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Lupus nephritis

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lupus nephritis is a autoimmune disease, commonly seen in adult and child and the medical or nursing care is also very important for this type of disease condition.

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Lupus nephritis

  1. 1. LUPUS NEPHRITIS PREPARED BY, JAGDISH SAMBAD MSC.NURSING NEPHROLOGY IKDRC-ITS CON
  2. 2. DEFINITION  Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematous, an autoimmune disease.  It is a type of glomerulonephritis in which the glomeruli become inflamed.  As the result of SLE the cause of glomerulonephritis is said to be secondary and has a different pattern and outcome from conditions with a primary cause originating in the kidney.
  3. 3. CLASSIFICATION
  4. 4. CAUSES OF LUPUS NEPHRITIS:- Genetic predisposition. Auto immune disease. Like, SLE
  5. 5. SIGN AND SYMPTOMS OF LUPUS NEPHRITIS:-  Fever  Edema  High blood pressure  Joint pain  Muscle pain  Malar rash  Foamy urine
  6. 6. PATHO-PHYSIOLOGY  Due to autoimmune disease  B cell activation  Formation of auto-reactive antibodies vs nuclear Ag  Ab/Ag complexes  Recruitment of polys and mononuclear cells  Renal damage  Lupus nephritis is occur.
  7. 7. DIGNOSTIC EVALUATION  Blood test  Urine analysis  X-ray  Scan of the kidneys  Kidney biopsy.
  8. 8. MEDICAL MANAGEMENT:-  Mycophenolate mofetil {MMF}  Intravenous cyclophosphamide with corticosteroids.
  9. 9. COMPLICATION:-  Kidney problem  Cardiac problem  Pregnancy complication.
  10. 10. THANK YOU…

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