Invited speech of Dr. Totti Könnölä, CEO inf Insight Foresight Institute in the scientific conference 'Bioengineering for Healthy Ageing. Adding Life to Years' November 9th 2017, CosmoCaixa Barcelona. Future personal health ecosystems encompass various areas of application such as chronic disease management, life-style management, independent living and emergency services. Such future systems assist in the provision of continuous, quality controlled and personalised health services to empowered individuals regardless of location and provide a horizontal development area across variety of patients, clinical specialties, technology fields and health services. Hence, the development of such ecosystems requires transformative governance that enable coordination and federation of diverse stakeholders.