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Canterpene for-lifespan-healthspan-28-july-2012

  1. 1. REBRANDING HEMP FOR THE NUTRACEUTICAL MARKET CANTERPENE AS A HEALTHSPAN EXTENSION SUPPLEMENT
  2. 2. Terry Grossman,M.D. Medical Director Morris Johnson, CTO, Founder Silas Kanning, Co-founders of: Lifespan Pharma Inc.
  3. 3. OUR SHAREHOLDERS HAIL FROM AGRICULTURE, MEDICINE AND PHARMACY Morris/Greg/Leah/Erin Rod Fisher Steve Burnside
  4. 4. REBRANDING HEMP AS CANTERPENE MAKES SENSE FOR THE NATURAL HEALTH PRODUCT / DSHEA FOOD SUPPLEMENT MARKETS
  5. 5. 35 YEARS AGO RAPESEED EXPERIENCED THE SAME PROBLEMS AFFECTING HEMP TODAY Growers needed to rebrand something that was associated with a machine oil regarded as too toxic for humans to consume Low Erucic Acid Rapeseed (LEAR)? “CANadian source of OLeic Acid” became CANOLA It was promoted as a safe, nutritious, multi- purpose human and animal food ingredient
  6. 6. Hemp is undergoing a similar identity crisis in the minds of many today
  7. 7. When you Google “hemp” you get recreational and medicinal marijuana “Hits” because “pot people” use “hemp” indiscriminately when speaking about “marijuana”
  8. 8. SOME MARIJUANA PRODUCTS associate cannabis with health benefits and socially “sexy” memes such as organic or chemical free
  9. 9. SOME CANADIAN HEMP PRODUCTS ASSOCIATE HEMP WITH MARIJUANA
  10. 10. ASSOCIATING HEMP WITH MARIJUANA IS CREATING CONSUMER CONFUSION • Solutions: • Litigate? • Regulate? • Educate? • Ignore?
  11. 11. AFTER MUCH CONSIDERATION WE CONCLUDED NONE OF THE ABOVE SOLUTIONS ARE PRACTICAL OR COST EFFECTIVE Some hemp manufacturers want to capitalize on the science which has popularized the term “Medical Marijuana” The best solution: REBRANDING
  12. 12. REBRAND CANADIAN HEMP AS CANTERPENE We link Canadian Hemp with the messages: “Extend Health-span and Lifespan naturally with cannabis chemistry” Canterpene expands functional chemistry beyond arginine and omega3’s to include cannabinoids and terpenes
  13. 13. WE HAVE PATENTED CANTERPENE AS A PROPRIETARY FORMULATION OF MILLED HEMPSEED
  14. 14. DOES CANTERPENE HAVE A MARKET? -Healthspan and lifespan extension are new unmet needs -Personalized /Individualized Medicine is an emerging Industry -”Bockbuster” Pharma is migrating towards “Niche” Pharma -Canterpene Cannabis without THC contains phyto- chemistry which scientific research indicates would make it a useful food supplement for the purpose of personalized management of AGING
  15. 15. AGING CAN BE BRUTAL  This Becomes This--> All Too Soon
  16. 16. IT IS POSSIBLE TO GROW OLDER WITHOUT AGING AT ANY AGE 60 yrs old 80 yrs old
  17. 17. ANTIAGING IS AN ENORMOUS MARKET 76 million baby boomers in the US 6 million “boomies” in Canada Boomers now 48 – 64 and have begun to experience the “aging process” firsthand This generation has redefined each stage of their lives and is currently redefining aging
  18. 18. BOOMERS REGARD AGING IS A DISEASE …
  19. 19. … THAT AFFECTS EVERYONE
  20. 20. … AND IS 100 PERCENT FATAL
  21. 21. THIS IS THE NEW VIEW OF AGING Bob Delmonteque, age 84
  22. 22. THE TWO PILLARS OF HEALTH Prevention Early Detection
  23. 23. CANTERPENE CAN HELP AS A PREVENTIVE ANTIAGING STRATEGY Science has linked numerous Cannabis compounds found in Canterpene with beneficial effects on the diseases resulting from “normal” aging Canterpene captures much that other conventional hemp supplements have ignored
  24. 24. A toolbox for slowing aging & regenerating damage is emerging: e.g. Plastoquinine..targeting oxidative stress p
  25. 25. “TA65” targeting telomerase gene activation
  26. 26. Food supplements claiming to support stem cell healthspan STEMCELL100.COM , A NUTRACEUTICAL DEVELOPED BY GENESCIENT CLAIMS TO PROMOTE THE STABILITY AND VITALITY OF ADULT STEM CELLS SO THEY HAVE THE CAPACITY TO DIVIDE WHEN THE BODY SIGNALS A NEED FOR MORE STEM CELLS. CONTAINS: -THEANINE - 5-N-ETHYL-GLUTAMINE FROM CAMELLIA SINESIS -OLIGO-PROANTHOCYANIDINS FROM THE PINE BARK OF THE PINUS TREE -PTEROSTILBENE, WHICH IS A LONG HALF- LIFE RESVERATROL ANALOG FROM PTEROCARPUS MARSUPIUM - ASTRAGALOSIDES EXTRACTED FROM ASTRAGALUS MEMBRANACEUS
  27. 27. CAN CANTERPENE WORK AS A HEALTHSPAN AND LIFESPAN EXTENSION TOOL?
