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IESE - MBA Healthcare Club - Welcome to the Future of Medicine (10 mar 2015)


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A brief summary of the Future of Medicine in 15 trends.

Published in: Healthcare

IESE - MBA Healthcare Club - Welcome to the Future of Medicine (10 mar 2015)

  1. 1. THE FUTURE OF MEDICINE: We are the last generation to know so little about our health Barcelona, 10 de Marzo de 2015
  2. 2. Director E-Health Innovation Department @HSJDBCN Jorge Juan FERNÁNDEZ @jorgejuan Director MOEBIO / d·HEALTH @moebiobarcelona
  3. 3. Generations do differ, but less because people differ than because opportunities do. Clay Shirky was right… “Cognitive Surplus” (2010)
  6. 6. The Second Age Machine The 1st Machine Revolution was about augmenting physical power. The 2nd Machine Revolution will be about augmenting mental power. SOURCE: “The Second Machine Age”, Erik Brynjolfsson and Andrew McAfee (2014)
  7. 7. MEDICINE is becoming an information technology SOURCE: Kairos Future, 2013 1850 1950 2000 Hygiene revolution Pharma revolution Data revolution If data is the currency of the new system, trust is the central bank.
  9. 9. It is very important to know “what is coming”
  10. 10. What is happening in the industry/market? Smartphone = PlatformEmpowered Patients Synthetic Biology Portable Diagnostics 3D printingOnline care Big Data Precision Medicine Hacking Life’s Code Artificial Intelligence Sensors Medical Tricoder Human augmentation Fighting AgingBrain Computer Interface
  11. 11.
  12. 12. Virtual visits on the rise: Telemedicine will expand healthcare into our homes and beyond #1
  13. 13. Within the Kaiser Permanente Northern California system, the number of virtual physician visits grew from 4.1 million in 2008 to 10.5 million in 2013 SOURCE: These trends suggest dramatically increasing comfort among both patients and physicians with health care provided virtually
  14. 14. Touchpoints in Patient Experience are mainly digital
  15. 15. Telepresence robots: Allowing top physicians to beam into locations around the world for consultation and rounds at the hospital
  16. 16. Patient-to-Patient interactions will strongly outpace Provider-to-Patient interactions #2
  17. 17. Citizens are becoming the CEOs of their own health Smart Patients is an online community where patients and caregivers learn from each other about treatments, clinical trials, the latest science, and how it all fits into the context of their experience. Crohnology is a Patient-Powered Research Network, currently focused on Crohn's & Colitis that allows any patient to contribute to research for the cure.
  18. 18. SOURCE: The closest we have to a Michelin Guide… At CureTogether, 2,826 people who experience Acid Reflux came together to rate 39 treatments.
  19. 19. SOURCE: Not only information, also product innovation
  20. 20. The smartphone is the healthcare platform of today and the future #3
  21. 21. / InShape Moms A B C D Cell phones becoming the health platform of today & future The center of gravity of the Internet is shifting: from fixed access (computers) to ubiquitous access (smartphones & tablets)
  22. 22. Digital Therapies: EU reimbursed apps
  23. 23. Prescribing more than medicine: Apps & Peripherals (Apps & Adds) Themometer (Kinsa Smart) GeckoCap: improving medication adherence in pediatric asthma NETRA (MIT) Peek Vision iBGStar
  24. 24. Nurses-in-an-iPhone (49,95$ a month)
  25. 25. DermatologistOnCall ($59 virtual visits) SOURCE: DermatologistOnCall® A virtual health solution that makes accessibility to a board-certified dermatologist easier, faster and more convenient than ever.
  26. 26. FirstDerm ($40 virtual visits) SOURCE: FirstDerm. Your online Dermatologist. Send a picture of your skin concern anonymously and receive an answer from a board certified dermatologist in under 24 hours.
  27. 27. Printing Pixels: Before the 3D Printing (hardware) comes the 3D Modeling (software) #4
  28. 28. 3D Printing works with any material (glass, titanium,…) and any scale (micro scale, building scale,…)
  29. 29. 3D Printing: Medicine #1 area of application  Tissues with blood vessels  Low–Cost Prosthetic Parts  Drugs  Tailor–made sensors  Tumor Models  Bone  Heart Valve  Ear cartilage  Medical equipment  Cranium Replacement  Synthetic skin  Organs WARNING: 3D printing will cause an intellectual property nightmare. 10x worse than what we’re seeing with digital files. 12 Things We Can 3D Print in Medicine Now
  30. 30. 3D Printing at HSJD
  31. 31. 3D Electronics Printing
  32. 32. Bioprinting: instead of using ink, using cells When we can regrow a heart, liver, lung or kidney when we need it instead of waiting for the donor to die.
