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Additives for happier poultry.
Borja Vilà & Joaquim Brufau
Monogastric Nutrition SubProgram
IRTA
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
1
Feed additives
# Regulated By EC 1831/2003
# Substances, micro-...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
2
Feed additives
Favorably affect animal production, performance ...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
3
EFSA Scientific opinion /Self-task FEEDAP/ 2008
# The purpose w...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
4
Brambell (1965) defined animal welfare in terms of
5 freedoms (...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
5
Brambell (1965) defined animal welfare in terms of
5 freedoms (...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
6
Brambell (1965) defined animal welfare in terms of
5 freedoms (...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
7
General Adaptation Syndrome, Selye 1950
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
8
Animal nutrition and Gut microflora interactions
(Animal protec...
9
Additives for happier poultry
Mas Bové, 15 & 16 May 2014
Philipe J. Sansonetti (2004) Institut Pasteur
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
10
Mucosal surfaces place for “dialogue”
The intestinal epitheliu...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
11
Williams, 2005
Integrated disease management by maintenance of...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
12
Choct (2006) Australia, Gordon Memorial Lecture
Gut health int...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
13
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
14
Tactacan et al (2013) USA
Probiotic (Bacillus subtilis QST 713...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
15
Francesch et al 2006
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
16
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
17
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
18
De Jong et al (2014) Wageningen
Wet litter → increases footpad...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
19
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
20
Francesch & Brufau
2004
WPSJ 60:64-75
WET
LITTER
Management & ...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
21
Feed restriction
Broiler breeders
De Jong and Guémené (2011) W...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
22
Olfaction
Jones, R. B., and T. J. Roper. (1997) UK
Palatabilit...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
23
Ammonia
Ammonia
Khempaka et al (2013) Thailand
Dry peppermint ...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
24
Flies
Flies
Ruiu et al (2014) Italy
Brevibacillus laterosporus...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
25
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
26
Efficacy assessment on immune response
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
27
Figure 1. Scanning electron micrographs of the intestine of
Co...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
28
Prebiotic activity
CBG reduced the
presence of Salmonella
in c...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
29
Suggested End-points for Efficacy demonstration/
Animal welfar...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
30
Are we able to answer all the questions generated ?
The most i...
Mas Bové, 15 & 16 May 2014
Additives for happier poultry
31
Monogastric Nutrition subprogram
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Sponsor Day on animal feeding: Additives for happier poultry

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Sponsor Day: Seminar on Animal Feeding
15th-16th May 2014
IRTA Mas Bover

Published in: Technology, Business
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Sponsor Day on animal feeding: Additives for happier poultry