  28. 28. CANTERPENE THE MEDICAL BENEFITS
  29. 29. NUMEROUS BIOCHEMICAL BENEFITS OF CANNABINOIDS IN HEMP
  30. 30. Many terpenes exhibit health benefits Canterpene is a source of supplemental terpenes
  31. 31. Chemo-profiles of some cannabis varieties
  32. 32. AGING IS NOT LEGALLY CLASSIFIED AS A DISEASE But….
  33. 33. SOME DISEASES/CONDITIONS ASSOCIATED WITH AGING ARE Oxidative stress Arthritis Central nervous system degeneration Parkinson’s Alzheimer’s Cannabidiol (CBD) the major cannabinoid in hemp has been shown to be of benefit in each of these and many other conditions
  34. 34. OXIDATIVE STRESS CBD treatment significantly reduced oxidative stress; decreased the levels of tumor necrosis factor, vascular endothelial growth factor, and intercellular adhesion molecule-1; and prevented retinal cell death and vascular hyperpermeability in the diabetic retina. Consistent with these effects, CBD treatment also significantly inhibited p38 MAP kinase in the diabetic retina. These results demonstrate that CBD treatment reduces neurotoxicity, inflammation, and BRB breakdown in diabetic animals. EL Remessey AB et al. Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes. Am J Pathol. 2006 Jan;168(1):235-44.
  35. 35. ARTHRITIS These potentially anti-inflammatory properties of CBD, together with the lack of psychotropic effect and low toxicity prompted us to test the potential of CBD as a therapeutic agent in collagen-induced arthritis (CIA). RESULTS: “We report that CBD has a beneficial therapeutic action on established CIA.” Malfait AM et al. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9561-6.
  36. 36. PARKINSON’S DISEASE Evidence suggests that cannabinoids may prove useful in Parkinson's disease by inhibiting the excitotoxic neurotransmitter glutamate and counteracting oxidative damage to dopaminergic neurons Croxford JL. Therapeutic potential of cannabinoids in CNS disease. CNS Drugs. 2003;17(3):179-202. It seems that cannabinoids could delay or even stop progressive degeneration of brain dopaminergic systems, a process for which there is presently no prevention. In combination with currently used drugs, cannabinoids might represent, qualitatively, a new approach to the treatment of PD, making it more effective. Sevcik J, Masek K Potential role of cannabinoids in Parkinson's disease DRUG AGING 16 (6): 391-395 JUN 2000
  37. 37. ALZHEIMER’S DISEASE Memory loss, the first and primary symptom of Alzheimer’s disease, can be slowed down significantly in mice by cannabidiol. In a study at the Cajal Institute in Madrid, Spain, mice were injected with a molecule found in the brain of humans suffering from Alzheimer’s disease, and then treated for one week with cannabidiol. Those mice injected with cannabidiol successfully performed the task within 25-30 seconds, compared to control mice, who took almost double the amount of time, 45-50 seconds, to complete the task. See also: Iuvone T, Esposito G, Esposito R, et al. Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells J NEUROCHEM 89 (1): 134-141 APR 2004
  38. 38. DSHEA COMPLIANT TARGETS -Optimize the broad spectrum of Canterpene functionalities -Add phytochemistry to enhance each functionality -Utilize ingredients with both ethnobotanical and modern pharmacological support in peer-reviewed , published literature -Proprietary varietal selection and agronomic production practices allow the use of the same Canterpene ingredient for several distinctly different formulations -Formulas can be combined into a systemic therapeutic program to attack a systemic problem, AGING “Medicine without a market benefits no one”
