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Increasing
                                 Glaucoma Awareness
                                Through the Vision Care
                                Channel with Glycemion


                                            A Proposal to




Konstantine Haralampopoulos   August 2008
Execution Process for Opportunity: Pfizer / Glaucoma / Xalatan®


Glycemion (Konstantine)                                 Pfizer                            TOS                       Dr. / Patients

                                            6                                9                                 12
      1
          Identify Opportunity*                         Purchases                Contact each participating           Patient receives
      (Industry / Sponsor / Contact)              estimated number of              practice / Dr., assist       personalized letter from their
                                                test kits from Glycemion            with PatientMiner            Dr. w/ call to action / offer

      2       Create sample letter &
              presentation materials        7                                10                                13
                                                                                                                    Patient stimulated to
                                              Sales force orientation              Reporting of program
                                                                                                                    make appt. with Dr.,
                                            conference call led by TOS              status to sponsor
                                                                                                                    mentions letter / offer
                    Existing           NO
                   Glycemion
  YES
                    contact?
                                            8 Sales Reps present opp.        11
 3                                               to Drs. (optometrists),          TOS receives payment              = Glycemion involvement
  Glycemion                                      leverage commitment,                from sponsor
   provides                                     provide Kits, sign-up Drs.
 introduction


                                            * Pfizer / Glaucoma / Xalatan® Opportunity
      4
              presents opportunity
                                            Benefits to Pfizer:
                                            Raise awareness of dangers and prevalence of age related diseases such as glaucoma and
                                            diabetes in a targeted patient group (aged 45+ and due for an eye exam) through personalized
                                            messages from eye doctors. Messaging can stress the possible link between diabetes and
     NO             Sponsor                 glaucoma and the importance of regular eye exams in early detection.
                   agrees to
                   Pilot Test?              Benefit to Optometrists: Increased patient traffic and appointments through targeted
                                            personalized letters/brochures to patients overdue for an eye exam.
                                            Benefit to patients: Receive a free DRA kit and/or referral to a (Xalatan prescribing) MD if
                           YES
                                            determined by optometrist that patient may be pre-diabetic or showing signs of glaucoma.
          5  TOS contracts with             Benefit to Glycemion: Has DRA kits underwritten (i.e. paid for) and gets brand entrenched
          sponsor, provides test plan       as THE screen test for pre-diabetes
           and orientation materials
Execution Process for Opportunity: Pfizer / Glaucoma / Xalatan®


                   Glycemion                               Pfizer                              TOS                      Dr. / Patients

                                               6                                  9                                7
        1
            Identify Opportunity*                          Purchases                  Contact each participating         Patient receives
        (Industry / Sponsor / Contact)               estimated number of                practice / Dr., assist     personalized letter from their
                                                   test kits from Glycemion              with PatientMiner          Dr. w/ call to action / offer

        2        Create sample letter &
                 presentation materials        7                                 10                                13
                                                                                                                        Patient stimulated to
                                                 Sales force orientation                Reporting of program
                                                                                                                        make appt. with Dr.,
                                               conference call led by TOS                status to sponsor
                                                                                                                        mentions letter / offer
                       Existing           NO
                      Glycemion
    YES
                       contact?
                                               8 Sales Reps present opp.         11
   3                                                to Drs. (optometrists),            TOS receives payment             = Glycemion involvement
Glycemion provides                                  leverage commitment,                  from sponsor
   introduction                                    provide Kits, sign-up Drs.


                                               SAY:                                           SHOW: (Letter)           SUBMIT: (Auth Form)
        4                                      "We'd like to sponsor a targeted HIPAA-
                And presents opportunity
                                               compliant patient communication
                                               program that will stimulate patients to
                                               come into your office for their regular eye
                                               exam. Personalized letters from your
       NO              Sponsor                 practice will be sent out to targeted
                      agrees to
                                               patients 45+ that are due for an exam.
                      Pilot Test?
                                               The letters will discuss the symptomless
                                               beginnings of diabetes & glaucoma and
                              YES              the importance of regular eye exams for
            5                                  early diagnosis.
               TOS contracts with
                                               A free DRA kit will be offered as an
            sponsor, provides test plan
             and orientation materials         additional call to action.”


                                                                                                                                                    .

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Glycemion / Pfizer Presentation For Eye Disease Screening

  • 1. Increasing Glaucoma Awareness Through the Vision Care Channel with Glycemion A Proposal to Konstantine Haralampopoulos August 2008
  • 2. Execution Process for Opportunity: Pfizer / Glaucoma / Xalatan® Glycemion (Konstantine) Pfizer TOS Dr. / Patients 6 9 12 1 Identify Opportunity* Purchases Contact each participating Patient receives (Industry / Sponsor / Contact) estimated number of practice / Dr., assist personalized letter from their test kits from Glycemion with PatientMiner Dr. w/ call to action / offer 2 Create sample letter & presentation materials 7 10 13 Patient stimulated to Sales force orientation Reporting of program make appt. with Dr., conference call led by TOS status to sponsor mentions letter / offer Existing NO Glycemion YES contact? 8 Sales Reps present opp. 11 3 to Drs. (optometrists), TOS receives payment = Glycemion involvement Glycemion leverage commitment, from sponsor provides provide Kits, sign-up Drs. introduction * Pfizer / Glaucoma / Xalatan® Opportunity 4 presents opportunity Benefits to Pfizer: Raise awareness of dangers and prevalence of age related diseases such as glaucoma and diabetes in a targeted patient group (aged 45+ and due for an eye exam) through personalized messages from eye doctors. Messaging can stress the possible link between diabetes and NO Sponsor glaucoma and the importance of regular eye exams in early detection. agrees to Pilot Test? Benefit to Optometrists: Increased patient traffic and appointments through targeted personalized letters/brochures to patients overdue for an eye exam. Benefit to patients: Receive a free DRA kit and/or referral to a (Xalatan prescribing) MD if YES determined by optometrist that patient may be pre-diabetic or showing signs of glaucoma. 5 TOS contracts with Benefit to Glycemion: Has DRA kits underwritten (i.e. paid for) and gets brand entrenched sponsor, provides test plan as THE screen test for pre-diabetes and orientation materials
  • 3. Execution Process for Opportunity: Pfizer / Glaucoma / Xalatan® Glycemion Pfizer TOS Dr. / Patients 6 9 7 1 Identify Opportunity* Purchases Contact each participating Patient receives (Industry / Sponsor / Contact) estimated number of practice / Dr., assist personalized letter from their test kits from Glycemion with PatientMiner Dr. w/ call to action / offer 2 Create sample letter & presentation materials 7 10 13 Patient stimulated to Sales force orientation Reporting of program make appt. with Dr., conference call led by TOS status to sponsor mentions letter / offer Existing NO Glycemion YES contact? 8 Sales Reps present opp. 11 3 to Drs. (optometrists), TOS receives payment = Glycemion involvement Glycemion provides leverage commitment, from sponsor introduction provide Kits, sign-up Drs. SAY: SHOW: (Letter) SUBMIT: (Auth Form) 4 "We'd like to sponsor a targeted HIPAA- And presents opportunity compliant patient communication program that will stimulate patients to come into your office for their regular eye exam. Personalized letters from your NO Sponsor practice will be sent out to targeted agrees to patients 45+ that are due for an exam. Pilot Test? The letters will discuss the symptomless beginnings of diabetes & glaucoma and YES the importance of regular eye exams for 5 early diagnosis. TOS contracts with A free DRA kit will be offered as an sponsor, provides test plan and orientation materials additional call to action.” .