  33. 33. The Medical Tricorder: from Medical Devices to Consumer Devices The most disruptive thing in the market is not technology, but rather the customer #5
  34. 34. The Robot Will See You Now
  35. 35. A different type of future…
  36. 36. $10M Qualcomm Tricorder XPRIZE
  37. 37. The Medical Tri-Corder: consumers are in charge (from B2B to B2C) In the near future, we’ll be able to do a lot of basic health care for ourselves.
  38. 38. SCANADU: Check your health as easily as your email
  39. 39. SCANADU: First release
  40. 40. TYTO: Conducting a physical examination from the comfort of your home! SOURCE:
  41. 41. Portable Diagnostics: Devices that are becoming our go-to diagnostic centers #6
  42. 42. Portable Diagnostics DISEASE DECODED Imagine a simple blood test that can tell you, at the molecular level, the exact type of disease you have and its severity before presenting any symptoms. Imagine using the same test to monitor the success of the treatment. By January 2013, Kahol’s team had incorporated 33 diagnostic tests, including for HIV, syphilis, pulse oximetry, and troponin (relating to heart attack) into the Swasthya Slate and reduced its cost to $800 per unit. In high volumes, the Swasthya Slate can be produced for as little as $150 per unit.
  43. 43. Portable Diagnostics
  44. 44. Doctors or Algorithms? Healthcare will move from “Human-to- Human” to “Machine-to-Human” #7
  45. 45. Watson? The new Deep Blue (chess, Kasparov, 1997)
  46. 46. Dr. Watson: a new Doc in town “In the next 10 years, data science and software will do more for medicine than all of the biological sciences together” “IBM Watson can go through literature the same way we do now in two weeks, and do that in two seconds”
  47. 47. “80% of what doctors do today will be replaced by technology in 10 years” (Vinod Khosla)
  48. 48. Some interesting results After only one year, Watson’s successful diagnostic rate for lung cancer is 90%, compared to 50% for human doctors. One such Watson system contains 40 million documents, ingests an average of 27.000 new documents per day, and provides insights for thousands of users.
  49. 49. A number of scientists are concerned: “artificial intelligence could end mankind”
  50. 50. Big Data in Healthcare: Big data growth is accelerating as more of the world’s activity is expressed digitally #8
  51. 51. Healthcare is one of the most intensive sectors in knowledge, which comes from the scientific publications, and in data obtained from the patients’ real information KNOWLEDGE BIOMEDICAL LITERATURE:  Medical information is doubling every 5 years.  PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books.  More than 700.000 added each year.  6-12 months: publishing the latest medical research information can be delayed up to one year.  15 years: the time it can take for the latest evidence to be put into practice.
  52. 52. Healthcare is one of the most intensive sectors in knowledge, which comes from the scientific publications, and in data obtained from the patients’ real information DATA Clinical Data Biomedical Imaging ‘Omics & Systems Biology Biometric Data Medical devices mHealth / Apps Social Media Online communities Environment  By 2011, U.S. healthcare organizations had generated 150 exabytes -- that's 150 billion gigabytes -- of data.  Kaiser Permanente alone might have as much as 44 petabytes of patient data just from its electronic health record (EHR) system, or 4,400 times the amount of information held at the Library of Congress. Source: IHT2 consultancy
  53. 53. Humans can’t compete with computers
  54. 54. The 4 Vs of Big Data VOLUME Scale of data 90% of the data in the world today was created within the last two years 5x more data being created than stored Global size of data in healthcare estimated in 2011 to be 150 Exabytes VARIETY Different forms & sources of data VELOCITY Analysis of streaming data VERACITY Uncertainty of data People-to-People (Social Media, online communities) People-to-Machine (computers, mobile, medical devices) Machine-to-Machine (sensors, GPS, barcode scanners) 136M emails sent every minute 306 hours of YouTube video uploaded every minute 433.000 tweets per minute 1 in 3 business leaders don’t trust the information they use to make decisions
  55. 55. Big Data & Advanced Analytics: The 7 trillion piece puzzle DNA / RNA Proteins Metabolites Cells / Tissues 25.000 genes 100.000 proteins 2.400 compounds 7 trillion human cells Organs 9 organ- systems 29 organs Body Society 4 basic types of tissues 1 human body 7 billion people SOURCE: Siemens AG 2012
  56. 56. HCE Información clínica de asistencia especializada Genética Información genética (full exome) Internet of Things Medical devicesInformación clínica de asistencia primaria Apps Brain Data Texto eCAP ????? SIRE Receta electrónica Data Data Cuestionarios web Redes Sociales Comunidades online Big Data: Volumen, Variedad, Velocidad 10 11 12 Adherencia terapéutica 1 2 3 4 5 6 7 8 9 ASÍNCRONO REAL-TIME Data Texto Data Texto Texto Texto Data
  57. 57. Data will transform… Medicine (as a Science) Healthcare (as an Industry) Care delivery (as a Service) #1 #2 #3
  58. 58. Precision Medicine: Discovering unique therapies that treat an individual’s condition based on the specific abnormalities of their disease #9
  59. 59. Precision Medicine
  60. 60. Human augmentation & Exoskeletons #10
  61. 61. Amputees can now control limbs with their thoughts
  62. 62. Human Augmentation
  63. 63. Exoskeletons
  64. 64. Brain Computer Interface (BCI): Technology will help us understand the brain (the last human frontier) #11
  65. 65. These discoveries and cutting-edge tools will allow us to access brain information in noninvasive ways, opening up new spectrums of science and human understanding
  66. 66. OpenBCI We are a community of researchers, engineers, artists, scientists, designers, makers, and more. The one thing we all have in common? We share an unfaltering passion for harnessing the electrical signals of the human brain and body to further understand and expand who we are.