  1. 1. Additives for happier poultry. Borja Vilà & Joaquim Brufau Monogastric Nutrition SubProgram IRTA
  2. 2. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 1 Feed additives # Regulated By EC 1831/2003 # Substances, micro-organisms or preparations, other than feed material and premixtures, which are intentionally added to feed or water in order to perform, in particular, one or more of the functions mentioned in Article 5(3): 1. Favorably affect the characteristics of feed or animal products 2. Favorably affect the color of ornamental fish and birds 3. Satisfy the nutritional needs of animals 4. Favorably affect animal production, performance or welfare 5. Have a coccidiostat or histomonostatic effect
  3. 3. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 2 Feed additives Favorably affect animal production, performance or welfare reduction of morbidity is considered a legitimate attribute of a feed additive as it „favorably affects‟ animal welfare
  4. 4. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 3 EFSA Scientific opinion /Self-task FEEDAP/ 2008 # The purpose was to :  examine the scientific basis for the existing functional groups  propose, if necessary, based on this review, the establishment of additional functional groups (or categories). # Potential new categories  Additives which favorably affect animal welfare: Metabolic regulators, Immune-modulators, Detoxifiers, Other (inclusion of coccidiostats & histomonostats?)  Additives which improve product quality: Microbial contamination controllers, Nutritional value enhancers, Sensory additives
  5. 5. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 4 Brambell (1965) defined animal welfare in terms of 5 freedoms (Farm Animal Welfare Council, 1992): 1) freedom from hunger and thirst 2) freedom from discomfort 3) freedom from pain, injury, and disease 4) freedom to express normal behavior 5) freedom from fear and stress
  6. 6. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 5 Brambell (1965) defined animal welfare in terms of 5 freedoms (Farm Animal Welfare Council, 1992): 1) freedom from hunger and thirst 2) freedom from discomfort 3) freedom from pain, injury, and disease 4) freedom to express normal behavior 5) freedom from fear and stress
  7. 7. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 6 Brambell (1965) defined animal welfare in terms of 5 freedoms (Farm Animal Welfare Council, 1992): freedom from fear and stress All farm animals experience some level of stress during their lives that reduces their fitness failing to achieve performance standards, or even through disease and death” (Rostagno 2009) Environment stress & feed stress → pathogen behavior
  8. 8. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 7 General Adaptation Syndrome, Selye 1950
  9. 9. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 8 Animal nutrition and Gut microflora interactions (Animal protection). Andrew Chesson
  10. 10. 9 Additives for happier poultry Mas Bové, 15 & 16 May 2014 Philipe J. Sansonetti (2004) Institut Pasteur
  11. 11. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 10 Mucosal surfaces place for “dialogue” The intestinal epithelium: an interactive barrier  Physical barrier  Innate immunity  Adaptive immunity Crosstalk between commensals and mucosa Crosstalk between pathogens and mucosa
  12. 12. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 11 Williams, 2005 Integrated disease management by maintenance of gut integrity
  13. 13. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 12 Choct (2006) Australia, Gordon Memorial Lecture Gut health intimately associated with:  Macro & micro structural integrity  Immunology  Microbiology  Nutrient supply Influenced by hygiene conditions, feed additives & stress Subclinical infections (like Necrotic Enteritis) compromise the gut health
  14. 14. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 13
  15. 15. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 14 Tactacan et al (2013) USA Probiotic (Bacillus subtilis QST 713) to decrease the incidence of Necrotic Enteritis  production of bacteriocins & other antimicrobial compounds  immunomodulation, increase in gut associated lymphoid tissue
  16. 16. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 15 Francesch et al 2006
  17. 17. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 16
  18. 18. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 17
  19. 19. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 18 De Jong et al (2014) Wageningen Wet litter → increases footpad dermatitis (walking ability) decreases overall welfare & also carcass yield Dry litter vs wet litter → improved gross margin by 9 cents / bird Su et al (2013) China High stocking density →decreased walking ability higher incidence of leg problems, lower activity and more resting, breast & skin lesions Higher levels of vit D3 alleviated welfare problems but not growth impairment Wideman el al (2012) Arkansas & Austria Development of a lameness model → effect of probiotics to counteract lameness
  20. 20. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 19
  21. 21. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 20 Francesch & Brufau 2004 WPSJ 60:64-75 WET LITTER Management & Housing Litter Temperature/humidity Ventilation Drinkers Density Diseases Coccidiosis Enteritidis Colibacilosis Campylobacter Dietary factors Protein level Electrolyte balance Ionophors Viscosity By-products Feed technology
  22. 22. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 21 Feed restriction Broiler breeders De Jong and Guémené (2011) Wageningen & INRA → chronic hunger → fibrous diets, appetite suppresant Molting Gutierrez el al (2008) Texas A&M (Dr Bailey group) → hunger, increased susceptibility to Salmonella → guar meal +enzymes, wheat middlings Pre-slaughter Menconi et al (2014) Arkansas, Mexico, Brazil, Argentina → dehydration, mortality, Salmonella, meat quality → OA in water
  23. 23. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 22 Olfaction Jones, R. B., and T. J. Roper. (1997) UK Palatability of feed and water →Also to sense familiarity and danger Welfare improved through olfaction? → familiar and pleasant smells from rearing also found in laying facilities (aromatic oils)
  24. 24. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 23 Ammonia Ammonia Khempaka et al (2013) Thailand Dry peppermint in feed  Decreased ammonia concentration  Improved carcass quality
  25. 25. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 24 Flies Flies Ruiu et al (2014) Italy Brevibacillus laterosporus 1010 spores/g feed  80% reduction in flies  Increased soil fertility  Plant root protection from pathogens & parasite
  26. 26. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 25
  27. 27. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 26 Efficacy assessment on immune response
  28. 28. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 27 Figure 1. Scanning electron micrographs of the intestine of Control animals (uninoculated birds feeding the basal diet). A to C, ileum and D, cecal tonsil. Figure 3. Scaning electron micrographs of the intestine of Salmosan-fed animals (inoculated birds feeding the basal diet plus Salmosan 1 g/kg). A, C and D, ileum and B, cecal tonsil. In C, the arrowhead indicates a goblet cell and the inset is a transmission electron micrograph of the same zone in which the arrowhead also indicates a goblet cell. βGM → goblet cells and mucus production →Salmonella adhesion also reduced M cells (characteristic of infected animals) Also greater villus length
  29. 29. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 28 Prebiotic activity CBG reduced the presence of Salmonella in challenged birds YCW increased performance by favoring intestinal mucosal development
  30. 30. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 29 Suggested End-points for Efficacy demonstration/ Animal welfare  In vitro studies: (majority of the experimental conducted until now). However they are essential for the first step  In vivo studies: to conduct studies with animals under certain conditions and to look the benefits of the products on the mucosal and epithelial cells from intestine. Morphology, Immunity reaction and microflora development. The animal performances studies may be also involved in order to justify the interaction
  31. 31. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 30 Are we able to answer all the questions generated ? The most important action will be to understand the interaction between Animal welfare and the concept of stress and the physiology of the gastrointestinal tract. Animal health improvement is difficult to assess , especially when we are dealing with benefits of Feed Additives in order to satisfy Animal welfare indicators. The indicators should be clearly well identified under stress conditions first. Immune indicators must be considered to determine the degree of animal defense in order to prevent damage by the stressors.
  32. 32. Mas Bové, 15 & 16 May 2014 Additives for happier poultry 31 Monogastric Nutrition subprogram

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