The first part of my lectures will be devoted to the design of practical algorithms for very large graphs. The second part will be devoted to algorithms resilient to memory errors. Modern memory devices may suffer from faults, where some bits may arbitrarily flip and corrupt the values of the affected memory cells. The appearance of such faults may seriously compromise the correctness and performance of computations, and the larger is the memory usage the higher is the probability to incur into memory errors. In recent years, many algorithms for computing in the presence of memory faults have been introduced in the literature: in particular, an algorithm or a data structure is called resilient if it is able to work correctly on the set of uncorrupted values. This part will cover recent work on resilient algorithms and data structures.