Ph d class

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Ph d class

  1. 1. H.Pylori
  2. 2. Classification: Domain Bacteria Phylum proteobacteria Class Epsilonproteobacteria Order Campylobacterales Family Helicobacteriaceae Genus Helicobater
  3. 3. Classification: Helicobacteraceae: Genera: Helicobacter, Wolinella, Flexispira,S ulfurimonas, Thiomicrospira, and Thiovulum
  4. 4. Microbiology of H. pylori - Genome -Morphology -Cell envelope, and LPS -Growth requirements - Metabolism
  5. 5. CLINICAL ASPECTS OF H. PYLORI ASSOCIATED DISEASES • Acute and chronic gastritis -Acute gastritis -Chronic gastritis • Peptic ulcer disease -Gastric ulcers -Duodenal ulcers • Gastric MALT lymphoma • Atrophic gastritis, intestinal metaplasia, gastric cancer
  6. 6. Natural History of Helicobacter pylori Infection
  7. 7. Role of H. pylori Virulence Factors
  8. 8. cag A (“cytotoxin associated gene A”)
  9. 9. VacA (vacuolating cytotoxin A)
  10. 10. H.pyloriPathogenesis of
  11. 11. H.pyloriPathogenesis of

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