Neuromotor disorder general view: make it easy

2,404 views

Published on

Published in: Health & Medicine
0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total views
2,404
On SlideShare
0
From Embeds
0
Number of Embeds
2
Actions
Shares
0
Downloads
42
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide
  • Major neurotransmitters: glutamate (excitatory) and GABA (inhibitory)Damage results in weakness, with loss of voluntary movements especially fine, skilled movements, but preservation of other forms of movements including segments reflexesThey both (1-2) receive input from several motor and sensory cortical areas and project back to the cerebral cortex via the thalamus. They integrate and modulate motor activity primarily through the cerebral cortex and direct activation pathways.
  • Final common pathway – many motor units through which all activities in the motor system must act
  • central causes : Cerebral palsy as cerebellar or atonic diplegiaCP, , syndromes as Down syndrome or Prader Willi syndrome, neurodegenerative or neurometabolic disorders
  • Neuromotor disorder general view: make it easy

    1. 1. NEURO-MOTOR SYSTEMProf Dr Hussein AbdeldayemProf and Chief of Ped Neurology Unit,alex university
    2. 2. CPAFP= GBSFLOPPY BABY: SMA
    3. 3. ACUTE FLACCID PARALYSIS AFP Dr Hussein Abdeldayem, MD Professor of Pediatric Neurology
    4. 4. UMNL L M N L Brain (pyramidal NM AHC PNs Musclescells and junction tracts)
    5. 5. Anatomy1- UML
    6. 6.  Control Circuits  1-cerebellum : motor and premotor areas  2-basal ganglia control and modify motor activity- prevent invol movements  3- cerebellum
    7. 7. LMNL Motor unit – a lower motor neuron (ventral horn cell/CN nucleus) + muscle fibers under its control  alpha motor neuron AHC  Root (anterior)  axon (nerve)  MN synapse  muscle fibers AHC
    8. 8. CEREBRAL MOTOR DISORDER• CEREBRAL PALSY
    9. 9. C/P SUGGESTIONS • Cognitive dysfunctions as GDD/MR • Language delay • Seizures• TONE:PYRAMIDAL:SPASTICEXTRPYRAMIDAL: LEADPIPE/cogwheelCEREBELLUM: HYPOTONIA INVESTIGATION BRAIN MRI
    10. 10. LMNL CAUSES• AHC: 1- GENETIC: SMA 2- ACQUIRED : polio• Roots and Peripheral Nerves: genetic: myelocele, HSMN acquired: GBS (post-infectious), PNitis
    11. 11. • N-M junction: genetic: Myasthenia Gavis Acquired: botulinum toxin• Muscular: congenital: Myopathy, DMD acquired: myositis
    12. 12. C/P SUGGESTIONS• Normal Brain Function with only Motor Dysfunction ( Motor Delay)• Atonia: Floppy/ hypotonia• Areflexia

    ×