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Whiteboard2Boardroom presents innovations from regional universities, hospitals, research organizations to encourage commercialization.

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Snap shot lever 2019 website version

  1. 1. Down the Hatch & Tongue Twister October 30, 2019
  2. 2. Clinical Need Problem: Subjectivity • Diagnostic tests • Treatment outcomes • No “common currency” SPEECH & SWALLOWING DISORDERS Need: Objectivity • Earlier disease detection • Improved diagnostic accuracy • Improved treatment monitoring • Discovery of better treatments EKG Body Mass IndexLab Tests
  3. 3. How does product/service solve problem? • Two Products 1. Down the Hatch: Medical device and software solution 2. Tongue Twister: Mobile Health Application (mHealth app)
  4. 4. What is the problem? Swallowing Impairment = Dysphagia Problem: Aspiration Pneumonia •Extended hospitalization •Re-hospitalization & associated Medicare fines •Poor quality of life •Leading cause of death (grossly under-estimated at 60 K Americans/year) Larynx
  5. 5. Solution: Down the Hatch Featured at the MU Innovation Dinner (October 12, 2017) Clinical tool to test the laryngeal reflex: Provides objective data to facilitate prediction and prevention of aspiration pneumonia
  6. 6. What is the market use? Who is it for? Clinicians who evaluate/treat dysphagia using endoscopy: Physicians (ENTs, GI, Pulmonology), Speech-language Pathologists (SLPs), and Veterinarians (>150,000 in the US) Why will they buy it? • Transforms endoscopic videos into objective and actionable data • Provides data visualization (numbers and graphs) during patient visits • Provides measurable outcomes to justify health insurance reimbursement • May reduce 30-day hospital re-admission rates and hefty Medicare fines associated with aspiration pneumonia diagnosis • Enables improved detection & tracking of laryngeal (upper airway) pathology and aspiration pneumonia risk • Results in more confident medical decision making -- eliminates clinicians’ reliance on subjective dysphagia rating scales and questionnaires
  7. 7. What competition exists? • Obsolete pre-existing devices: – No longer commercially available; no replacement parts – Air pulse delivery only, no analysis software – Low air pressure capability = underpowered; often fail to elicit the laryngeal reflex – Limited field of view = unable to see the entire reflex for objective motion analysis Competition Our Technology
  8. 8. What is the status of the intellectual property? • Patent pending • Not licensed to start-up yet
  9. 9. What is the stage of development? • 3 working prototypes - currently being used in normative studies • Analysis software automatically calculates – Reflex duration – Vocal fold motion • Symmetry • Synchrony • Distance • Velocity HorsesPeople 75 healthy adults 15 healthy adults Reflex duration
  10. 10. What is needed for further development? • Identify a start-up business partner who will: – Assist with product refinement & commercialization – Provide business, marketing, & finance advice • Apply for SBIR/STTR grant funding – Clinical validation – Device and software refinement People with dysphagia Parkinson’s Disease Head & Neck Cancer Horses at high risk for airway collapse due to laryngeal disease Thoroughbreds Draft horses Single clinician operator Identify additional outcome measures and complete validation
  11. 11. QUESTIONS?
  12. 12. Switching Gears Down the Hatch Tongue Twister Swallowing Speech & Swallowing
  13. 13. What is the problem? Speech & Swallowing Impairment Problem: Clinical assessment and treatment intervention protocols are qualitative and subjective
  14. 14. Solution: Tongue Twister Mobile Health App that provides objective data for speech & swallow tasks that are routinely used in clinical practice world-wide Can be used as the basis for a number of diagnostic tools related to speech and swallowing dysfunction. Merged audio/video
  15. 15. What is the market use? Who is it for? Clinicians who diagnose and treat speech and swallowing disorders (e.g., neurologists, ENTs, SLPs), and patients with speech and swallowing disorders Why will they buy it?
  16. 16. What competition exists? Speech & Swallowing Assessment Event Detection Accuracy Event Recognition Accuracy Clinician- interactive Mode Automated data analysis Graphic Output of Data PENTAX Medical (software, 2008) PRAAT (software, 1991) SPEECHLIGHT (app, 2017) SwallowTail (software, 2017) Our Technology Separate tools Combined Speech only Swallow only Speech only >90% >80%
  17. 17. What is the status of the intellectual property? • Patent-pending • Not licensed to start-up yet
  18. 18. What is the stage of development? • Mobile health app on iPad for audio/visual recording of speech/swallow tasks • Separate analytics software • App and software are currently in use: – Normative study (>200 healthy adults, 20-90 years old) – Parkinson’s disease (29 patients tested thus far)
  19. 19. What is needed for further development? • Identify a start-up business partner who will: – Assist with product refinement & commercialization – Provide business, marketing, & finance advice • Apply for SBIR/STTR funding – Clinical validation: Parkinson’s disease – Device and software development/refinement Merge app & analytics software Improve recognition accuracy Develop cloud analytics
  20. 20. QUESTIONS?

Whiteboard2Boardroom presents innovations from regional universities, hospitals, research organizations to encourage commercialization.

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