Ist scientific possibilities_200911_web-2

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Ist scientific possibilities_200911_web-2

  1. 1. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com MediSapiens Oy Scientific possibilities of IST database 20. September 2011
  2. 2. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com Stratify your patients with thousands of others Genomic signature for chromosomal instability Hundredsofpatients High Medium Low Data from your patiens? Worst prognosis? Resistant for therapy? Best prognosis?
  3. 3. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com New therapy target for Ewing’s sarcoma?
  4. 4. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com Novel breast cancer associated gene Only three publications in PubMed (none brca associated)
  5. 5. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com High ectopic expression in variety of cancers
  6. 6. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com Key EMT regulator and miRNA target in Brca
  7. 7. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com Nearly unknown MMP related gene
  8. 8. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com Known cell cycle player – new target for Burkitt’s lymphoma therapy?
  9. 9. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com Significant subsets of patients in multiple cancers for a known phosphatase downstream of KRAS
  10. 10. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com We have a patent pending algorithm* that enables you to compare your samples with over 15 000 fully annotated cancer samples. Here we see three commonly used melanoma cell lines, and how their gene expression matches actual in vivo samples, with regards to melanoma specific genes. * Kilpinen et al. BioData Mining 2011, 4:5 Ojala et. al. Genome Medicine, In Press Are you sure your model actually models the cancer you study?
  11. 11. Copyright © 2011 MediSapiens Ltd. All rights reserved. • medisapiens.com IST Online
  12. 12. Copyright © 2011 MediSapiens Ltd. All rights reserved. • www.medisapiens.com MediSapiens Ltd. Biomedicum Helsinki Tukholmankatu 8A FIN-00290 Helsinki +358 50 363 1848 contact@medisapiens.com medisapiens.com

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