Human Genome Project

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Human Genome Project

  1. 1. Human Genome Project
  2. 2. Human Genome Project
  3. 3. Stated Goals of HGP <ul><li>identify all the approximately 20,000-25,000 genes in human DNA, </li></ul><ul><li>determine the sequences of the 3 billion chemical base pairs that make up human DNA, </li></ul><ul><li>store this information in databases, </li></ul><ul><li>improve tools for data analysis, </li></ul><ul><li>transfer related technologies to the private sector, and </li></ul><ul><li>address the ethical, legal, and social issues (ELSI) that may arise from the project. </li></ul>
  4. 4. Ethical, Legal and Social Issues <ul><li>Fairness in the use of genetic information </li></ul><ul><li>Privacy and confidentiality </li></ul><ul><li>Psychological impact and stigmatization </li></ul><ul><li>Reproductive issues </li></ul><ul><li>Clinical issues </li></ul><ul><li>Conceptual and philosophical implications </li></ul><ul><li>Health and environmental issues </li></ul><ul><li>Commercialization of products </li></ul>
  5. 5. Conceptual and philosophical implications <ul><li>Do people's genes make them behave in a particular way? </li></ul><ul><li>Can people always control their behavior? </li></ul><ul><li>What is considered acceptable diversity? </li></ul><ul><li>Where is the line between medical treatment and enhancement? </li></ul>
  6. 6. Human Monogamy Gene
  7. 7. Voles and Behavior <ul><li>Prarie Voles and Montane Voles </li></ul><ul><li>Pair Bonding and the brain </li></ul><ul><li>Genetic component </li></ul>
  8. 8. Vasopressin in the Vole Brain  Prairie Montane
  9. 9. Researchers Say: <ul><li>&quot;influence of AVP on pair-bonding in voles may be of relevance also for humans,&quot; although the &quot;relatively small effect size ... clearly does not mean that this polymorphism may serve as a predictor of human pair-bonding on the individual level.“ </li></ul><ul><li>&quot;it's possible to have the gene variant but not have the marital difficulties,&quot; and vice versa. &quot;Human relationships are so complicated,&quot; Parens is paraphrased as saying, &quot;that the effect of any one gene would be very small .&quot; </li></ul>
  10. 10. The Popular Media Says: <ul><li>&quot;Whether a man has one type of gene versus another could help decide whether he's good 'husband material,'&quot; announces HealthDay News . </li></ul><ul><li>&quot;Marriage problems? Husband's genes may be to blame,&quot; says a Reuters headline writer. </li></ul><ul><li>&quot;Marital woes can often be attributed to men's genetic make-up,&quot; declares Agence-France Press . </li></ul><ul><li>&quot;What if you could tell whether a man is husband material just by peering at his genes?&quot; wonders  New Scientist . </li></ul>
  11. 11. Speculation on the “Divorce Gene” <ul><li>&quot;raises the highly speculative possibility that scientists could one day develop drugs to target the gene in an attempt to prevent marriages from falling apart.“ </li></ul><ul><li>Telegraph </li></ul>

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