  39. 39. DSHEA COMPLIANT TARGET 1 - Support for Cancer patients Synergistic with Conventional Meds. - Natural sourced ingredients: 1- 200mg Orange oil a source of limonene and perillic acid 2- 800mg Canterpene Hemp Oil
  40. 40. DSHEA COMPLIANT TARGET 1
  41. 41. DSHEA COMPLIANT TARGET 2 - Replacement of chemistry deficits caused by aging - Food supplement ingredients: -10 mg DHEA (dehydroepiandrosterone) to replace sex hormones required for sexual function, and lean muscular metabolism lost because of aging. - 200mg Acetyl L Carnitine to replace mental energy and endurance lost because of aging. -750mg Canterpene Hemp Oil to reduce subclinical inflammation associated with aging. -“SEXTROPY 4 U” BRANDING targets sexual health - Complementary to “Viagra” type of products
  42. 42. DSHEA COMPLIANT TARGET 2
  43. 43. DSHEA COMPLIANT TARGET 2
  44. 44. DSHEA COMPLIANT TARGET 3 Canterpene “hydrogen water” beverage -Hemp tea saturated with hydrogen gas -hydrogen water has been used therapeutically by several spas where the water has a natural hydrogen content -Malcolm dole detailed the anticancer properties of hydrogen in 1975 -hydrogen gas mixtures are used by deep divers -numerous papers detail the universal antioxidant properties of water with a hydrogen content -synergistic with the cannabinoid/terpene chemistry of hemp tea
  45. 45. DSHEA COMPLIANT TARGET 3
  46. 46. DSHEA COMPLIANT TARGET 3
  47. 47. DSHEA COMPLIANT TARGET 3
  48. 48. DSHEA COMPLIANT TARGET 4 Aging Metabolome/epigenome management Caragana -600 mg Soy Isoflavones -50 mg Canterpene -200 mg
  49. 49. DSHEA COMPLIANT TARGET 4
  50. 50. DSHEA COMPLIANT TARGET 4
  51. 51. DSHEA COMPLIANT TARGET 4
  52. 52. FUTURE RESEARCH TARGETS 5-Metabolic syndrome-diabetic process modulation: chelated vanadium flavonoid + fenugreek + Canterpene 6- telomerase modifier + Canterpene 7-CoQ10+plastoquinone +Canterpene 8-Epigenomic primer formula … Folic acid + B12 + Biotin+Canterpene 9-Arthritis/joint support formula- vitamin D + Canterpene + hops +MSM 10-Cardio support: 400 mg Acetyl-l-Carnitine, 500 mg Canterpene +100mg time released niacin 11-Microbiome Management: to enhance your macrocellular microflora to produce beneficial bioactives
  53. 53. GOOD SCIENCE WITHOUT A METHOD TO COMMERCIALIZE IT WILL NOT BENEFIT ANYONE CANTERPENE AS AN ANTIAGING STRATEGY
  54. 54. AGING , A SYSTEMIC DEGENERATIVE SYNDROME WITH MULTIPLE THERAPEUTIC TARGETS HTTP://WWW.YOUTUBE.COM/WATCH?V=GHVXW2EE3-A
  55. 55. CANTERPENE- A “MEDICAL EMANCIPATION” TOOL NUTRACEUTICALS THAT EMPOWER INDIVIDUALS TO PERSONALLY MANAGE THEIR HEALTHSPAN
  56. 56. The name of the game is to “beat this clock”
  57. 57. Lifespan Pharma Inc SW34-01-16-W2nd meridian Box 10 Beaubier, Sk., CANADA Lifespan.pharma.inc@gmail.com 701-240-9411
  58. 58. Original CANTERPENE concept Presented at : Canadian Hemp Trade Alliance Nov 15-17, 2010 Annual Conference Winnipeg , Manitoba , Canada

Editor's Notes

  • From Our Family to yours “ Live long and Prosper”.
  • Medicine can use the 12 step HACCP methodology to effectively deliver an integrated service Here I am with my partner Silas Kanning and Medical Director Terry Grossman who is a practitioner of leading edge integrated medicine
  • HACCP is not a quality or efficiency system but fully integrates with the Define/Measure/Analyze/Improve/Control cycles Open source access to knowledge Facilitates QA/QC and Lean
  • You assemble and direct your personal healthspan provider team  
  • What you plan to do with your life will determine the aggressiveness with which to apply your plan
  • ×