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The Legacy of NHS London
         Stroke
          Tony Rudd
 London Stroke Clinical Director
St Thomas’ Hospital
St Thomas’ Hospital stroke care in 1988

 Patients admitted under care of any of 17 general
  physicians to any one of 15 wards
 Very little happened acutely
 Brain scans difficult to obtain and therefore rarely
  done
 Referred to geriatricians for rehabilitation – long wait
 No stroke specialist service either in hospital or
  community
Sentinel Stroke Audit 2010. RCP London
30 Day Mortality Over Time
               30

               25

               20
 % of patients
who died within 15
   30 days
                10

                5

                0
                     2004     2006             2008             2010
                                  Year of Audit



                            Sentinel Stroke Audit 2010. RCP London
BUT despite this......
The case for changing stroke care
                                                                                                                                                             Above Target

London Stroke Units Sentinel Audit Comparison 2004 and 2006                                                                                                  Below Target
                                                                                                                                                               Target
                            91 90 89 88 88 86 84
                                                 83 80 80
                       90                                 77 76 76 75 72 71 71 71
                                                                                  70 70 68 68 66 65 65
                                                                                                       62 61 60
   London Stroke
   Providers against
                                                                                                                55 51
                                                                                                                      49 45
   Sentinel Audit 12
   key indicators
   2006




                            25   25
                                      24
                                           21   21
   Change in London                                  19   19
   Stroke Providers
   against Sentinel                                            14
   Audit 12 key                                                     12   12
   indicators                                                                 9   9
                                                                                      8
   2006 vs 2004                                                                           6   6
                                                                                                  5
   scores                                                                                             4   4
                                                                                                              2
                                                                                                                  1
                                                                                                                      0

                                                                                                                          -1
                                                                                                                               -3   -3
                                                                                                                                         -4   -4
                                                                                                                                                   -5
                                                                                                                                                        -7
                                                                                                                                                              -9
                                                                                                                                                                   -12
The scale of the problem of stroke in London




• Second biggest killer and most common cause of disability
• Population >8 million
• 11,500 strokes a year in London – 2,000 deaths
Availability of potential stroke providers

                              Theoretical Catchments Area Overlap
                              for current Stroke Providers
                                  12 to 14 Providers Overlapping
                                  10 to 12 Providers Overlapping
                                   8 to 10 Providers Overlapping
                                   6 to 8 Providers Overlapping
                                   4 to 6 Providers Overlapping
                                   2 to 4 Providers Overlapping




                              •      The more intense the
                                     red the greater number
                                     of providers available
                                     to provide service to
                                     the area.

                              •      There is always at least
                                     two providers available
                                     to any give area.
Decision to reorganise care
   National Stroke Strategy
   National Stroke Audit
   Darzi review of medical care in London
   Lobbying from London Stroke community
   Ruth Carnall and SHA choosing stroke and major
    trauma
     Clear case for change
        Good evidence as to what should be done
        A clinical community wanting to see change
Stroke pathway
                                                                       Access to leisure,
                               Stroke    Tailored       Self care/
 Primary    Rapid       Thromb                                              Employment,
                                Unit      Community     Peer support
Prevention detection   -olysis                                                Other
                                care      rehab        Sign posting
                                                                        opportunities


                         Quality information for users and carers

                           Quality information for professionals

                 A workforce skilled in working with people with stroke

                            Preventing a further stroke or TIA




 Acute phase recovery Learning to live with a                Living with a disability
                            disability
Process for implementing change
 Agreement from all London PCTs and formation
  of JCPCT to support the process and to invest
  additional £20m/annum
 Project board with representation from
  commissioners, networks, clinicians, managers,
  patients, voluntary groups
 Whole system reorganisation
 Split care into hyperacute, acute, transient
  ischaemic attack and community care
Process for implementing change
 Setting the standards based on evidence
 Development of range of models – consultation
  with professionals
 Agreement that additional funding paid as
  enhanced tariff if quality standards met
 Agreement on splitting tariff
 Setting of stages of quality standards with
  increasing proportions of enhanced tariff paid at
  each level
Process for implementing change
 Bidding process for delivery of HASU, SU and TIA
  care. Requiring close collaboration between
  managers and clinicians from each provider
 External review of applications
 Final decision on allocation of services made by
  SHA based on geography more than quality
Final model
 8 HASUs each with their own SUs
    124 HASU beds
 Further 16 SUs
 24 TIA services
 Repatriation where needed up to 72 hours
  (longer if too unstable to transfer). Financial
  incentives to move rapidly after referral
 400 additional nurses needed and about 100
  therapists
30-minute blue light ambulance travel time from
          the hyper-acute stroke units




