Serotonin Project

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Serotonin Project

  1. 1. SEROTONIN Brought to you by: Rizzle Mu ñ oz, Crysta Custodio, and Jasmin Saromo
  2. 2. SEROTONIN STRUCTURE Chemical Symbol: C 10 H 12 N 2 O
  3. 3. <ul><li>Serotonin is a neurotransmitter produced in the brain </li></ul><ul><li>Also known as 5- Hydroxytryptamine </li></ul><ul><li>Found in gastrointestinal tract and blood stream </li></ul><ul><li>Plays an important part in the biochemistry of depression, bipolar disorder, and anxiety </li></ul>WHAT IS SEROTONIN?
  4. 4. SEROTONIN: BIOLOGICALLY
  5. 5. <ul><li>Serotonin Controls: </li></ul><ul><li>Cardiovascular function </li></ul><ul><li>Muscle contraction </li></ul><ul><li>Endocrine regulation </li></ul><ul><li>Reaction to pain </li></ul><ul><li>Vomiting </li></ul><ul><li>Aggression </li></ul>BIOLOGICAL PURPOSE
  6. 6. <ul><li>Increased Levels: </li></ul><ul><li>Pulmonary vasoconstriction causes an acute or chronic pulmonary hypertension </li></ul><ul><li>Retroperitoneal fibrosis or Ormond's disease </li></ul><ul><li>Cardiac fibrosis </li></ul><ul><li>Decreased Levels: </li></ul><ul><li>Carbohydrate C ravings </li></ul><ul><li>More sensitive to pain </li></ul>BIOLOGICAL EFFECT
  7. 7. SEROTONIN: PSYCHOLOGICALLY
  8. 8. <ul><li>Serotonin Controls: </li></ul><ul><li>Sleep </li></ul><ul><li>Sensory perception </li></ul><ul><li>Mood (depression) </li></ul><ul><li>Appetite </li></ul><ul><li>Behavior (sexual and hallucinogenic ) </li></ul><ul><li>Memory and Learning </li></ul>PSYCHOLOGICAL PURPOSE
  9. 9. <ul><li>Increased Levels: </li></ul><ul><li>More restful sleep </li></ul><ul><li>Elevated moods </li></ul><ul><li>Decreased Levels: </li></ul><ul><li>Anxiety </li></ul><ul><li>Depression </li></ul><ul><li>T rouble d sleep patterns </li></ul>PSYCHOLOGICAL EFFECT
  10. 10. SEROTONIN: Medications
  11. 11. <ul><li>S elective Serotonin Reuptake Inhibitor (SSRI) </li></ul><ul><ul><li>Stops the absorption in the presynaptic cell , which then causes and increase in extracelluar Serotonin levels </li></ul></ul><ul><li>Anti Anxiety Medication </li></ul><ul><ul><li>Stops the reabsorption of serotonin by the body. Ergo, it is produced only when it is necessary </li></ul></ul>Low Serotonin Levels
  12. 12. <ul><li>High serotonin levels lead to Serotonin Syndrome </li></ul><ul><li>Caused by taking two different drugs that effect the serotonin levels in the body at the same time </li></ul><ul><li>There are no medications, but discontinuing the drugs may help lower the levels </li></ul><ul><li>May be asked to stay in the hospital for observations until the levels decrease </li></ul>High Serotonin Levels
  13. 13. <ul><li>http://www.3dchem.com/moremolecules.asp?ID=287&othername=5-HT </li></ul><ul><li>http://en. wikipedia .org/ wiki / Serotonin </li></ul><ul><li>http://serendip.brynmawr.edu/bb/neuro/neuro99/web1/Byrd.html </li></ul><ul><li>http://www.vitamins-supplements.org/hormones/serotonin.php </li></ul><ul><li>http://pages.prodigy.net/unohu/topics_sero. htm </li></ul><ul><li>http://www.enotalone.com/article/4119.html </li></ul><ul><li>http://en.wikipedia.org/wiki/Selective_serotonin_reuptake_inhibitor </li></ul><ul><li>http://www.americanchronicle.com/articles/39221 </li></ul><ul><li>http://en.wikipedia.org/wiki/Serotonin_syndrome </li></ul><ul><li>http://www.mayoclinic.com/health/serotonin-syndrome/DS00860/DSECTION=5 </li></ul>RESOURCES

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