Beta Blockers:<br />Pupil construction<br />Tears<br />Saliva<br />Slow Heart Rate<br />Bronchoconstriction<br ...
Cholinergic Drugs<br />
Myasthenia Gravis<br />Tensilon Test (edrophonium)<br />
Cholinergics<br />Organophosphates used as incecticides<br />Sarin Gas-Bioterrorism<br />Antidote<br />
Drugs for Alzheimer’s Disease<br />Cholinesterase Inhibitors:<br />Razadyne® (galantamine)<br />	Exelon® (rivastigmine)<br...
Cholinergic Blocking AgentsAKA Anticholinergics<br />
Anticholinergic Effects<br />RED AS A BEET<br />
Anticholinergic Effects<br />DRY AS A BONE<br />
Anticholinergic Effects<br />MAD AS A HATTER<br />
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Class 2 nsg 2500 Summer 2011

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Class 2 nsg 2500 Summer 2011

  1. 1. Class 2CNS Stimulants<br />
  2. 2. Ch. 20-Benzodiazepines/Anxiolytics<br />Oxazepam<br />triazolam<br />
  3. 3. Barbiturates<br />Greater Sedation<br />Great Dependence<br />
  4. 4. Chapter 20: AnxiolyticsHypnotics<br />
  5. 5. SE of Hypnotics, Anxiolytics, Sleep AidsSedation <br />
  6. 6. Drowsiness<br />
  7. 7.
  8. 8. Lethargy<br />
  9. 9. Blurred Vision<br />
  10. 10. Confusion<br />
  11. 11. Dry Mouth<br />
  12. 12. Constipation<br />
  13. 13. Nausea/Vomiting<br />
  14. 14. Hypotension<br />
  15. 15. Urinary Retention<br />
  16. 16. Antidepressants: Signs of Depression<br />
  17. 17. Sleep disturbances<br />
  18. 18. Lack of appetite<br />
  19. 19. Limited Libido<br />
  20. 20. Feelings of Sadness<br />
  21. 21. Inability to perform daily activities<br />
  22. 22. Tricyclic Antidepressants-TCAs<br />
  23. 23. Prototype: Imipramine<br />
  24. 24. Monoamine Oxidase inhibitors<br />
  25. 25. MAOI Interactions<br />
  26. 26. Selective Serotonin Reuptake Inhibitors<br />
  27. 27. Serotonin Syndrome<br />
  28. 28. Other Antidepressants<br />
  29. 29. Ch. 22: Psychotherapeutic DrugsAntipsychotics/Neuroleptics: Used to Treat<br />Schizophrenia<br />Narcolepsy/ADD<br />Mania/BiPolar disorder<br />
  30. 30. Typical Antipsychotics<br />
  31. 31. Atypical Antipsychotics<br />
  32. 32. Antipsychotics & Adolescents<br />
  33. 33. Antipsychotics and Dementia<br />
  34. 34. Antipsychotic SE<br />Akathisia<br />Tongue thrusting<br />Facial grimacing<br />Jerking of head<br />Mouth puckering<br />Finger movement<br />Blinking<br />Rolling the tongue around the mouth<br />Twitching hands <br />Tapping feet<br />Twisting the trunk<br />
  35. 35. Anti-Mania Drugs<br />Lithium<br />Therapeutic Level:<br />0.6-1.2 mEq/L<br />
  36. 36. CNS Stimulants<br />
  37. 37. Anti-Seizure Drugs<br />Hydantoins<br />
  38. 38. Confusing Drug Names??<br />Celebrex<br />Cerebyx<br />Celexa<br />
  39. 39. Dilantin-Phenytoin<br />Serious Skin Reactions: Side/Adverse Effects<br />Gingival hyperplasia<br />Liver toxicity<br />CNS depression<br />
  40. 40. Other Drugs for Seizures:Benzodiazepams: Klonopin & Valium<br />
  41. 41. Central Nervous System<br />
  42. 42. Use of CNS Stimulants<br />ADHD<br />Narcolepsy<br />Cluster Headaches/Migraines<br />
  43. 43. Anorexiants: Obesity<br />NO MORE Phenylpropanolamine<br />
  44. 44. Xanthines<br />Purpose: stimulate respiration in newborns<br />Side effects: restlessness, tremors, twitching, palpitations, insomnia<br />Xanthines (methylxantine)<br />Caffeine used in newborns with respiratory distress to stimulate respirations<br />Theophylline<br />
  45. 45. Caffeine<br />Increased alertness; Diuretic, cardiovascular stimulation, bronchodilation, increased GI secretion, skeletal muscle stimulation<br />Large amts can cause excessive CNS stimulation: Anxiety, agitation, diarrhea, insomnia, irritable, nervous, PVCs, <br />Toxicity: Delirium, seizures<br />Withdrawal: Headache, fatigue, muscle pain<br />