  67. 67. MUSE: improve your mental fitness, no gym membership required
  68. 68. MUSE: improve your mental fitness, no gym membership required
  69. 69. The Human Brain: the last frontier
  70. 70. Large-scale Brain Mapping projects: US (apr 2013) vs EU (nov 2013) Dr. Henry Markram’s Human Brain Project recently got 1 billion worth of funding from the European Union. The money will be spread in 100 million dollar payments over the next 10 years and is aimed at scaling up Markram’s past research in simulating parts of a rat brain to the first and most comprehensive attempt to reverse-engineer and simulate the complete human brain. 112 Partners in 24 countries in Europe and around the world BRAIN Initiative (Brain Research through Advancing Innovative Neurotechnologies)
  71. 71. Web 3.0 (The Sensors’ Web): From Wearables to Insideables and the human body as the next computer interface #12
  72. 72. WEARABLES everywhere…
  73. 73. Almost 40% of the 153 “Internet of Things” deals in 2013 raising $1 billion from VC were healthcare businesses (ranging from ingestible sensors to smartphone-enabled devices) SOURCE:
  74. 74. WEARABLE SENSORS: Google + Novartis: developing a smart contact lens that can monitor the wearer’s blood sugar level for diabetic patients
  75. 75. WEARABLE SENSORS: SENSIMED Triggerfish
  76. 76. You are the interface: The screen is out and the skin is IN The human body is the next computer interface New 'electronic skin' patches monitor health wirelessly
  77. 77. IMPLANTABLE SENSORS: Implants will enhance, or in some cases, replace exoskeletons
  78. 78. INSIDEABLES: The Next Sensor Will Be IN You Proteus's focus is about getting people to take their medication as prescribed Tech is moving from the outside to the inside of our bodies
  79. 79. Synthetic Biology The creation of living systems from non- living chemicals designed on a computer #13
  80. 80. Reprogramming life
  81. 81. Reprogramming life (2010)
  82. 82. MIT iGem Competition
  83. 83. Hacking Life’s Code #14
  84. 84. Hacking Life’s Code
  85. 85. Hacking Life’s Code In both graphs, note the sudden and profound out-pacing of Moore's Law beginning in January 2008. This represents the time when the sequencing centers transitioned from Sanger-based (dideoxy chain termination sequencing) to 'second generation' (or 'next-generation') DNA sequencing technologies.
  86. 86. Sequencing and mapping will lead to our greatest advancements
  87. 87. Do you really want to know YOUR future?
  88. 88. Fighting aging Some of the greatest minds are exploring ways to end death #15
  89. 89. Making 100 Years Old the “New 60”
  90. 90. The Palo Alto Longevity Prize (1M $)
  91. 91. Can a COMPANY solve death? Google Ventures: 36% of $2 Billion invested in healthcare companies that will slow aging, reverse disease, and extend life
  92. 92. Companies fighting aging CALICO (California Life Company) Human Longevity Inc. (HLI)
  93. 93. Experts are not reaching a consensus 120 Aging is not equivalent to the aberrant process of Alzheimer’s disease; it is in fact a distinctly different neurological process.
  94. 94. No stakeholder of healthcare is ready for what is coming. In 10 years, you will trust your computer more than your doctor. AI in Medicine will enable better dianoses and personalized medical recommendations. Technology might change us more in a generation than evolution has done over million of years. We are moving from “evolution by natural selection” to “evolution by intelligent decision”. It’s not “Human Touch” OR “Technology” but AND. #1 #2 #3 #4 #5 #6
  97. 97. CONCLUSION: A tornado more than a tsunami