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Doctor Joseph Kraft Interview Slides - Father of Insulin Assay

The Introduction Slides used in the Dr. Joseph Kraft Interview: https://www.youtube.com/watch?v=w0nV-_ddXoc

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• Chairman, Department of Clinical
Pathology and Nuclear Medicine
• Chairman, Department of Pathology
Pathologist & Director of Laboratories
• Private Practice of Pathology
• Consultant Pathologist
• Pathologist & Director of Laboratories
• Forensic Pathologist, Denver City &
County
• Assistant Professor, Department of
Pathology, Colorado
• Resident in Pathology, University of
Colorado Medical Center
• Captain, United States Army Medical
Corps
• Fellow:
o College of American Pathologists
o American Society of Clinical
Pathologists
o American College of Nuclear
Physicians
• 1972-1990
.
• 1962
.
• 1959-1961
• 1956-1959
• 1953-1959
• 1951-1953
.
• 1951-1953
.
• 1949-1951
.
• 1943-1948
KRAFT: The man who decoded Diabetes and Heart Disease
…many decades ago.
2015 Ivor Cummins BE(Chem) CEng MIEI
PROPERLY DIAGNOSING DIABETES
2015 Ivor Cummins BE(Chem) CEng MIEI
1. FASTING BLOOD GLUCOSE TEST
PROPERLY DIAGNOSING DIABETES
A. Overnight Fast
2015 Ivor Cummins BE(Chem) CEng MIEI
1. FASTING BLOOD GLUCOSE TEST
PROPERLY DIAGNOSING DIABETES
A. Overnight Fast B. Blood glucose level
2015 Ivor Cummins BE(Chem) CEng MIEI
1. FASTING BLOOD GLUCOSE TEST
PROPERLY DIAGNOSING DIABETES
B. Blood glucose levelA. Overnight Fast
A. Overnight Fast
2015 Ivor Cummins BE(Chem) CEng MIEI
1. FASTING BLOOD GLUCOSE TEST
PROPERLY DIAGNOSING DIABETES
B. Blood glucose level
MISSES MOST – AND
WAY TOO LATE !
Ad

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Doctor Joseph Kraft Interview Slides - Father of Insulin Assay

