Antisocial Personality Disorder (ASPD) Katherine Casey San José State University
<ul><li>Emotional Learning Disorder </li></ul><ul><li>Empathy </li></ul><ul><li>Remorse </li></ul><ul><li>Violation of oth...
Behavioral Examples of Persons with ASPD <ul><li>Aggression </li></ul><ul><li>Stealing </li></ul><ul><li>Lying </li></ul><...
Diagnosis of ASPD: DSM-IV <ul><li>Conduct disorder as a child </li></ul>
Biological Perspective <ul><ul><li>Genetically inherited: Twin studies </li></ul></ul><ul><ul><li>Low levels of activity i...
Psychoanalyst Perspective <ul><li>Influence of abusive or absent parents </li></ul><ul><li>Child feels rejected </li></ul>...
Behaviorist Perspective <ul><li>Parents reward, or fail to punish, child's antisocial behaviors  </li></ul><ul><li>Reinfor...
Prevalence Rates <ul><ul><li>Men: 3% </li></ul></ul><ul><ul><li>Women: 1% </li></ul></ul>
Biological Perspective <ul><li>Lower brain activity in the amygdala and orbitofrontal cortex (OFC). </li></ul>
Amygdala <ul><li>Charles Whitman killed 17 people and wounded 31 </li></ul><ul><li>Walnut-sized tumor in his right amygdal...
Schneider et al. (2000).‏ <ul><li>Which brain regions contribute to ASPD? </li></ul><ul><li>Differential aversive classica...
Results <ul><li>Persons with ASPD had opposite response patterns in the amygdala and prefrontal cortex when compared to co...
Anderson, Bechara, Damasio, Tranel, and Damasio (1999). <ul><li>Social and moral functioning of early-onset (EO) prefronta...
Results <ul><li>EO participants demonstrated more severe and impulsive antisocial behaviors than AO participants. </li></u...
Blair et al. (2006). <ul><li>Which specific prefrontal cortex regions are impaired in persons with ASPD? </li></ul><ul><li...
Results <ul><li>Persons with ASPD had significantly more  </li></ul><ul><li>errors on the OFC task. </li></ul>
Conclusion <ul><li>Emotional learning disorder involves dysfunctions in the amygdala and OFC as well as sociocultural fact...
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The dynamics of Antisocial Personality Disorder, commonly known in its extreme form as Psychopathy.

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ASPD presentation

  1. 1. Antisocial Personality Disorder (ASPD) Katherine Casey San José State University
  2. 2. <ul><li>Emotional Learning Disorder </li></ul><ul><li>Empathy </li></ul><ul><li>Remorse </li></ul><ul><li>Violation of others’ rights </li></ul>
  3. 3. Behavioral Examples of Persons with ASPD <ul><li>Aggression </li></ul><ul><li>Stealing </li></ul><ul><li>Lying </li></ul><ul><li>Conning </li></ul><ul><li>Impulsivity </li></ul><ul><li>Inability to plan for the future </li></ul>
  4. 4. Diagnosis of ASPD: DSM-IV <ul><li>Conduct disorder as a child </li></ul>
  5. 5. Biological Perspective <ul><ul><li>Genetically inherited: Twin studies </li></ul></ul><ul><ul><li>Low levels of activity in certain brain regions </li></ul></ul><ul><ul><li>Less prefrontal gray matter </li></ul></ul>
  6. 6. Psychoanalyst Perspective <ul><li>Influence of abusive or absent parents </li></ul><ul><li>Child feels rejected </li></ul><ul><li>Lack of emotional ties </li></ul><ul><li>Child fails to develop an adequate superego (conscience) </li></ul>
  7. 7. Behaviorist Perspective <ul><li>Parents reward, or fail to punish, child's antisocial behaviors </li></ul><ul><li>Reinforcement of behaviors such as lying, stealing, and aggression </li></ul>
  8. 8. Prevalence Rates <ul><ul><li>Men: 3% </li></ul></ul><ul><ul><li>Women: 1% </li></ul></ul>
  9. 9. Biological Perspective <ul><li>Lower brain activity in the amygdala and orbitofrontal cortex (OFC). </li></ul>
  10. 10. Amygdala <ul><li>Charles Whitman killed 17 people and wounded 31 </li></ul><ul><li>Walnut-sized tumor in his right amygdala </li></ul><ul><li>Early evidence of amygdala's role in regulation of antisocial behaviors </li></ul>
  11. 11. Schneider et al. (2000).‏ <ul><li>Which brain regions contribute to ASPD? </li></ul><ul><li>Differential aversive classical conditioning and fMRI </li></ul><ul><li>12 people with ASPD and 12 controls </li></ul><ul><li>Measured the degree to which a negative affect toward CS+ developed </li></ul>
  12. 12. Results <ul><li>Persons with ASPD had opposite response patterns in the amygdala and prefrontal cortex when compared to controls. </li></ul><ul><li>Information arrived in the prefrontal cortex at slower rates than those of controls, which delayed emotional learning. </li></ul>
  13. 13. Anderson, Bechara, Damasio, Tranel, and Damasio (1999). <ul><li>Social and moral functioning of early-onset (EO) prefrontal damage and adult-onset (AO) damage </li></ul><ul><li>2 early-onset participants </li></ul><ul><li>25 adult-onset participants </li></ul><ul><li>MRI, four tasks of social and moral knowledge, and behavioral histories </li></ul>
  14. 14. Results <ul><li>EO participants demonstrated more severe and impulsive antisocial behaviors than AO participants. </li></ul><ul><li>No evidence that EO participants had acquired complex social and moral knowledge </li></ul>
  15. 15. Blair et al. (2006). <ul><li>Which specific prefrontal cortex regions are impaired in persons with ASPD? </li></ul><ul><li>25 participants with ASPD </li></ul><ul><li>30 controls </li></ul><ul><li>3 measures which had shown specific activation of 3 prefrontal subregions </li></ul>
  16. 16. Results <ul><li>Persons with ASPD had significantly more </li></ul><ul><li>errors on the OFC task. </li></ul>
  17. 17. Conclusion <ul><li>Emotional learning disorder involves dysfunctions in the amygdala and OFC as well as sociocultural factors </li></ul><ul><li>ASPD has serious social implications </li></ul><ul><li>There is no known effective treatment </li></ul>

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