The green area shows the areas that are within 30 minutes travel time
(under ambulance blue light conditions) of a proposed HASU
Standards
 Predefined minimum rotas for doctors
 Requirement at least daily consultant rounds on
  HASUs
 Minimum staffing levels for therapists and nurses
 About 60 criteria against which quality of care
  measured
Implementation of plan
 London Stroke and Cardiac Board
 Role of networks and clinical director
    Supporting change
    Inspecting services with commissioners to decide
     if eligible for enhanced tariff
    Education/training
    Daily activity and performance management
• Development of local leaders
• Obligation to submit continuous audit
Successes
 All HASUs now fully open and working effectively
 All SUs passed A1 and A2 criteria
 Virtually all patients directly accessing high
  quality acute care
   Admission to HASU
   Thrombolysis where appropriate
   Consultant led specialist medical care, stroke specialist
    nursing care and early access to stroke therapists from
    the beginning
Successes
 Excellent collaboration between clinicians across
  London
 Innovative training initiatives
 Closer collaboration between managers,
  paramedics, hospital clinicians, community
  clinicians, network staff and commissioners
  working in stroke than ever achieved before
 Good patient feedback
Workforce initiatives
 E-learning programme nearly complete (Imperial
  College)
 Simulation centre courses developed and running at
  4 of SIM Centres in London
    Senior doctors and nurses
    Band 5 nurses and junior doctors
 Conferences for paramedics
 Competencies developed for HASU and SU nurses
Early supported discharge
 Most areas now have access to a service or at the
  stage of commissioning a service
 Longer term rehabilitation
   Service provision variable
Evaluation of the reconfiguration
 Process data from
     London Ambulance Service
     SINAP
     London Minimum Dataset
     Vital signs data
 SDO NIHR funded study
 NHS London Health Economic study
Journey times
        Avg Time from Scene to Hospital

20.00

18.00                                     Charing Cross
16.00                                     King`s College

14.00                                     Northwick Park
                                          Princess Ryl Hosp, Farnborough
12.00
                                          Queens Hospital, Romford
10.00
                                          Ryl London (Whitechapel)
 8.00
                                          St Georges, Tooting
 6.00                                     St Thomas`
 4.00                                     University College
                                          Overall Average
 2.00

 0.00
              Apr-10
HASU destination on discharge
60%



50%



40%



30%



20%



10%


0%
      Home   Other   Stroke Unit   RIP
Processes of care
                            Thrombolysis rates
                                                             18%

16%

14%                                      14%
12%                           12%
10%

8%                    10%
6%

4%
         3.5%
2%

0%

      Feb-July 2009   Aim Feb-July 2010 Jan-March 2011   Jan-July 2012
Processes of care
                   Average length of stay

20

18

16

14

12

10

8

6

4

2

0
     Apr May Jun   Jul   Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun     Jul   Aug

                             2009/10                           2010/11
London stroke survival vs rest of
           England




            Hazard ratio for survival in London
            0.72 95%CI 0.67-0.77 p<0.001
Cost-effectiveness analysis of the London Stroke Service:
         results based on 6438 strokes per annum
                                                    Professor Steve Morris et al

