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Histology ofHistology of
Large IntestineLarge Intestine
ByBy
Muhammad Adan AsgharMuhammad Adan Asghar
ObjectivesObjectives::
--Basic Histology of OrgansBasic Histology of Organs
--Histogenisis of Large IntestineHistogenisis ...
ORGANORGAN
SS
SOLIDSOLID
--stromastroma
--parenchymaparenchyma
HOLLOWHOLLOW
--mucosamucosa
--submucosasubmucosa
--muscular...
Histology of GITHistology of GIT
 Schematic diagram showing differentSchematic diagram showing different
layers of GITlay...
TractTract
Common Characteristics:
o Hollow tube composed of a lumen whose diameter
varies.
o Surrounded by a wall made up...
The large intestineThe large intestine
 The large intestine formed of theThe large intestine formed of the
following orga...
The function of theThe function of the
large intestinelarge intestine
The absorption of waterThe absorption of water
Exclu...
The histologicalThe histological
structure of the largestructure of the large
intestineintestine
 TheThe mucosamucosa: th...
The lamina proporiaThe lamina proporia
 It formed of collagen fibers rich in blood vessels andIt formed of collagen fiber...
Large intestineLarge intestine
(cross section(cross section((
AppendixAppendix
Star shaped lumenStar shaped lumen
Mucosa:Mucosa: Simple columnar epithelium with manySimple columnar epi...
AppendixAppendix
The anal canalThe anal canal
 DefinitionDefinition: it is the lower part of the large: it is the lower part of the large
...
The histological structureThe histological structure
of the anal canalof the anal canal
 The mucosaThe mucosa: the upper ...
The musculosaThe musculosa
 It is formed of inner circular layer which isIt is formed of inner circular layer which is
th...
Anal canalAnal canal
Histology of large intestine
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Histology of large intestine

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Histology of large intestine

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Histology of large intestine

  1. 1. Histology ofHistology of Large IntestineLarge Intestine ByBy Muhammad Adan AsgharMuhammad Adan Asghar
  2. 2. ObjectivesObjectives:: --Basic Histology of OrgansBasic Histology of Organs --Histogenisis of Large IntestineHistogenisis of Large Intestine --AppendixAppendix --Anal CanalAnal Canal
  3. 3. ORGANORGAN SS SOLIDSOLID --stromastroma --parenchymaparenchyma HOLLOWHOLLOW --mucosamucosa --submucosasubmucosa --muscularis externamuscularis externa --fibrosafibrosa
  4. 4. Histology of GITHistology of GIT  Schematic diagram showing differentSchematic diagram showing different layers of GITlayers of GIT 1.1. MucosaMucosa 2.2. SubmucosaSubmucosa 3.3. MuscularisMuscularis 4.4. SerosaSerosa
  5. 5. TractTract Common Characteristics: o Hollow tube composed of a lumen whose diameter varies. o Surrounded by a wall made up of 4 principal layers: • Mucosa o Epithelial lining; A lamina propria of loose connective tissues rich in blood, lymph vessels and smooth muscle cells; Muscularis mucosae. • Submucosa o Dense connective tissues with many blood and lymph vessels. • Muscularis o Contains smooth muscle cells, divide into 2 layers; internal (circular); external (longitudinal) • Serosa o Thin layer of loose connective tissue rich in blood and lymph vessels and adipose and single squamous covering epithelium (mesothelium)
  6. 6. The large intestineThe large intestine  The large intestine formed of theThe large intestine formed of the following organs:following organs:  The cecaumThe cecaum  The colonThe colon  The rectumThe rectum  The anal canalThe anal canal
  7. 7. The function of theThe function of the large intestinelarge intestine The absorption of waterThe absorption of water Excluded of the waste productExcluded of the waste product
  8. 8. The histologicalThe histological structure of the largestructure of the large intestineintestine  TheThe mucosamucosa: the epithelium formed of: the epithelium formed of simple columnar ciliated epithelium whichsimple columnar ciliated epithelium which is folded and formed straight glandsis folded and formed straight glands  the epithelium cell formed of two typesthe epithelium cell formed of two types mucus cellsmucus cells for secretion of mucus andfor secretion of mucus and brush cellsbrush cells for absorption of water thefor absorption of water the mucus cells increas and the brush cellsmucus cells increas and the brush cells decrease toward the anal canaldecrease toward the anal canal
  9. 9. The lamina proporiaThe lamina proporia  It formed of collagen fibers rich in blood vessels andIt formed of collagen fibers rich in blood vessels and peyer,s patchespeyer,s patches  TheThe muscularismuscularis mucosamucosa: formed of sheet of smooth: formed of sheet of smooth muscle it is function the conduction of the glandmuscle it is function the conduction of the gland secretionsecretion  TheThe subsub mucosamucosa: formed of loose areolar tissue: formed of loose areolar tissue contain blood vessel, nerve fibers, and lymphaticcontain blood vessel, nerve fibers, and lymphatic tissuetissue  The musculosaThe musculosa: formed of two layers of smooth: formed of two layers of smooth muscle inner circular and outer longitudinal. Themuscle inner circular and outer longitudinal. The longitudinal muscle collected into bands called tenalongitudinal muscle collected into bands called tena collicolli  The serosaThe serosa: formed of mesothelium: formed of mesothelium
  10. 10. Large intestineLarge intestine (cross section(cross section((
  11. 11. AppendixAppendix Star shaped lumenStar shaped lumen Mucosa:Mucosa: Simple columnar epithelium with manySimple columnar epithelium with many goblet cells, Lamina Propria, Muscularis Mucosaegoblet cells, Lamina Propria, Muscularis Mucosae Submucosa:Submucosa: Contain blood vessels and nervesContain blood vessels and nerves Muscularis Externa:Muscularis Externa: Inner circular and outerInner circular and outer longitudinal muscles. No taenia colilongitudinal muscles. No taenia coli Serosa:Serosa: Visceral layer of peritoneumVisceral layer of peritoneum
  12. 12. AppendixAppendix
  13. 13. The anal canalThe anal canal  DefinitionDefinition: it is the lower part of the large: it is the lower part of the large intestineintestine  It is function to give passage for theIt is function to give passage for the feces out side the bodyfeces out side the body
  14. 14. The histological structureThe histological structure of the anal canalof the anal canal  The mucosaThe mucosa: the upper part of the anal canal: the upper part of the anal canal lined by simple columnar while the middle partlined by simple columnar while the middle part lined by stratified squamus non keratinizedlined by stratified squamus non keratinized epithelium and the lower part lined by skinepithelium and the lower part lined by skin  The mucosa fold and formed the anal columnsThe mucosa fold and formed the anal columns  The lamina proporiaThe lamina proporia: formed of collagen: formed of collagen fibers support the mucosafibers support the mucosa  The sub mucosaThe sub mucosa: it is formed of loose tissue: it is formed of loose tissue contain blood vessel, nerve fibers andcontain blood vessel, nerve fibers and lymphaticlymphatic
  15. 15. The musculosaThe musculosa  It is formed of inner circular layer which isIt is formed of inner circular layer which is thick at the lower part and outerthick at the lower part and outer longitudinal layer. There is skeletallongitudinal layer. There is skeletal muscles cover the outer longitudinalmuscles cover the outer longitudinal layerlayer  The serosaThe serosa: formed of connective tissue: formed of connective tissue to support the anal canal with theto support the anal canal with the surrounded tissuesurrounded tissue
  16. 16. Anal canalAnal canal

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