CHARITE ENTREPRENEURSHIP SUMMIT 2016 - Collaborative Innovation in Health Care & Life Sciences (28 may 2016)

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A brief overview of COLLABORATIVE INNOVATION in Health Care and Life Sciences

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CHARITE ENTREPRENEURSHIP SUMMIT 2016 - Collaborative Innovation in Health Care & Life Sciences (28 may 2016)

  1. 1. Collaborative Innovation in Health Care and Life Sciences Bringing new minds, skills and collaborations to problems in HC & LS Jorge Juan FERNÁNDEZ GARCÍA (@jorgejuan) Berlin, 27 May 2016
  2. 2. What is COLLABORATIVE INNOVATION? COLLABORATIVE INNOVATION: It’s a different type of innovation, characterized by:  Unique partnerships, fostering innovation through collaboration, rather than competition  Involving many agents (not just bilateral agreements), traditionally separated  More concerned about “creating value” than about “capturing value” Hospitals Academia Industry Governments IndividualsResearch institutions
  3. 3. CROWDSOURCING CHALLENGES & COMPETITIONS Kaggle and InnoCentive https://www.kaggle.com https://www.innocentive.com  Founded in 2010  >450.000 data scientists  202 competitions completed  12 still active  Many pertaining to HC&LS  Formed in 2001 (as pharma companies begun to struggle with their pipelines)  Spun out from Eli Lilly  >375.000 problema solvers  >2.000 open challenges held
  4. 4. HACKATHONS: Hacking Medicine vs Hacking Health Designed to bring experts from different disciplines face to face http://hackingmedicine.mit.edu/ http://hackinghealth.ca/  Founded in 2011  Headquarters: MIT (Boston, US)  Our Mission: Hack clever solutions for healthcare. Break it down, build it up, make it better around the world.  Founded in 2012  Headquarters: Montreal (Canada)  Our mission: Foster innovative digital health ecosystems. Engage and inspire its stakeholders. Support the development of human-centric solutions.
  5. 5. OPEN INNOVATION (through challenges) UK – Longitude Prize Longitude Prize is a challenge with a £10 million prize fund to help solve the problem of global antibiotic resistance. It is being run by Nesta and supported by Innovate UK as funding partner. https://longitudeprize.org/
  6. 6. OPEN INNOVATION (through challenges) HBS – Precision Trials Challenge The Precision Trials Challenge is a pioneering competition to generate ideas on how to bring diagnostics and therapies to market faster by reinventing the clinical trials process. www.precisiontrialschallenge.org
  7. 7. OPEN INNOVATION (through challenges) Ideas Challenge – Harvard Medical School  But in February 2010, Drew Faust, president of Harvard University, sent an email invitation to all faculty, staff and students at the university (more than 40,000 individuals) encouraging them to participate in an “ideas challenge” that Harvard Medical School had launched to generate research topics in Type 1 diabetes.  Eventually, the challenge was shared with more than 250,000 invitees, resulting in 150 research ideas and hypotheses.  These were narrowed down to 12 winners, and multidisciplinary research teams were formed to submit proposals on them.  Today, seven teams of multidisciplinary researchers are working on the resulting potential breakthrough ideas. http://sloanreview.mit.edu/article/experiments-in-open-innovation-at-harvard-medical-school/ https://hms.harvard.edu/news/harvard-medicine/ideation-challenge-diabetes
  8. 8. HOSPITALS Hospitals getting together http://www.ichom.org/ The International Consortium for Health Outcomes Measurement (ICHOM) is a non-profit organization founded by three esteemed institutions with the purpose to transform health care systems worldwide by measuring and reporting patient outcomes in a standardized way. Goals of HVHC are to:  (A) improve care, improve health, and reduce costs by  (B) identifying and accelerating widespread adoption of best-practice care models and innovative value- based payment model. http://highvaluehealthcare.org
  9. 9. HOSPITALS 100+ children’s hospitals in the US http://www.solutionsforpatientsafety.org “The work we do is not really about collecting data or creating processes – it’s about saving kids’ lives, each and every day…”. - Dr. Steve Muething (Cincinnati Children's Hospital), SPS co-leader
  10. 10. RESEARCH INSTITUTIONS BIST – Barcelona Institute of Science and Technology Getting together not to reach scale, but to change scope
  11. 11. COMPANIES Health Transformation Alliance (HTA) http://www.htahealth.com/ The current health care system is unsustainable and it costs too much. The Health Transformation Alliance’s goal is to improve the way corporations provide health care benefits in an effort to create better health care outcomes for their employees. By coming together to share expertise, 20 of America’s largest corporations seek to make the current multilayered supply chain more efficient. We view it as A Better Way. Collectively, the 20 companies are responsible for health care benefits for four million people and spend more than $14 billion annually on health care for employees, their dependents and retirees. 1. American Express Company 2. American Water 3. BNSF Railway Company 4. Brunswick Corporation 5. Caterpillar Inc. 6. The Coca-Cola Company 7. E.I. du Pont de Nemours & Company 8. HCA Inc. 9. The Hartford Financial Services Group Inc. 10. IBM Corporation 11. Ingersoll Rand 12. International Paper Company 13. Lincoln Financial Group 14. Macy’s Inc. 15. Marriott International Inc. 16. NextEra Energy Inc. 17. Pitney Bowes Inc. 18. Shell Oil Company 19. Verizon Communications Inc. 20. Weyerhaeuser Company