Differences in                                  Unadjusted               Adjusted
Differences in total costs at 30 days           3,307,677                3,763,472
Differences in total deaths at 30 days             -214                        -68
Differences in total QALYs at 30 days               51                         44
Incremental cost per death averted at 30 days     15,451                    55,371
Incremental cost per QALY gained at 30 days       64,478                    86,106
Differences in total costs at 90 days           -5,393,533              -3,544,210
Differences in total deaths at 90 days             -238                        -98
Differences in total QALYs at 90 days              112                         86
Incremental cost per death averted at 90 days    Dominant                Dominant
Incremental cost per QALY gained at 90 days      Dominant                Dominant
Differences in total costs at 10 years          -21,318,180            -22,786,954
Differences in total QALYs at 10 years            4,492                      3,886
Incremental cost per QALY gained at 10 years     Dominant                Dominant
Cost-effectiveness analysis of the London Stroke
       Service: results based on 6438 strokes per annum
Differences in                                  Unadjusted     Adjusted
Differences in total costs at 30 days           3,307,677     3,763,472
Differences in total deaths at 30 days             -214           -68
Differences in total QALYs at 30 days               51            44
Incremental cost per death averted at 30 days     15,451        55,371
Incremental cost per QALY gained at 30 days       64,478        86,106
Differences in total costs at 90 days           -5,393,533    -3,544,210
Differences in total deaths at 90 days             -238           -98
Differences in total QALYs at 90 days              112            86
Incremental cost per death averted at 90 days   Dominant      Dominant
Incremental cost per QALY gained at 90 days     Dominant      Dominant
Differences in total costs at 10 years          -21,318,180   -22,786,954
Differences in total QALYs at 90 days             4,492         3,886
Incremental cost per QALY gained at 10 years     Dominant      Dominant
Cost-effectiveness analysis of the London Stroke
      Service: results based on 6438 strokes per annum
Differences in                                  Unadjusted     Adjusted
Differences in total costs at 30 days           3,307,677     3,763,472
Differences in total deaths at 30 days             -214           -68
Differences in total QALYs at 30 days               51            44
Incremental cost per death averted at 30 days     15,451        55,371
Incremental cost per QALY gained at 30 days       64,478        86,106
Differences in total costs at 90 days           -5,393,533    -3,544,210
Differences in total deaths at 90 days             -238           -98
Differences in total QALYs at 90 days              112            86
Incremental cost per death averted at 90 days    Dominant      Dominant
Incremental cost per QALY gained at 90 days      Dominant      Dominant
Differences in total costs at 10 years          -21,318,180   -22,786,954
Differences in total QALYs at 90 days             4,492         3,886
Incremental cost per QALY gained at 10 years    Dominant      Dominant
Sensitivity analysis
Results were qualitatively unchanged after
undertaking sensitivity analysis on the following:
   •   Stroke mimics
   •   LOS in the HASU
   •   Unit cost per day in the HASU
   •   LOS in ICU
   •   Neurosurgery rates
   •   Discharge destinations
What next?
 Much more work on latter part of pathway
 Development of similar model in Midlands and East
  of England and review of Manchester model
 Keeping going.....
How do we stop everything
              unravelling?
 How do we persuade CCGs to continue the enhanced
  tariff?
 How do we keep control of quality and stop trusts cutting
  resources?
 How do we maintain the close relationship that has
  developed between commissioners and providers that
  has been fostered by networks?
 Who will retain oversight and retain responsibility for
  London stroke?

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Tony Rudd: the legacy of NHS London - stroke programme

