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Skincerity Clinical Studies Summary Improve Skin Health

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Skincerity Clinical Studies Summary Improve Skin Health

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Skincerity Clinical Studies Summary Improve Skin Health

  1. 1. Overnight Treatment to Improve Skin Health & TextureNovel Polymer Advancement in Barrier Function Technologyv3.6-0110PRODUCT TESTINGThe Skincerity technology has beenextensively tested by world-renowneddermatologists at leading University MedicalCenters to determine product effectivenessand verify product safety.√ Product Safety – An FDA-recommendedtest verified that the barrier technology issafe and causes no irritation to the skin.This clinical study was initiated andcompleted under grants from the NationalInstitutes of Health (SBIR No. AR44435) todetermine if the skin coating causedadverse skin irritation.Another study initiated by the NIH provedthat the barrier technology can act as abarrier to irritants that cause contactdermatitis. When applied to irritated skin,the coating has the affect of improving skinfunction.VALIDATION√ Enhances Other Products – BecauseSkincerity’s barrier technology wasdeveloped as a drug delivery platform, itcan be used effectively alone or with otherproducts. It actually intensifies the deliveryof other product’s nutrients and antioxidantsto the skin. The efficacy was validated in aDepartment of Dermatology, University ofUtah School of Medicine, clinical study.The study was initiated and completedunder grants from the National Institutes ofHealth (SBIR No. I041777).The objective of the research was tocompare the barrier technology withMiconazole against an over-the-counterMiconazole Nitrate cream.Data from the study showed conclusivelythat the barrier formulation was substantiallymore effective in delivering a higher drugcontent into the skin.This study suggests that using Skinceritywith a favorite nighttime product (such as amoisturizer) can make the additionalproduct even more effective.SKINCERITY® HISTORY AND SCIENCESkincerity is an authentic medicalbreakthrough that can be used alone orwith your favorite nightime products.The cornerstone science of Skincerity is arevolutionary breathable polymer skinbarrier that makes topical drugs moreeffective.This unique skin coating formulation wasengineered by Biomedical DevelopmentCorporation and has been validated indermatologic research studies supported bythe National Institutes of Health.The evolution of Biomedical’s pioneeringscience is Skincerity, which uses the sameskin coating foundation to make dramaticimprovements in the way your skin looksand feels.The breathable barrier actually mimics theskin. The micro-porous film works while yousleep to hold in the skin’s natural moistureand and simultaneously allow the skin tobreathe.The design of the coating technology alsoamplifies the delivery of anti-aging nutrientsand antioxidentsSkincerity is the perfect instrument to savethe skin’s natual moisture and reduce theappearance of wrinkles. It also works ondry, damaged skin, acne, rashes, scars,and insect bites.√ Visible Improvement – Skincerity makesa genuine difference in the appearance ofwrinkles (skin texture). Using the barriertechnology with vitamin E, a clinical studyon hands was initiated with sixty-six womenand one man to determine effectiveness.Quantitative results evaluated by theUniversity of Texas Health Science Centerat San Antonio, Texas, indicated that 67%of all people using Skincerity experiencedan average reduction in the appearance ofwrinkles by 39% with some improving asmuch as 200%.The outcome of the study was so dramaticthat the results were published andpresented to dermatologists at the 2005American Academy of Dermatology annualmeeting in New Orleans.48423630241812600123456789Miconazole nitrate creamMiconazole in novel polymer vehiclemean, n=6Hours after applicationµg/sqcmresidual product removal***** **Figure 1. Miconazole Nitrate Cream, 2% vs.Miconazole Base In A Novel Polymer Vehicle, 1.738%Breathable BarrierMore EffectiveMicroscopic ViewShows that the BarrierMimics the Skin…Holding in VitalMoisture and Allowingthe Skin to BreatheTransepidermal water loss (TEWL) recorded-60 -30 0 30 60 90 120 150 180 210 240PercentChange010203040NumberofPatients0.00.10.20.30.40.5ProportionperBarImprovement-60 -30 0 30 60 90 120 150 180 210 240PercentChange010203040NumberofPatients0.00.10.20.30.40.5ProportionperBarImprovement-60 -30 0 30 60 90 120 150 180 210 240PercentChange010203040NumberofPatients0.00.10.20.30.40.5ProportionperBar-60 -30 0 30 60 90 120 150 180 210 240PercentChange010203040NumberofPatients0.00.10.20.30.40.5ProportionperBarImprovement-60 -30 0 30 60 90 120 150 180 210 240PercentChange010203040NumberofPatients0.00.10.20.30.40.5ProportionperBarImprovementAverage Reductionin the Appearanceof Wrinkles by 39%

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