Amir naiberg

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  • Innovation Capacity score
  • Amir naiberg

    1. 1. Technology Transfer from the Weizmann Institute of Sciencefrom our pipeline to your bottom lineAmir Naiberg, CEOYeda Research & Development Co. Ltd.Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    2. 2. The Weizmann Institute of ScienceDiscovering Basic Science Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science from the Weizmann Institute of Science w w w.YedaRnD .c om w w w .Yeda R n D .com
    3. 3. Weizmann Institute of Science Curiosity Driven ResearchYeda Research & Development Co. Ltd.Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    4. 4. What will be Who will the next make the scientific next scientific revolution? revolution?Yeda Research & Development Co. Ltd.Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    5. 5. The next scientific revolution will be • driven by scientists who have a multidisciplinary view of science • the opportunity to take risks • the infrastructure to work • the freedom to thinkYeda Research & Development Co. Ltd.Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    6. 6. The Weizmann Institute of ScienceThe Pool of knowledge Mathematics Computer Chemistry Biology Science Physics Biochemistry Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    7. 7. The Weizmann Institute of ScienceQuality Driven Average number of citations per paper Technion TAU HUJ WIS BGU “Best Place in Academia” BIU ranked No.1 in 2011 among top International academic Haifa Institutions” TheScientist.com Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    8. 8. ERC Starter+Established 2007-2010 35 30 25 Success Rate (%) 20 15 10 5 0 Weizmann Technion Hebrew Tel Aviv Ben Gurion Bar Ilan Haifa Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    9. 9. The Need to Rethink Innovation Company Total R&D Spending 1997-2011 R&D Spending Per Number of Drugs ($Mil) Drug ($Mil) Approved AstraZeneca 58,955 11,790.93 5 GlaxoSmithKline 81,708 8,170.81 10 Sanofi 63,274 7,909.26 8 Roche Holding AG 85,841 7,803.77 11 Pfizer Inc. 108,178 7,727.03 14 Johnson & Johnson 88,285 5,885.65 15 Eli Lilly & Co. 50,347 4,577.04 11 Abbott Laboratories 35,970 4,496.21 8 Merck & Co Inc 67,360 4,209.99 16 Bristol-Myers Squibb Co. 45,675 4,152.26 11 Novartis AG 83,646 3,983.13 21 Amgen Inc. 33,229 3,692.14 9 Total 802,468 5,773 139 Sources: InnoThink Center For Research In Biomedical Innovation; Thomson Reuters Fundamentals via FactSet Research Systems The Truly Staggering Cost Of Inventing New Drugs, Matthew Herper (Forbes, 10.2.2012) Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    10. 10. The Israel National Centerfor Personalized Medicine BENCH TO BEDSIDE Enhancing medical treatment efficacy using the most advanced research tools Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    11. 11. Personalized Medicine – What is it? Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    12. 12. The Israel National Center for Personalized MedicineInfrastructure Sequencing Unit Proteomics Unit Building on the Weizmann Crown Arising from the Weizmann Advanced Human Genome Center, the unit will Mass Spectrometry Lab, the unit will provide High Throughput DNA/RNA provide quantitative proteomics sequencing and affiliated analyses to study differential bioinformatics to analyse genomic expression and post-translational variations, transcriptomes, non-coding modifications of proteins. RNAs, and editomes. Bioinformatics Unit Small Molecules Screening Unit Build on the Bioinformatics and Incorporating the Weizmann Structural Biological Computing Group at Proteomics Unit for protein production Weizmann, the unit will use advanced and structure determination tools to identify promising gene capacities, the unit will screen small targets, key proteins and molecule and siRNA libraries for critical pathways. desired biological effects. Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    13. 13. Yeda Research & Development Co. Ltd.Bridging Research & Development Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science from the Weizmann Institute of Science w w w.YedaRnD .c om w w w .Yeda R n D .com
    14. 14. Yeda = Knowledge Applied Basic Top Down Bottom up Demand driven Curiosity driven Secrecy Publish or Perish Short term Long term Risk taking Avoid commercial risks Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    15. 15. Yeda Research & Development Co. Ltd.A World Leader in Technology Transfer  Dozens of “Weizmann-Inside” products on the market.  Total annual royalty-generating sales in 2011: Over $15 Billion.  Over 50 new companies were established around Yeda’s technologies.  Yeda owns the largest portfolio of patents in Israel: 560 live patent families, with more than 1,700 patent families filed since 1971. Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    16. 16. Israeli Patents in the USA (Accumulated for the Years 2006-2010)450 403400350 325300250200 164 144 141150 95 90 87100 77 77 63 62 61 61 57 5750 0Yeda Research & Development Co. Ltd. Source: BDITechnology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    17. 17. Governmental Support Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    18. 18. Innovation Capacity ScoreEnterprise Supportencourages growth ofdomestic biotechnologystartups and lures foreigncompanies to establishfacilities domestically.Source: SCEINTIFICAMERICAN/WORLDVIEW 2010 Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    19. 19. Intervention Programs KAMIN 60% 85% 60% 90% Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    20. 20. The Role of Governments  Financial support for academic, basic research. Public support is essential for academic freedom.  Intervention programs for “bridging the gap”.  Legal infrastructure: intellectual property rights (IPR) laws, Taxations, corporate law, etc.  Fixing market failures. Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    21. 21. Global vs. Local Science is inherently global: it is like parachute, it only functions when open; Scientists look for the international collaborators which most fit their research needs. Industry aims at global markets; it looks for the best international deals. Governments act Locally – for national growth, for the local industry, for jobs creation, etc.=> Government involvement is against internationalization of R&D. Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    22. 22. Government’s involvement in university-industry relations  Under the responsibility of the office of the Chief Scientist at the ministry of Industry, Trade and Labor (OCS).  Different intervention programs for university-LOCAL industry collaboration.  Restrictions on exporting of knowledge created under these programs. Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    23. 23. Summary Israel’s example has shown that successful global TT can go together with excellent science and bring products to the marketplace. Acting globally scientifically and the freedom of operation of the TTOs’ were essential for this success and brought investments to Israel. Lately, government’s policy is more dominant, trying to encourage LOCAL TT. EU, as a superstructure, should support cross border technology transfer. Yeda Research & Development Co. Ltd. Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om
    24. 24. www.YedaRnD.com Thank youYeda Research & Development Co. Ltd.Technology Transfer from the Weizmann Institute of Science w w w .Yeda R n D .c om

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