Trypanosoma
brucei

•  Trypanosoma
brucei
is
a
parasite
in
Kingdom


   
Pro0sta

•  Can
be
divided
into
two
subspecies:

...
Rubella
Virus

•  Included
in
the
virus
family
Togaviridae

•  Single‐stranded
RNA
with
a
polyhedral
capsid,


   
surroun...
Sarcoptes
scabiei

•  Kingdom:
Animalia
Parasi0c

   Arthropod


•  This
microscopic
eight
legged
mite

   causes
the
skin...
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Mo W 15

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Mo W 15

  1. 1. Trypanosoma
brucei
 •  Trypanosoma
brucei
is
a
parasite
in
Kingdom

 
Pro0sta
 •  Can
be
divided
into
two
subspecies:

 
T.
brucei
qambiense
and
T.
brucei
rhodesiense
 Photo Credit: http:// www.pnas.org/content/100/3/ •  Organisms
are
slender
with
a
wavy
membrane,

 F1.medium.gif 
protruding
flagellum,
and
visible
nucleus
 •  Causes
disease
“African
Sleeping
Sickness”

 •  TransmiEed
to
humans
through
the
Tsetse
Fly
(only
found
in
 Africa)
and
infects
the
blood
~
70,000
cases
per
year,
larger
 epidemics
occur
 •  Symptoms
include
fever,
enlarged
spleen,
swollen
lymph
 nodes,
joint
pains,
and
more
serious
problems
such
as
sleep
 disorders,
coma,
and
death
 •  Treatment
includes
Suramin
and
Melarsoprol

  2. 2. Rubella
Virus
 •  Included
in
the
virus
family
Togaviridae
 •  Single‐stranded
RNA
with
a
polyhedral
capsid,

 
surrounded
by
a
lipoprotein
envelope
 Photo Credit: http:// www.mayoclinic.com/health/ •  Symptoms
of
Rubella
Virus
last
2‐3
days
 medical/IM01794 •  Symptoms
include
slight
fever
(102
degrees
F),
inflamed,
red
 eyes,
rash
that
spreads
over
the
body,
headachesThere
is
no
 treatment
for
Rubella
Virus
 •  Rubella
Virus
must
run
its
course
throughout
the
body
 •  Most
children
are
given
the
vaccine
(MMR‐
measles‐mumps‐ rubella)
in
two
doses
within
their
childhood
years
 –  Fewer
than
300
cases
per
year,
periodic
outbreaks

  3. 3. Sarcoptes
scabiei
 •  Kingdom:
Animalia
Parasi0c
 Arthropod

 •  This
microscopic
eight
legged
mite
 causes
the
skin
disease
Sarcop0c
 mange
(scabies).
 •  Symptoms:
severe
itching
especially
 depts.washington.edu at
night,
red
blisters,
and
red
 irregular
burrow
tracks.
 •  Es0mated
1
million
cases
in
US
 annually
(old
sta0s0cs)
 •  Highly
contagious,
can
be
caught
 from
physical
contact
with
someone
 infected,
a
domes0cated/wild
 animal
infected,
and
fields.
 Treatment:
Lo0ons
and
oral
 medica0ons
 nationaalhuidcentrum.nl

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