ENCAPSULA NANOSCIENCES LLC                            MATERIAL SAFTEY DATA SHEET                                          ...
ENCAPSULA NANOSCIENCES LLC                       MATERIAL SAFTEY DATA SHEET              OSHA HAZARDS TARGET ORGAN EFFECT:...
ENCAPSULA NANOSCIENCES LLC                       MATERIAL SAFTEY DATA SHEET       AUTOIGNITION TEMP              N/A      ...
ENCAPSULA NANOSCIENCES LLC                       MATERIAL SAFTEY DATA SHEET9. PHYSICAL AND CHEMICAL PROPERTIES       Appea...
ENCAPSULA NANOSCIENCES LLC                      MATERIAL SAFTEY DATA SHEET      Ingestion:        May be harmful if swallo...
ENCAPSULA NANOSCIENCES LLC                    MATERIAL SAFTEY DATA SHEET               Dispose of as unused product.14. TR...
ENCAPSULA NANOSCIENCES LLC                     MATERIAL SAFTEY DATA SHEET               This product does not contain any ...
Upcoming SlideShare
Loading in …5
×

MSDS for Mannosylated Clodronate Liposome (m-Clodrosome)

574 views

Published on

MDSD for mannosylated clodronate liposomes used for macrophage. monocyte and dendritic cell depletion in animal models.

Published in: Technology
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
574
On SlideShare
0
From Embeds
0
Number of Embeds
107
Actions
Shares
0
Downloads
5
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

MSDS for Mannosylated Clodronate Liposome (m-Clodrosome)

