Doxycycline are sensitive against
Many gram-positive and gram-negative bacteria.
Chlamydiae and spirochetes.
Doxycyline is the drug of choice in infaction caused
Rickettsiae Rocky mountain spotted
fever and rickettsial pox.
Chlamydia Trachoma and peittacosis.
Bacillus anthracis Anthrax.
Spirochetes Lyme’s disease.
Doxycycline use in a regimen for
treatment of gastic ulcer caused by
Also with amino glycoside for plague,
tularemia and brocellosis
A. Gastrointestinal adverse effects
Nausea vomiting and diarrhea.
B. Bony structures and teeth
During pregnancy it can deposited in fetal
teeth leading to fluorescence ,discoloration
and enamel dysplasia.
C. Liver toxicity
Hepatic toxicity leading to hepatic
E. Local tissue