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University of Missouri-Columbia, Cardiovascular Diagnosis from Ballistocardiogram

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Cardiovascular Diagnosis from Ballistocardiogram presented for Whiteboard2Boardroom on October 30, 2018

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University of Missouri-Columbia, Cardiovascular Diagnosis from Ballistocardiogram

  1. 1. Novel Method for Determining Aortic Compliance and Peripheral Resistance October 30, 2018
  2. 2. What is the problem? • High blood pressure can be caused by – Blockages in the arteries – Hardening of the arteries (arteriosclerosis) • Each cause requires a different treatment, but patients having high blood pressure are routinely treated for blockages or plaque buildup
  3. 3. How does product/service solve problem? • Giovanna Guidoboni developed a closed loop mathematical model that simulates the mechanisms generating the BCG signal 1 ln( / ) 1 1 ( / ) ln( / ) 1 ( / ) 1 For ... 3 2 . ln( / ) e e e e M S D T T T e S D T D e S D T T S D e S DS D S D V T T C P T P P V T T P P P T P P P P T T V C P PP P P P                1 ( / ) 1 ( / ) 1 For ... 3 . 3 e e e T T T M D e S D T T T S D e S D S D P T P T P P R V V P P T T P P P P T R V             
  4. 4. How does product/service solve problem? • By inputting blood pressure, heart rate, ejection period and stroke volume, we get – Aortic Capacitance (stiffness) – Peripheral resistance (blockage)
  5. 5. What is the market use? • Routine test for all patients suffering from high blood pressure
  6. 6. What competition exists? • Hypertension Diagnostics has a competing product
  7. 7. What is the status of the intellectual property? • Patent pending
  8. 8. What is the stage of development? • Must be tested with more data
  9. 9. What is needed for further development? • More validation with more patients • Determine if direct measurement of ejection period and stroke volume is necessary using an echocardiogram • Find an entrepreneur/licensee with cardiovascular expertise to assist in validation and/or a commercial deployment
  10. 10. Contact For more information please contact Jim Baxendale, Director of Whiteboard2Boardroom:baxendalej@umkc.edu.

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