  • 1. The Legacy of NHS London Stroke Tony Rudd London Stroke Clinical Director
  • 3. St Thomas’ Hospital stroke care in 1988  Patients admitted under care of any of 17 general physicians to any one of 15 wards  Very little happened acutely  Brain scans difficult to obtain and therefore rarely done  Referred to geriatricians for rehabilitation – long wait  No stroke specialist service either in hospital or community
  • 4. Sentinel Stroke Audit 2010. RCP London
  • 5. 30 Day Mortality Over Time 30 25 20 % of patients who died within 15 30 days 10 5 0 2004 2006 2008 2010 Year of Audit Sentinel Stroke Audit 2010. RCP London
  • 6.
  • 8. The case for changing stroke care Above Target London Stroke Units Sentinel Audit Comparison 2004 and 2006 Below Target Target 91 90 89 88 88 86 84 83 80 80 90 77 76 76 75 72 71 71 71 70 70 68 68 66 65 65 62 61 60 London Stroke Providers against 55 51 49 45 Sentinel Audit 12 key indicators 2006 25 25 24 21 21 Change in London 19 19 Stroke Providers against Sentinel 14 Audit 12 key 12 12 indicators 9 9 8 2006 vs 2004 6 6 5 scores 4 4 2 1 0 -1 -3 -3 -4 -4 -5 -7 -9 -12
  • 9. The scale of the problem of stroke in London • Second biggest killer and most common cause of disability • Population >8 million • 11,500 strokes a year in London – 2,000 deaths
  • 10. Availability of potential stroke providers Theoretical Catchments Area Overlap for current Stroke Providers 12 to 14 Providers Overlapping 10 to 12 Providers Overlapping 8 to 10 Providers Overlapping 6 to 8 Providers Overlapping 4 to 6 Providers Overlapping 2 to 4 Providers Overlapping • The more intense the red the greater number of providers available to provide service to the area. • There is always at least two providers available to any give area.
  • 11. Decision to reorganise care  National Stroke Strategy  National Stroke Audit  Darzi review of medical care in London  Lobbying from London Stroke community  Ruth Carnall and SHA choosing stroke and major trauma  Clear case for change  Good evidence as to what should be done  A clinical community wanting to see change
  • 12. Stroke pathway Access to leisure, Stroke Tailored Self care/ Primary Rapid Thromb Employment, Unit Community Peer support Prevention detection -olysis Other care rehab Sign posting opportunities Quality information for users and carers Quality information for professionals A workforce skilled in working with people with stroke Preventing a further stroke or TIA Acute phase recovery Learning to live with a Living with a disability disability
  • 13. Process for implementing change  Agreement from all London PCTs and formation of JCPCT to support the process and to invest additional £20m/annum  Project board with representation from commissioners, networks, clinicians, managers, patients, voluntary groups  Whole system reorganisation  Split care into hyperacute, acute, transient ischaemic attack and community care
  • 14. Process for implementing change  Setting the standards based on evidence  Development of range of models – consultation with professionals  Agreement that additional funding paid as enhanced tariff if quality standards met  Agreement on splitting tariff  Setting of stages of quality standards with increasing proportions of enhanced tariff paid at each level
  • 15. Process for implementing change  Bidding process for delivery of HASU, SU and TIA care. Requiring close collaboration between managers and clinicians from each provider  External review of applications  Final decision on allocation of services made by SHA based on geography more than quality
  • 16. Final model  8 HASUs each with their own SUs  124 HASU beds  Further 16 SUs  24 TIA services  Repatriation where needed up to 72 hours (longer if too unstable to transfer). Financial incentives to move rapidly after referral  400 additional nurses needed and about 100 therapists
  • 17. 30-minute blue light ambulance travel time from the hyper-acute stroke units The green area shows the areas that are within 30 minutes travel time (under ambulance blue light conditions) of a proposed HASU
  • 18. Standards  Predefined minimum rotas for doctors  Requirement at least daily consultant rounds on HASUs  Minimum staffing levels for therapists and nurses  About 60 criteria against which quality of care measured
  • 19. Implementation of plan  London Stroke and Cardiac Board  Role of networks and clinical director  Supporting change  Inspecting services with commissioners to decide if eligible for enhanced tariff  Education/training  Daily activity and performance management • Development of local leaders • Obligation to submit continuous audit
  • 20. Successes  All HASUs now fully open and working effectively  All SUs passed A1 and A2 criteria  Virtually all patients directly accessing high quality acute care  Admission to HASU  Thrombolysis where appropriate  Consultant led specialist medical care, stroke specialist nursing care and early access to stroke therapists from the beginning
  • 21. Successes  Excellent collaboration between clinicians across London  Innovative training initiatives  Closer collaboration between managers, paramedics, hospital clinicians, community clinicians, network staff and commissioners working in stroke than ever achieved before  Good patient feedback
  • 22. Workforce initiatives  E-learning programme nearly complete (Imperial College)  Simulation centre courses developed and running at 4 of SIM Centres in London  Senior doctors and nurses  Band 5 nurses and junior doctors  Conferences for paramedics  Competencies developed for HASU and SU nurses
