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MSDS Cosmesome-Chol Containing Alcohol

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Material Safety Data Sheet (MSDS) for Cosmesome-Chol (containing alcohol). Proliposome formulation manufactured by Encapsula NanoSciences that is used specifically in the cosmetic industry. The brand name is Cosmesome-Chol. The Cosmesome-Chol formulation is composed of saturated phospholipids that form interdigitated lipids containing cholesterol in the presence of alcohol. The proliposome formulation forms liposomes upon dilution with water. During the dilution process water soluble active ingredients can be encapsulated inside the liposomes or liposoluble active ingredients can be incorporated into the lipid bilayers.

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MSDS Cosmesome-Chol Containing Alcohol

  1. 1. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 1. PRODUCT AND COMPANY IDENTIFICATION Product name: COSMESOME TM- Chol Product Number: COS-1001 Brand: COSMESOME TM Company Address: ENCAPSULA NANOSCIENCES LLC 6 CADILLAC DRIVE SUITE 245 BRENTWOOD, TN, 37027 Technical Phone: 615-884-4442 Fax: 615-250-8747 Emergency Phone: 615-438-8553 CHEMTREC: 1-800-424-9300 2. COMPOSITION/INFORMATION ON INGREDIENTS Ingredient Name CAS# Percent WATER 7732-18-5 >90 ETHANOL 64-17-5 <5 CHOLESTEROL 57-88-5 L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 <5 3. HAZARDS IDENTIFCATION OSHA No known OSHA hazards ENIECS: 200-353-2 HMIS RATING HEALTH HAZARDS: 1 FLAMMABILITY: 3 CHRONIC HEALTH HAZARDS: * PHYSICAL HAZARDS: 0 NFPA RATING HEALTH HAZARD: 1 FLAMMABILTY: 3 REACTIVITY: 0
  2. 2. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 POTENTIAL HEALTH EFFECTS Inhalation May be harmful if inhaled. May cause respiratory tract irritation to nose throat and respiratory tract. May result in central nervous system depression. May be irritating to the mucus membranes and upper respiratory tract. Skin May be harmful if absorbed through skin. May cause skin irritation. Eyes May cause eye irritation. Ingestion May be harmful if swallowed. May cause irritation of digestive tract and CNS depression (headache, drowsiness, loss of coordination and fatigue). May cause gastrointestinal irritation, nausea, vomiting and diarrhea. Chronic Preexisting skin, eye and respiratory disorders may be irritated by exposure to ethanol. 4. FIRST AID MEASURES ORAL EXPOSURE Do not induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician INHALATION EXPOSURE If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Do not use mouth to mouth resuscitation. Consult a physician. DERMAL EXPOSURE In case of contact, immediately wash skin with soap and copious amounts of water. Cover skin with an emollient. Contact a physician. EYE EXPOSURE In case of contact, check or remove any contact lenses; immediately flush eyes with copious amounts of water for at least 15 minutes. Contact a physician. INGESTION If victim is cautious and alert give 2-4 cupful’s of milk or water. Never give anything by mouth to an unconscious person. Get medical aide. 5. FIRE FIGHTING MEASURES FLAMMABILITY Highly combustible EXTINGUISHING MEDIA It is suitable to use water spray, alcohol -resistant foam, dry chemical or carbon dioxide. SPECIAL PROCTECTIVE EQUIPMENT FOR FIRE-FIGHTERS Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Included a positive pressure NIOSH approved self-contained breathing apparatus.
  3. 3. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 HAZARDOUS COMBUSTION PRODUCTS Hazardous decomposition products formed under fire conditions. Carbon oxides and Carbon Monoxide and other unidentified organic compounds may be formed during combustion. SPECIAL REMARKS Spontaneous ignition may occur when exposed to air and in contact with other materials such as cloth, paper, wood, insulation. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. 6. ACCIDENTAL RELEASE MEASURES METHODS FOR CLEANING UP Warring flammable. Eliminate all ignition sources, clean up personal, and require protective clothing and respiratory protection from vapors. Only specially trained or qualified personally should handle the emergency. Equipment must be grounded to prevent sparking. Contain liquid with absorbent material and place in non-leaky container. Seal tightly for disposal. Collect all clean up materials and dispose of them in accordance with local, state and federal waste disposal laws. ENVIRONMENTAL PRECAUTIONS Do not let product enter drains. If safe to do so prevent further leakages or spills. PERSONAL PRECAUTIONS Use personal protective equipment. Avoid breathing in vapors, mist or gas. Ensure adequate ventilation. Prepare evacuation sites. 7. HANDLING AND STORAGE HANDLING User Exposure: Do not breathe vapor, dust, fume, gas, mist and spray. Avoid prolonged or repeated exposure. Do not get in eyes, on skin, on clothing. Wash hands thoroughly after handling. STORAGE Suitable: Keep tightly container closed. Store in temperature between approximately 2-8 o C. Do not freeze keep in refrigerator. Product is sensitive to moisture and light. Keep product and empty container away from oxidizing materials. 8. EXPOSURE CONTROLS/ PERSONAL PROTECTION ENGINEERING CONTROLS Safety shower and eye bath. Mechanical exhaust required. PERSONAL PROTECTIVE EQUIPMENT Respiratory: Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) in accord with 29 CFR 1910.134 or EN 149, use either an atmosphere
