Molecular Genetics

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Molecular Genetics

  1. 1. Molecular Genetics Understanding the Role of Molecules in Inheritance Tuesday, March 9, 2010
  2. 2. Tuesday, March 9, 2010
  3. 3. Master Objectives: Tuesday, March 9, 2010
  4. 4. Master Objectives: 3.3.B.b Recognize that DNA codes for proteins, which are expressed as the heritable characteristics of an organism. (DOK: 1) Tuesday, March 9, 2010
  5. 5. Master Objectives: 3.3.B.b Recognize that DNA codes for proteins, which are expressed as the heritable characteristics of an organism. (DOK: 1) 3.3.B.e Identify possible external causes (e.g., heat, radiation, certain chemicals) and effects of DNA mutations (e.g., altered proteins which may affect chemical reactions and structural development). (DOK: 2) Tuesday, March 9, 2010
  6. 6. Tuesday, March 9, 2010
  7. 7. DNA provides the CODE Tuesday, March 9, 2010
  8. 8. DNA provides the CODE The sequence of nitrogen bases in DNA code for the building of protein Tuesday, March 9, 2010
  9. 9. DNA provides the CODE The sequence of nitrogen bases in DNA code for the building of protein Tuesday, March 9, 2010
  10. 10. DNA provides the CODE The sequence of nitrogen bases in DNA code for the building of protein The code (genes) are like a blueprint for constructing enzymes and cell parts Tuesday, March 9, 2010
  11. 11. Each strand of DNA contains many genes which each code for a different protein product Tuesday, March 9, 2010
  12. 12. Each strand of DNA contains many genes which each code for a different protein product Tuesday, March 9, 2010
  13. 13. Protein is made by linking AMINO ACIDS together Tuesday, March 9, 2010
  14. 14. Protein is made by linking AMINO ACIDS together Tuesday, March 9, 2010
  15. 15. Every 3 bases in DNA codes for a specific amino acid Tuesday, March 9, 2010
  16. 16. Every 3 bases in DNA codes for a specific amino acid Tuesday, March 9, 2010
  17. 17. The sequence of amino acids gives the protein its properties Tuesday, March 9, 2010
  18. 18. The sequence of amino acids gives the protein its properties Tuesday, March 9, 2010
  19. 19. Structural proteins and enzymes are responsible for ALL of our inherited characteristics Tuesday, March 9, 2010
  20. 20. Examples: Tuesday, March 9, 2010
  21. 21. Examples: antibodies Tuesday, March 9, 2010
  22. 22. Examples: keratin antibodies Tuesday, March 9, 2010
  23. 23. Examples: keratin hemoglobin antibodies Tuesday, March 9, 2010
  24. 24. Examples: keratin hemoglobin actin and myosin antibodies Tuesday, March 9, 2010
  25. 25. Examples: keratin hemoglobin actin and myosin antibodies pepsin and trypsin Tuesday, March 9, 2010
  26. 26. The Big Picture Tuesday, March 9, 2010
  27. 27. The Big Picture Central Dogma Tuesday, March 9, 2010
  28. 28. The Big Picture Protein Synthesis Central Dogma Tuesday, March 9, 2010
  29. 29. The Big Picture Protein Synthesis Central Dogma Tuesday, March 9, 2010
  30. 30. Tuesday, March 9, 2010
  31. 31. Tuesday, March 9, 2010
  32. 32. Mutations are changes in the DNA that alter protein synthesis. Tuesday, March 9, 2010
  33. 33. All mutation requires is a change in 1 base pair... Tuesday, March 9, 2010
  34. 34. All mutation requires is a change in 1 base pair... Chemicals Tuesday, March 9, 2010
  35. 35. All mutation requires is a change in 1 base pair... Chemicals UV Radiation Tuesday, March 9, 2010
  36. 36. All mutation requires is a change in 1 base pair... Nuclear Radiation Chemicals UV Radiation Tuesday, March 9, 2010
  37. 37. All mutation requires is a change in 1 base pair... Nuclear Radiation Mistakes Chemicals by the Cell UV Radiation Tuesday, March 9, 2010
  38. 38. All mutation requires is a change in 1 base pair... Nuclear Radiation Mistakes Chemicals by the Cell UV Radiation Carcinogens Tuesday, March 9, 2010
  39. 39. "DNA makes RNA and RNA makes proteins and proteins make us." ~Francis Crick Tuesday, March 9, 2010

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