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  1. 1. Ibogaine<br />Presented by Rachel Jordan<br />
  2. 2. What is Ibogaine?<br />A naturally occurring psychoactive plant alkaloid<br />It is sourced from the roots of the plant TabernantheIboga that grows in the forests of West Africa<br />TabernantheIboga plant<br />
  3. 3. Ibogaine’s History<br />Traditionally used for thousands of years as a catalyst for spiritual exploration and healing by the African Bwiti culture.<br />
  4. 4. Ibogaine’s History<br />Howard S. Lotsof first discovered Ibogaine’s ability to disrupt chemical dependency in 1962-63<br />Ever since, he has been researching everything about it and advocating for it’s use in treating addiction<br />As of March 2007, 12 people out of 3611 died in relation to Ibogaine treatment but also in relation to other factors<br />Has been used to treat chemical dependence for over 40 years and has a 65% abstinence rate over 10% with conventional drug treatment programs<br />No potential for abuse<br />
  5. 5. Ibogaine’s action <br /><ul><li> Has been shown to bind with multiple </li></ul> neurotransmitter sites within the CNS<br /><ul><li> Increases serotonin and decreases/blocks </li></ul> dopamine<br /><ul><li> Has been shown to act both as an </li></ul> antagonist and an agonist as well as <br /> directly and indirectly<br />
  6. 6. Ibogaine’s Effects<br />Works in two ways:<br />Reduction of withdrawal symptoms & cravings & sustained periods of abstinence or reduced use<br />Produces a subjective experience where the person may undergo processes where their life & choices are examined & reassessed<br />
  7. 7. Forms and Dosage<br />Botanical root bark<br />Total alkaloid extract<br />Purified Ibogaine HCl (99.4% purity)<br />Doses are determined on an individual patient basis and are based on kg as well as addiction severity. Normal dosing is usually 15-20mg/kg for full therapeutic effect<br />Cost is roughly $4700-$4900 for 5 day treatment program on Vancouver Island<br />
  8. 8. Ibogaine Administration<br />An oral capsule<br />Takes approx. 45 minutes to take effect & decrease withdrawal symptoms<br />Should be taken in place of next narcotic dose <br />Blood pressure & pulse should be checked every 30 min for first 4-8 hours & then if stable, every hour thereafter<br />Effects occur in 3 stages and can last up to 36 hours<br />
  9. 9. First Stage<br />Patient will usually want to lay prone & still as may experience motion related N&V<br />Skin tends to become numb<br />May hear an initial buzzing or oscillating sound<br />A period of dream-like visualization may last for 3 to 4 hours & ends abruptly should it occur at all<br />May experience random flashes of light that appear everywhere with eyes open & may last for hours or days. Visualization on the other hand is most common with eyes closed. <br />
  10. 10. Second stage<br />Follows visualization & has been described as one in which the patient principally experiences cognitive evaluation or a review of issues that are important to them<br />They may cover every possible scenario from early childhood experiences to current health issues & may last for as few as 8 hours or for 20 hours or longer. <br />
  11. 11. Third Stage<br />Also known as Residual Stimulation stage<br />It tends to leave the patient exhausted & therefore is somewhat uncomfortable<br />May remain awake for two or more days but most patients will sleep within 24-48 hours of Ibogaine administration<br />Usually, there is a long term diminishment of the need for sleep over weeks or months<br />Some patients may require or request sedation <br />
  12. 12. Side Effects<br />Coordination disturbances (unstable gait and tendency to fall)<br />Hallucination-like experiences <br />Sleep disturbances<br />Concentration & speech troubles<br />Heart rate & blood pressure changes<br />Nausea & vomiting<br />Dizziness <br />Light sensitivity<br />Tiredness<br />Muscles soreness<br />
  13. 13. Post Ibogaine Treatment Therapy<br />Patients are encouraged to attend NA or AA meetings for further support<br />Many are encouraged to have supports &/or resources in place before detox-ing<br />Other additional treatment therapies <br />
  14. 14. Contraindications<br />History of heart attacks or cardiovascular disease/abnormalities<br />Concurrent opiate/stimulant drug use<br />Active psychological or neurological disorders<br />Beck Depression Inventory score &gt; 24 <br />Active TB or pregnancy<br />Impaired kidney, liver or GI function <br />Concurrent drugs that may cause adverse ibogaine/drug interactions <br />
  15. 15. PHN Role<br />Know use/effects of Ibogaine in case a client inquires about it or presents themselves on it<br />Advocate for its use/funding in addictions treatment through a harm reduction, health promotion perspective<br />Educate the public and patients on benefits & risks of Ibogaine compared to conventional treatments so they can make the best choice possible & can advocate for themselves & others<br />Know difference b/w opioid withdrawal & Ibogaine’s effects<br />
  16. 16. Q & A !!<br />Where does Ibogaine originate from?<br />Who qualifies for Ibogaine treatment?<br />How long does the therapy typically last?<br />What are the two main ways that Ibogaine works on treating chemical dependence?<br />How many different forms are there?<br />How is it typically taken?<br />What should a nurse do while taking care of a person on Ibogaine?<br />
  17. 17. References<br />Ibogaine Association. (2006). Retrieved February 27, 2008 from<br />Ibogaine Research Project. (2005). Retrieved February 27, 2008 from<br />Ibogaine Roots of Hope: CBS. Retrived from Veoh videos and internet television at<br />Ibogaine Therapy House. (2008). Retrieved February 27, 2008 from<br />Multidisciplinary Association for Psychedelic Studies. (2007). Ibogaine studies and research projects. Retrieved February 27, 2008 from<br />Roslin, A. (2007, Oct. 25). THE QUEST FOR THE ULTIMATE CURE FOR ADDICTION.The Georgia Straight. Retrieved February 27th, 2008 from <br />The Ibogaine Dossier. (1999). Retrieved February 27, 2008 from<br />