  46. 46. Item<br />Item Size<br />Caffeine Content (mg)<br />Coffee<br />150 ml (5 oz)<br />60-150<br />               <br />          <br />Coffee, decaf<br />150 ml (5 oz)<br />2-5<br />Tea<br />150 ml (5 oz)<br />40-80<br />Hot Cocoa<br />150 ml (5 oz)<br />1-8<br />Chocolate Milk<br />225 ml<br />2-7<br />Jolt Cola<br />12 oz<br />71<br />Josta<br />12 oz<br />58<br />Mountain Dew<br />12 oz<br />55<br />Surge<br />12 oz<br />51<br />Tab<br />12 oz<br />47<br />Diet Coca Cola<br />12 oz<br />45<br />Coca Cola<br />12 oz<br />45<br />
  47. 47. Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />Coca Cola<br />12 oz<br />45<br />Tab<br />12 oz<br />46<br />RC Cola<br />12 oz<br />43<br />Dr. Pepper<br />12 oz<br />41<br />Mr. Pibb<br />12 oz<br />40<br />Pepsi Cola<br />12 oz<br />37<br />Cherry Coca-Cola<br />8 oz<br />31<br />7-Up<br />12 oz<br />0<br />Mug Root Beer<br />12 oz<br />0<br />Sprite<br />12 oz<br />0<br />
  48. 48. Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />This is No BULL!<br />Red Bull contains approx 80 mg caffeine in one can (similar to a cup of regular coffee)<br />Caffeine is FATAL in doses of 10 grams<br />
  49. 49. And What about Starbucks? (amounts vary by web site)<br />Coffee, tall (12 oz.) 240 mg<br />Coffee, venti (20 oz.) 480 mg<br />Coffee, short (8 oz.) 180 mg<br />Coffee, grande (16 oz.) 320 mg<br />
  50. 50. Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />OTC Drugs with Caffeine<br />Dextrim<br />200<br />               <br />Vivarin<br />200<br />No Doz<br />100<br />Excedrin<br />65<br />Vanquish<br />33<br />Anacin<br />32<br />Midol<br />32<br />Triaminicin<br />30<br />Dristan<br />16<br />
  51. 51. Copyright 2003, Elsevier Science (USA). All Rights Reserved.<br />Caffeine in Common Products<br />Caffeine IS addictive<br />3-4 cups of coffee is maximum recommended/day<br />Listed as GRAS (Generally Recognized as Safe!)<br />Should be avoided by pregnant women, people with CAD, HTN<br />
  52. 52. Respiratory CNS Stimulant<br />Purposes: respiratory depression from drug overdose, postanesthetic respiratory depression, occasionally COPD<br />Doxapram (Dopram)<br />
  53. 53. Herbal Stimulants<br />Guarana<br />High in caffeine<br />Found in weight loss products and energy drinks<br />Ma Huang<br />
  54. 54. Peripheral Nervous System<br />
  55. 55. Autonomic Nervous System<br />
  56. 56. Sympathetic Nervous System:Fight or Flight<br />
  57. 57. STRESS!!!!<br />
  58. 58. Parasympathetic Nervous System: controls Pee, Poop, Puke <br />
  59. 59. Adrenergic Drugs <br />
  60. 60. Alpha Adrenergic Blocking Agents<br />
  61. 61. Alpha Adrenergic Blocking Agents<br />Examples of alpha blockers include: <br />Alfuzosin (Uroxatral)<br />Doxazosin (Cardura)<br />Prazosin (Minipress)<br />Terazosin (Hytrin)<br />Tamsulosin (Flomax)<br />
  62. 62. Alpha Adrenergic Blocking Agents<br />
  63. 63. Alpha Adrenergic Blocking Agents<br />
  64. 64. Beta Adrenergic Blocking Agents<br />
  65. 65. Beta Adrenergic Blocking Agents<br />Assess BP, Heart Rate<br />
  66. 66. Effects of Beta Blockers:<br />Pupil construction<br />Tears<br />Saliva<br />Slow Heart Rate<br />Bronchoconstriction<br />Increased GI motility<br />Urinary Frequency<br />
  67. 67. Cholinergic Drugs<br />
  68. 68. Myasthenia Gravis<br />Tensilon Test (edrophonium)<br />
  69. 69. Cholinergics<br />Organophosphates used as incecticides<br />Sarin Gas-Bioterrorism<br />Antidote<br />
  70. 70. Drugs for Alzheimer’s Disease<br />Cholinesterase Inhibitors:<br />Razadyne® (galantamine)<br /> Exelon® (rivastigmine)<br /> Aricept® (donepezil). <br />Nursing Care??<br />Namenda® (memantine)<br />
  71. 71. Cholinergic Blocking AgentsAKA Anticholinergics<br />
  72. 72. Anticholinergic Effects<br />RED AS A BEET<br />
  73. 73. Anticholinergic Effects<br />DRY AS A BONE<br />
  74. 74. Anticholinergic Effects<br />MAD AS A HATTER<br />

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