2. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
HISTORY:
•
In addition to the deformity
evident in the clinical photo, this animal
was lame and showed pain and
warmth on palpation of the lower limb.
3. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
LESION/S AND DESCRIPTION
• calcification
• Hemorrhage
• Metaphyseal enlargement
4. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Basic disease process/es
• Inflammation
• Necrosis
5. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
DIAGNOSIS
• Hypertrophic osteodystrphy
8. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
BASIS/ BASES FOR THE DIAGNOSIS
• History
o Animal
o Breed
o Age
o Specimen
9. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Differential diagnosis and the reasons for
such.
• Panosteitis
It is a self-limiting developmental
disease of young, large and giant breeds
of dogs resulting in pain, lameness in one
or more limbs.
10. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
• Hypertrophic Osteopathy (HO)
It is a condition that affects long
bones but is secondary to a primary
thoracic or abdominal mass. The bony
lesions are characterized by bilateral,
symmetrical swellings affecting the distal
extremities of the four limbs.
11. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
• Etiological information
The cause of HOD is currently
unknown
12. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Methods of transmission of the etiology
and spread
Genetic component is suspected.
13. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Other lesions present in the other organs
not shown in the picture
metastatic calcification of the
aorta, endocardium, lungs, and kidneys
at necropsy.
14. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Other lesions present in the other organs
not shown in the picture
metastatic calcification of the
aorta, endocardium, lungs, and kidneys
at necropsy.
15. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Clinical signs
• Anorexia
• Depression
• pyrexia
• weight loss.
16. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Clinical signs
• Anorexia
• Depression
• pyrexia
• weight loss.
18. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Cause/s of death not necessarily
euthanasia
• Cardiac failure
• Respiratory failure
• Dehydration
19. SPECIMEN: POST-MORTEM VIEW OF
THE SAGITALLY-SPLIT DISTAL RADIUS OF
A 3-MONTH OLD GREAT DANE
Cause/s of death not necessarily
euthanasia
• Cardiac failure
• Respiratory failure
• Dehydration
Editor's Notes
HOD and PANO are both associated with dysfunction in long bone development. There is significant inflammation, edema and bone pain that can progress to deformity and bone necrosis.