  4. 4. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 supply respirator or air purifying respirator. Also follow face protection regulations in 29 CFR 1910.133 or European standard EN 166. Hand: Compatible chemical -resistant gloves. Eye: Chemical safety goggles. Skin and Body: Wear a complete suit protecting against chemicals. GENERAL HYGIENE MEASURES Wash hands thoroughly after handling. Wash contaminated clothing before reuse. Prepare all materials under the fume hood and avoid generating aerosols. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance white, viscous liquid Safety data N/A Melting point N/A Boiling point N/A Flash point N/A Ignition Temperature N/A Lower explosion limit N/A Upper Explosion limit N/A Water Solubility N/A Density N/A 10. STABILITY AND REACITIVITY STORAGE STABILITY Store under recommended conditions . MATERIALS TO AVIOD Strong oxidizing agents, strong acids
  5. 5. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 HAZARDOUS DECOMPOSITION PRODUCTS Hazardous decomposition products formed under fire conditions- Carbon Monoxide/Carbon dioxide and other unidentified organic compounds may be formed during combustion. Thermal decomposition can lead release or irritating gases and vapors. CONDITIONS TO AVOID Light and exposure to moisture. Incompatible product in excess heat. Avoid dust formation. 11. TOXICOLOGICAL INFORMATION CARCINOGENICITY This product contains a component that has been reported to be carcinogenic based on its IARC, OHSA, ACGIH, NTP, or EPA classification. IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by the IARC. OHSA: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by the OHSA. ACGIH: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by the ACGIH. EPA: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by the EPA. CHRONIC. Only select Reregister or Toxic of Chemical Substances (RTECS) data as presented here. See actual entry RTECS for complete information. RTECS number: FZ8400000. Product is harmful by ingestion. ACUTE TOXICITY ROUTE OF EXPOSURE Skin Contact: May cause skin irritation. May produce an allergic reaction. Skin Absorption: May be harmful if absorbed through the skin Eye Contact: May Cause eye irritation and risk serious damage Inhalation: Materials may be irritating to mucous membranes and upper respiratory tract. Ingestion: May be harmful if swallowed. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea. SIGNS AND SYMPTOMS OF EXPOSURE Symptoms have not be thoroughly investigated
  6. 6. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 12. ECOLOGICAL INFORMATION Elimination information (persistence and degradability) N/A Ecotoxicity effects N/A Further information on ecology N/A 13. DISPOSAL CONSIDERATIONS PRODUCT Observe all federal, state, and local environment regulations. Contact a licensed professional waste disposal service to remove this material. Do not pressurize, cut weld, solder, drill grind, or expose such containers to heat, flame, sparks, static electricity, or other sources or electricity. CONTAMINATED PACKAGING Dispose of as unused product. Preferred Method is to send licensed re-claimers or to permitted incinerators. Observe all federal, state, and local environment regulations. 14. TRANSPROT INFORMATION DOT (US) UN1170 Ethanol solution, 3, PG II IMDG Not dangerous goods IATA Not dangerous goods 15. REGULATORY INFORMATION OSHA HAZARDS OSHA: Hazardous by definition of Hazard Communication Standard (29 SFR 1910.1200). EINECS: this product is on the European Inventory of Existing Commercial Chemical Substances SARA 302 COMPONENTS SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302 SARA 313 COMPONENTS SARA 313: This material does not contain any chemical components with known CAS numbers that exceed threshold (De Minimis) reporting levels establi shed be SARA Title III, Section 313
  7. 7. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 SARA 311/312 HAZARDS Acute health hazards, chronic health hazards , fire hazard MASSACHUSETTS RIGHT TO KNOW COMPONENTS CAS-No. Revision Date Ethanol 64-17-5 2007-03-01 PENNSYVANIA RIGHT TO KNOW COMPONENTS CAS-No. Revision Date L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 1989-08-11 Ethanol 64-17-5 2007-03-01 Water 7732-18-5 Cholesterol 57-88-5 NEW JERSEY RIGHT TO KNOW COMPONENTS CAS-No. Revision Date L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 1989-08-11 Ethanol 64-17-5 2007-03-01 Water 7732-18-5 Cholesterol 57-88-5 CALIFORNIA PROP. 65 COMPONENTS CAS-No. Revision Date L-α-PHOSPHATIDYLCHOLINE, hydrogenated 97281-48-6 1989-08-11 U.S Department of Homeland Security This product does not contain any DHS chemicals WGK (Water Danger/Protection) CAS# 57-88-5: 1 TSCA CAS# 57-88-5 is listed TSCA inventory CAS# 7732185 is listed on the TSCA Inventory CANADA CAS# 7732185 is listed on Canada's DSL List 16. OTHER INFORMATION Copyright 2013 Encapsula NanoSciences LLC license granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not support to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is
  8. 8. Material Safety Data Sheet Version 1.1 Revision Date: 06/05/2014 Print Date: 08/06/2014 applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Encapsula NanoSciences LLC s hall not be held liable for any damage resulting from handling or from contact with the above product.

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