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The Effect of Intra-articular Injection of Autologous Microfragmented Fat Tissue on Proteogly can Synthesis in Patients with Knee Osteoarthritis
Damir Hudetz 1,2,3,*, Igor Borić 1,4,5, Eduard Rod 1, Željko Jeleč 1, Andrej Radić 1, Trpimir Vrdoljak 1,2, Andrea Skelin 1,6, Gordan Lauc 6,7,
A prospective, non-randomized, interventional, single-center, open-label clinical trial was conducted from January 2016 to April 2017
The results of our study indicate that the use of autologous and micro-fragmented adipose tissue in patients with knee OA (measured by dGEMRIC MRI) increased glycosaminoglycan (GAG) content in hyaline cartilage, which is in line with observed VAS and clinical results.