www.in-ADME.com              in-ADME Research                pCEL-X Rev 3.1                  Overview         1. Atenolol ...
Caco-2 Refinement Examplepage 2                in-ADME   Research   Copyright © 2011 
page 3   in-ADME   Research   Copyright © 2011 
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Simulation Examplepage 16            in-ADME   Research   Copyright © 2011 
page 17   in-ADME   Research   Copyright © 2011 
page 18   in-ADME   Research   Copyright © 2011 
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Refinement of in situ Datapage 29                  in-ADME   Research   Copyright © 2011 
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BD Pre-Coated PAMPA Platespage 36               in-ADME   Research   Copyright © 2011 
Thin Membranes Leak Water & Can’t be Stirredpage 37                                                  in-ADME   Research   ...
Thin Membranes Leak Water & Can’t be Stirredpage 38                                                  in-ADME   Research   ...
Thin Membranes Leak Water & Can’t be Stirredpage 39                                                  in-ADME   Research   ...
Thin Membranes Leak Water & Can’t be Stirredpage 40                                                  in-ADME   Research   ...
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in-ADME Research pCEL-X slides

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Sample screen shots from pCEL-X program for permeability anlaysis of Caco-2, PAMPA, and BBB

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in-ADME Research pCEL-X slides

  1. 1. www.in-ADME.com in-ADME Research pCEL-X Rev 3.1 Overview 1. Atenolol Caco-2 Refinement 2. Amitriptyline Caco-2 Simulation 3. Amitriptyline in situ brain perfusion Refinement 4. BD Pre-coated PAMPA Plates Leak Presentation Copyrighted (C) 2011. in-ADME Research. All rights reserved.page 1 in-ADME Research Copyright © 2011 
  2. 2. Caco-2 Refinement Examplepage 2 in-ADME Research Copyright © 2011 
  3. 3. page 3 in-ADME Research Copyright © 2011 
  4. 4. page 4 in-ADME Research Copyright © 2011 
  5. 5. page 5 in-ADME Research Copyright © 2011 
  6. 6. page 6 in-ADME Research Copyright © 2011 
  7. 7. page 7 in-ADME Research Copyright © 2011 
  8. 8. page 8 in-ADME Research Copyright © 2011 
  9. 9. page 9 in-ADME Research Copyright © 2011 
  10. 10. page 10 in-ADME Research Copyright © 2011 
  11. 11. page 11 in-ADME Research Copyright © 2011 
  12. 12. page 12 in-ADME Research Copyright © 2011 
  13. 13. page 13 in-ADME Research Copyright © 2011 
  14. 14. page 14 in-ADME Research Copyright © 2011 
  15. 15. page 15 in-ADME Research Copyright © 2011 
  16. 16. Simulation Examplepage 16 in-ADME Research Copyright © 2011 
  17. 17. page 17 in-ADME Research Copyright © 2011 
  18. 18. page 18 in-ADME Research Copyright © 2011 
  19. 19. page 19 in-ADME Research Copyright © 2011 
  20. 20. page 20 in-ADME Research Copyright © 2011 
  21. 21. page 21 in-ADME Research Copyright © 2011 
  22. 22. page 22 in-ADME Research Copyright © 2011 
  23. 23. page 23 in-ADME Research Copyright © 2011 
  24. 24. page 24 in-ADME Research Copyright © 2011 
  25. 25. page 25 in-ADME Research Copyright © 2011 
  26. 26. page 26 in-ADME Research Copyright © 2011 
  27. 27. page 27 in-ADME Research Copyright © 2011 
  28. 28. page 28 in-ADME Research Copyright © 2011 
  29. 29. Refinement of in situ Datapage 29 in-ADME Research Copyright © 2011 
  30. 30. page 30 in-ADME Research Copyright © 2011 
  31. 31. page 31 in-ADME Research Copyright © 2011 
  32. 32. page 32 in-ADME Research Copyright © 2011 
  33. 33. page 33 in-ADME Research Copyright © 2011 
  34. 34. page 34 in-ADME Research Copyright © 2011 
  35. 35. page 35 in-ADME Research Copyright © 2011 
  36. 36. BD Pre-Coated PAMPA Platespage 36 in-ADME Research Copyright © 2011 
  37. 37. Thin Membranes Leak Water & Can’t be Stirredpage 37 in-ADME Research Copyright © 2011 
  38. 38. Thin Membranes Leak Water & Can’t be Stirredpage 38 in-ADME Research Copyright © 2011 
  39. 39. Thin Membranes Leak Water & Can’t be Stirredpage 39 in-ADME Research Copyright © 2011 
  40. 40. Thin Membranes Leak Water & Can’t be Stirredpage 40 in-ADME Research Copyright © 2011 

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