  • 23. Early supported discharge  Most areas now have access to a service or at the stage of commissioning a service  Longer term rehabilitation  Service provision variable
  • 24. Evaluation of the reconfiguration  Process data from  London Ambulance Service  SINAP  London Minimum Dataset  Vital signs data  SDO NIHR funded study  NHS London Health Economic study
  • 25. Journey times Avg Time from Scene to Hospital 20.00 18.00 Charing Cross 16.00 King`s College 14.00 Northwick Park Princess Ryl Hosp, Farnborough 12.00 Queens Hospital, Romford 10.00 Ryl London (Whitechapel) 8.00 St Georges, Tooting 6.00 St Thomas` 4.00 University College Overall Average 2.00 0.00 Apr-10
  • 26. HASU destination on discharge 60% 50% 40% 30% 20% 10% 0% Home Other Stroke Unit RIP
  • 27. Processes of care Thrombolysis rates 18% 16% 14% 14% 12% 12% 10% 8% 10% 6% 4% 3.5% 2% 0% Feb-July 2009 Aim Feb-July 2010 Jan-March 2011 Jan-July 2012
  • 28. Processes of care Average length of stay 20 18 16 14 12 10 8 6 4 2 0 Apr May Jun Jul Aug Sep Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug 2009/10 2010/11
  • 29. London stroke survival vs rest of England Hazard ratio for survival in London 0.72 95%CI 0.67-0.77 p<0.001
  • 30. Cost-effectiveness analysis of the London Stroke Service: results based on 6438 strokes per annum Professor Steve Morris et al Differences in Unadjusted Adjusted Differences in total costs at 30 days 3,307,677 3,763,472 Differences in total deaths at 30 days -214 -68 Differences in total QALYs at 30 days 51 44 Incremental cost per death averted at 30 days 15,451 55,371 Incremental cost per QALY gained at 30 days 64,478 86,106 Differences in total costs at 90 days -5,393,533 -3,544,210 Differences in total deaths at 90 days -238 -98 Differences in total QALYs at 90 days 112 86 Incremental cost per death averted at 90 days Dominant Dominant Incremental cost per QALY gained at 90 days Dominant Dominant Differences in total costs at 10 years -21,318,180 -22,786,954 Differences in total QALYs at 10 years 4,492 3,886 Incremental cost per QALY gained at 10 years Dominant Dominant
  • 31. Cost-effectiveness analysis of the London Stroke Service: results based on 6438 strokes per annum Differences in Unadjusted Adjusted Differences in total costs at 30 days 3,307,677 3,763,472 Differences in total deaths at 30 days -214 -68 Differences in total QALYs at 30 days 51 44 Incremental cost per death averted at 30 days 15,451 55,371 Incremental cost per QALY gained at 30 days 64,478 86,106 Differences in total costs at 90 days -5,393,533 -3,544,210 Differences in total deaths at 90 days -238 -98 Differences in total QALYs at 90 days 112 86 Incremental cost per death averted at 90 days Dominant Dominant Incremental cost per QALY gained at 90 days Dominant Dominant Differences in total costs at 10 years -21,318,180 -22,786,954 Differences in total QALYs at 90 days 4,492 3,886 Incremental cost per QALY gained at 10 years Dominant Dominant
  • 32. Cost-effectiveness analysis of the London Stroke Service: results based on 6438 strokes per annum Differences in Unadjusted Adjusted Differences in total costs at 30 days 3,307,677 3,763,472 Differences in total deaths at 30 days -214 -68 Differences in total QALYs at 30 days 51 44 Incremental cost per death averted at 30 days 15,451 55,371 Incremental cost per QALY gained at 30 days 64,478 86,106 Differences in total costs at 90 days -5,393,533 -3,544,210 Differences in total deaths at 90 days -238 -98 Differences in total QALYs at 90 days 112 86 Incremental cost per death averted at 90 days Dominant Dominant Incremental cost per QALY gained at 90 days Dominant Dominant Differences in total costs at 10 years -21,318,180 -22,786,954 Differences in total QALYs at 90 days 4,492 3,886 Incremental cost per QALY gained at 10 years Dominant Dominant
  • 33. Sensitivity analysis Results were qualitatively unchanged after undertaking sensitivity analysis on the following: • Stroke mimics • LOS in the HASU • Unit cost per day in the HASU • LOS in ICU • Neurosurgery rates • Discharge destinations
  • 34. What next?  Much more work on latter part of pathway  Development of similar model in Midlands and East of England and review of Manchester model  Keeping going.....
  • 35. How do we stop everything unravelling?  How do we persuade CCGs to continue the enhanced tariff?  How do we keep control of quality and stop trusts cutting resources?  How do we maintain the close relationship that has developed between commissioners and providers that has been fostered by networks?  Who will retain oversight and retain responsibility for London stroke?

Editor's Notes

  1. In complete opposite to major trauma, most cases of stroke occur in the suburbs – where older people tend to live. The next two most important factors in stroke are i) ethnicity (there is a 60% greater incidence of stroke within the black African and black Caribbean populations than the white population and ii) social deprivation. However the actual numbers of people from BME communities having a stroke are not as high as would be expected as there are fewer older black and minority ethnic people in London.
  2. Overview of stroke pathway Timescale different for individual patients Underpinning themes Three main phases- transition through theme is a vital element we need to manage