  12. 12. REGIONS Massachusetts Life Sciences Center (MLSC) - Boston (US) http://www.masslifesciences.com A 10-year, $1 billion initiative to invest in the state’s life sciences sectors, enacted by the Massachusetts legislature in June 2008. The Initiative is administered by the Massachusetts Life Sciences Center (MLSC), which serves as the “hub” of the state’s life sciences community.
  13. 13. COUNTRIES EIT Health (6 Co-Locations Centers) https://eithealth.eu/ EIT Health has formed six Co- location Centres across Europe, with Headquarters based in Munich:  London (UK/Ireland)  Stockholm (Scandinavia)  Barcelona (Spain)  Paris (France)  Heidelberg (Germany)  Rotterdam (Belgium-Netherlands) EIT Health furthermore includes 92 associate partners and 6 “InnoStars” regions in Wales, Portugal, Poland, Hungary, Slovenia and Croatia. EIT Health develops talents, drives innovative business ideas forward and boosts the global competitiveness of European industry through three key programs that will offer a vibrant ecosystem for future entrepreneurs, academics and businesses.
  14. 14. CENTERS FOR THERAPEUTIC INNOVATION (CTI) - PFIZER Launched in 2010, Pfizer’s Centers for Therapeutic Innovation (CTI) is a unique model for academic-industry collaboration, designed to bridge the gap between early scientific discovery and its translation into new medicines. https://www.pfizercti.com/
  15. 15. GLOBAL PHARMACEUTICAL FIRMS + WORLD-LEADING UNIVERSITIES Apollo Therapeutics http://www.apollotherapeutics.com/
  16. 16. PLATFORMS Project Data Sphere https://www.projectdatasphere.org The Project Data Sphere platform is available to researchers affiliated with life science companies, hospitals and institutions, as well as independent researchers. Anyone interested in cancer research can apply to become an authorized user. The Project Data Sphere initiative can help the cancer community unlock the potential of valuable data by generating new insights and opening up a new world of research possibilities.
  17. 17. Bio-X Stanford University (US) https://biox.stanford.edu/  Launched in 1998.  Nearly 700 Bio-X affiliated scholars who span the campus and come together at the Clark Center. Bio-X is Stanford's pioneering interdisciplinary biosciences institute, bringing together biomedical and life science researchers, clinicians, engineers, physicists, and computational scientists to unlock the secrets of the human body. MEDICINE + BASIC SCIENCES + ENGINEERING
  18. 18. SPARK Stanford University (US) http://med.stanford.edu/sparkmed.html SPARK is a partnership between university and industry dedicated to:  Educating faculty, fellows, graduate students and medical students on the discovery and development process for therapeutics and diagnostics.  Advancing promising research discoveries to the clinic and commercial sector.  Innovating efficient and cost-effective approaches to drug discovery and development. Required reading for any scientists in academia who plan to accelerate the translation of university-based discoveries into clinically relevant drugs and diagnostics and into the clinic.
  19. 19. BioMedX Heidelberg (Germany) http://bio.mx/ The BioMed X Innovation Center is an exciting new collaboration model at the interface between academia and industry. Each team is typically sponsored by a corporate pharmaceutical or biotech partner of BioMed X. At the end of a fully funded project term, successful projects are either internalized into the development pipeline of the respective pharmaceutical or biotech sponsor or spun off into an independent startup company. “An OUTCUBATOR: bringing researchers with varied expertise and skills together in one physical location can accelerate research”.
  20. 20. Biodesign Stanford University http://biodesign.stanford.edu/ A systematic approach to needs finding and the invention and implementation of new biomedical technologies. IRELAND STOCKHOLM BARCELONA AARHUS
  21. 21. SYNTHESIS - Policy prescriptions “Choose wisely when to compete, and when to collaborate” Soon “collaborative advantage” will win over “competitive advantage” GOVERNMENTS COMPANIES INDIVIDUALS  Its role has changed:  BEFORE: spend a good portion of their budgets on the right priorities  NOW: involve the private sector with matching funds; align all the different governmental levels; change the HC payment system to create the right incentives.  Everything starts with “talking to the right person at the right time”  Choose your “large-scale problem”: safety, cancer, etc.  Develop new skills (a must for physicians and researchers)  Engage and create a network of “people with different backgrounds from yours”
  22. 22. Director E-Health Innovation Department jfernandez@hsjdbcn.org @HSJDBCN Jorge Juan FERNÁNDEZ @jorgejuan Director MOEBIO / d·HEALTH jjfernandez@biocat.cat @moebiobarcelona

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