  1. 1. ENCAPSULA NANOSCIENCES LLC MATERIAL SAFTEY DATA SHEET Date Created: 02/05/20131. PRODUCT AND COMPANY IDENTIFICATION Product name: MANNOSYLATED FLUORESCENT CLODROSOME LIPOSOME Product number: m-CLOD Brand: m-CLODROSOME® Company Address: ENCAPSULA NANOSCIENCES LLC 441 DONELSON PIKE, SUITE 345 NASHVILLE, TN 37214, USA Technical Phone: 615-884-4442 Fax: 615-250-8747 Emergency Phone: 615-438-85532. COMPOSITION/INFORMATION ON INGREDIENTS Substance Name CAS# SARA313 m-CLODROSOME NONE No Ingredient Name CAS # Percent SARA313 WATER 7732-18-5 >90 No SODIUM CHLORIDE 7647-14-5 <5 No POTASSIUM CHLORIDE 7447-40-7 <5 No DISODIUM PHOSPHATE 7558-79-4 <5 No POTASSIUM PHOSPHATE 7758-11-4 <5 No L-α-PHOSPHATIDYLCHOLINE 8002-43-5 <5 No CHOLESTEROL 57-88-5 <5 No CLODRONATE DISODIUM 22560-50-5 <5 No 4-AMINOPHENYL--D-MANNOPYRANOSIDE 34213-86-0 <5 No3. HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
  2. 2. ENCAPSULA NANOSCIENCES LLC MATERIAL SAFTEY DATA SHEET OSHA HAZARDS TARGET ORGAN EFFECT: BONE, KIDNEY HMIS RATING HEALTH: 0 CHRONIC HEALTH HAZARD: * FLAMMABILITY: 0 REACTIVITY: 0 NFPA RATING HEALTH: 0 FLAMMABILITY: 0 REACTIVITY: 0 POTENTIAL HEALTH EFFECTS Inhalation May be harmful if inhaled. May cause respiratory tract irritation. Skin May be harmful if absorbed through skin. May cause skin irritation. Eyes May cause eye irritation. Ingestion: May be harmful if swallowed.4. FIRST AID MEASURES ORAL EXPOSURE If swallowed, wash out mouth with water provided person is conscious. Call a physician. INHALATION EXPOSURE If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. DERMAL EXPOSURE In case of contact, immediately wash skin with soap and copious amounts of water. EYE EXPOSURE In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.5. FIRE FIGHTING MEASURES FLASH POINT N/Am-CLODROSOME www.clodrosome.com
  3. 3. ENCAPSULA NANOSCIENCES LLC MATERIAL SAFTEY DATA SHEET AUTOIGNITION TEMP N/A FLAMMABILITY N/A EXTINGUISHING MEDIA Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. FIREFIGHTING Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Specific Hazard(s): Emits toxic fumes under fire conditions.6. ACCIDENTAL RELEASE MEASURES METHODS FOR CLEANING UP Absorb on sand or vermiculite and place in closed containers for disposal. Ventilate area and wash spill site after material pickup is complete.7. HANDLING AND STORAGE HANDALING User Exposure: Do not breathe vapor. Do not get in eyes, on skin, on clothing. STORAGE Suitable: Keep tightly closed under an inert gas. Store in refrigerator at 4 °C.8. EXPOSURE CONTROLS/ PERSONAL PROTECTION ENGINEERING CONTROLS Safety shower and eye bath. Mechanical exhaust required. PERSONAL PROTECTIVE EQUIPMENT Respiratory: Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection is desired, use multi purpose combination (US) or type ABEK (EN 14387) respirator cartridges. Hand: Compatible chemical-resistant gloves. Eye: Chemical safety goggles. GENERAL HYGIENE MEASURES Wash thoroughly after handling. Wash contaminated clothing before reuse.m-CLODROSOME www.clodrosome.com
  4. 4. ENCAPSULA NANOSCIENCES LLC MATERIAL SAFTEY DATA SHEET9. PHYSICAL AND CHEMICAL PROPERTIES Appearance White liquid dispersion Safety data pH 7.4 Melting point N/A Boiling point N/A Flash point N/A Ignition temperature N/A Lower explosion limit N/A Upper explosion limit N/A Water solubility N/A10. STABILTIY AND REACTIVITY Storage stability Can be stored for one month under nitrogen or argon at 4 °C. Materials to avoid Strong acids, Strong bases Hazardous decomposition products Hazardous decomposition products formed under fire conditions. – Carbon oxides, Oxides of phosphorus, Hydrogen chloride gas, Sodium oxides11. TOXICOLOGICAL INFORMATION ROUTE OF EXPOSURE Skin Contact: May cause skin irritation. Skin Absorption: May be harmful if absorbed through the skin. Eye Contact: May cause eye irritation. Inhalation: Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.m-CLODROSOME www.clodrosome.com
  5. 5. ENCAPSULA NANOSCIENCES LLC MATERIAL SAFTEY DATA SHEET Ingestion: May be harmful if swallowed. Chronic Exposure: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by ACGIH. NTP: No component of this product present at levels greater than or equal to 0.1% is identified as a known or anticipated carcinogen by NTP. OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. SIGNS AND SYMPTOMS OF EXPOSURE Nausea, Vomiting, Diarrhoea, Rash Potential Health Effects Inhalation May be harmful if inhaled. May cause respiratory tract irritation. Skin May be harmful if absorbed through skin. May cause skin irritation. Eyes May cause eye irritation. Ingestion May be harmful if swallowed. Target Organs Bone, Kidney, Additional Information RTECS: sz764070012. ECOLOGICAL INFORMATION Elimination information (persistence and degradability) N/A Ecotoxicity effects N/A Further information on ecology N/A13. DISPOSAL CONCIDERATIONS Product Observe all federal, state, and local environmental regulations. Contaminated packagingm-CLODROSOME www.clodrosome.com
  6. 6. ENCAPSULA NANOSCIENCES LLC MATERIAL SAFTEY DATA SHEET Dispose of as unused product.14. TRANSPORT INFORMATION DOT (US) Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods15. REGULATORY INFORMATION OSHA Hazards TARGET ORGAN EFFECT DSL Status This product contains the following components that are not on the Canadian DSL nor NDSL lists. Disodium dihydrogen (dichloromethylene)diphosphonate CAS-No. 22560-50-5 SARA 302 Components SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313. SARA 311/312 Hazards CHRONIC HEALTH HAZARD Massachusetts Right To Know Components No components are subject to the Massachusetts Right to Know Act. Pennsylvania Right To Know Components Lecithin AKA L-α-Phosphatidylcholine CAS-No. 8002-43-5 Cholesterol CAS-No. 55-88-5 4-AMINOPHENYL--D-MANNOPYRANOSIDE CAS No. 34213-86-0 New Jersey Right To Know Components Lecithin AKA L-α-Phosphatidylcholine CAS-No. 8002-43-5 Cholesterol CAS-No. 55-88-5 4-AMINOPHENYL--D-MANNOPYRANOSIDE CAS No. 34213-86-0 CLODRONATE CAS No. 22560-50-5 California Prop. 65 Componentsm-CLODROSOME www.clodrosome.com
  7. 7. ENCAPSULA NANOSCIENCES LLC MATERIAL SAFTEY DATA SHEET This product does not contain any chemicals known to State of California to cause cancer, birth, or any other reproductive defects.16. OTHER INFORMATION Further information Copyright 2009 Encapsula NanoSciences LLC license granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Encapsula NanoSciences LLC shall not be held liable for any damage resulting from handling or from contact with the above product.m-CLODROSOME www.clodrosome.com

×