  • 1. • Chairman, Department of Clinical Pathology and Nuclear Medicine • Chairman, Department of Pathology Pathologist & Director of Laboratories • Private Practice of Pathology • Consultant Pathologist • Pathologist & Director of Laboratories • Forensic Pathologist, Denver City & County • Assistant Professor, Department of Pathology, Colorado • Resident in Pathology, University of Colorado Medical Center • Captain, United States Army Medical Corps • Fellow: o College of American Pathologists o American Society of Clinical Pathologists o American College of Nuclear Physicians • 1972-1990 . • 1962 . • 1959-1961 • 1956-1959 • 1953-1959 • 1951-1953 . • 1951-1953 . • 1949-1951 . • 1943-1948 KRAFT: The man who decoded Diabetes and Heart Disease …many decades ago.
  • 2. 2015 Ivor Cummins BE(Chem) CEng MIEI PROPERLY DIAGNOSING DIABETES
  • 3. 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES A. Overnight Fast
  • 4. 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES A. Overnight Fast B. Blood glucose level
  • 5. 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES B. Blood glucose levelA. Overnight Fast
  • 6. A. Overnight Fast 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES B. Blood glucose level MISSES MOST – AND WAY TOO LATE !
  • 7. A. Overnight Fast 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES B. Blood glucose level 2. GLUCOSE TOLERANCE TEST A. 100g Glucose MISSES MOST – AND WAY TOO LATE !
  • 8. A. Overnight Fast 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES B. Blood glucose level 2. GLUCOSE TOLERANCE TEST B. Blood glucose level over timeA. 100g Glucose MISSES MOST – AND WAY TOO LATE !
  • 9. A. Overnight Fast 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES B. Blood glucose level 2. GLUCOSE TOLERANCE TEST B. Blood glucose level over timeA. 100g Glucose MISSES MOST – AND WAY TOO LATE !
  • 10. A. Overnight Fast 2015 Ivor Cummins BE(Chem) CEng MIEI 1. FASTING BLOOD GLUCOSE TEST PROPERLY DIAGNOSING DIABETES B. Blood glucose level 2. GLUCOSE TOLERANCE TEST B. Blood glucose level over timeA. 100g Glucose MISSES MOST – AND WAY TOO LATE ! MISSES MANY – AND WAY TOO LATE !
  • 11. 2015 Ivor Cummins BE(Chem) CEng MIEI 1. Drink 100g of Glucose…
  • 12. 2015 Ivor Cummins BE(Chem) CEng MIEI 2. Measure the INSULIN response over time… 1. Drink 100g of Glucose…
  • 13. 2015 Ivor Cummins BE(Chem) CEng MIEI 2. Measure the INSULIN response over time… 1. Drink 100g of Glucose… PROPER DIABETES DIAGNOSIS !
  • 14. 2015 Ivor Cummins BE(Chem) CEng MIEI
  • 15. 2015 Ivor Cummins BE(Chem) CEng MIEI
  • 16. 2015 Ivor Cummins BE(Chem) CEng MIEI
  • 17. 2015 Ivor Cummins BE(Chem) CEng MIEI
  • 18. 2015 Ivor Cummins BE(Chem) CEng MIEI Insulin Response Pattern 1 is: Euinsulinemia/Non-Diabetic Insulin Response Pattern 1 is: Euinsulinemia/Non-Diabetic
  • 19. 2015 Ivor Cummins BE(Chem) CEng MIEI Insulin Response Patterns 2 to 4 are: Hyperinsulinemia/Diabetes In Situ These people are Diabetic. Period.
  • 20. 2015 Ivor Cummins BE(Chem) CEng MIEI Insulin Response Patterns 2 to 4 are: Hyperinsulinemia/Diabetes In Situ These people are Diabetic. Period. Kraft tested 14,384 people
  • 21. 2015 Ivor Cummins BE(Chem) CEng MIEI Insulin Response Patterns 2 to 4 are: Hyperinsulinemia/Diabetes In Situ These people are Diabetic. Period. More than 75% of the people with ‘normal’ glucose results, failed Kraft’s test. They were NOT ok. Kraft tested 14,384 people
  • 22. 2015 Ivor Cummins BE(Chem) CEng MIEI Insulin Response Patterns 2 to 4 are: Hyperinsulinemia/Diabetes In Situ These people are Diabetic. Period. Kraft tested 14,384 people They were Diabetic More than 75% of the people with ‘normal’ glucose results, failed Kraft’s test. They were NOT ok.
  • 23. 2015 Ivor Cummins BE(Chem) CEng MIEI Critically, Kraft’s research and >3,000 autopsies (personally conducted) led him to infer that:
  • 24. 2015 Ivor Cummins BE(Chem) CEng MIEI • The damage of diabetes is vascular: you must assume diabetes is the root cause, unless Pattern 1 demonstrated! Critically, Kraft’s research and >3,000 autopsies (personally conducted) led him to infer that:
  • 25. 2015 Ivor Cummins BE(Chem) CEng MIEI • The damage of diabetes is vascular: you must assume diabetes is the root cause, unless Pattern 1 demonstrated! • The damage precedes the point where the glucose becomes elevated (ref: Kimmelsteil’s work) Critically, Kraft’s research and >3,000 autopsies (personally conducted) led him to infer that:
  • 26. 2015 Ivor Cummins BE(Chem) CEng MIEI • The damage of diabetes is vascular: you must assume diabetes is the root cause, unless Pattern 1 demonstrated! • The damage precedes the point where the glucose becomes elevated (ref: Kimmelsteil’s work) • This diabetic-driven disease is observed in all vessels, incl. micro vessels of the heart’s IV Septum Critically, Kraft’s research and >3,000 autopsies (personally conducted) led him to infer that:
  • 27. 2015 Ivor Cummins BE(Chem) CEng MIEI • The damage of diabetes is vascular: you must assume diabetes is the root cause, unless Pattern 1 demonstrated! • The damage precedes the point where the glucose becomes elevated (ref: Kimmelsteil’s work) • This diabetic-driven disease is observed in all vessels, incl. micro vessels of the heart’s IV Septum In summary, Kraft concluded that: “Those with cardiovascular disease not identified with diabetes…are simply undiagnosed.” Critically, Kraft’s research and >3,000 autopsies (personally conducted) led him to infer that:
  • 28. 2015 Ivor Cummins BE(Chem) CEng MIEI Kraft in Summary: 1.Diabetic phenomena are grossly under- diagnosed in the population 2.The earliest diagnosis is with the ‘5 hour glucose with insulin assay’ (although 2hr insulin can serve as a proxy) 3.The diabetic state can be effectively addressed with diet, rescuing people from Pattern 2-4 (Diabetes in Situ) 4.Cardiovascular Disease is primarily a diabetic pathology – all so afflicted should be assumed diabetic, unless they achieve Pattern 1… 5.The vascular disease of Penile Erectile Dysfunction (PED), is also a diabetic pathology – all so afflicted should be assumed diabetic, unless they achieve Pattern 1…