Fibro-osseous lesions are diverse group of processes
that are characterized by replacement of normal bone
by fibrous tissue containing a newly formed
Pindborg and Kramer s classification
Charles Waldron (1993)
Brannon and fowler
Slootweg and Muller (1996)
Fibrous dysplasia is a benign lesion, presumably
developmental in nature, characterized by a presence
of fibrous connective tissue with a characteristic
whorled pattern and containing trabeculae of
immature bone. (W.H.O )
Marx and Stern(2003)
Philip et al (1997) classified fibrous dysplasia into
1. Monostotic F.D
2. Polyostotic F.D
Jaffe s type
Depends upon the degree of lesions maturation
All the three exhibit similar features.
The tissue consists of fragments of cellular
mesenchymal tissue composed of spindle shaped
fibroblasts and collagen fibres with numerous small
blood vessels and free hemorrhage.
Within this background, a mixture of woven
bone, lamellar bone and cementum like material is
With maturation the ratio of fibrous tissue
background to mineralized material decreases.
Pindborg J.J11 (1965) defines ossifying fibroma as a
sharply demarcated, intraosseous benign tumour that
occurs in a single bone and shows gradual
transformation of a cell rich connective tissue in to bone
The lesion consists of fibrous tissue that
exhibits varying degrees of cellularity and
contains mineralized material in the form
of trabeculae of osteoid, bone or
The trabeculae vary in size and frequently
show a mixture of woven & lamellar
patterns, peripheral osteoid and
osteoblastic rimming, peripheral brush
borders that blend into adjacent bone.
Variation in the type of mineralized
material differentiates it from fibrous
Treatment and prognosis
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15. TB of Differential diagnosis –Wood and Goaz
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17. TB of Oral pathology - William Shafer