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Preclinical Imaging


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Preclinical Imaging

  1. 1. Preclinical Imaging Research Laboratory (PIRL) Christopher Albanese, Ph.D. Director, PI Olga Rodriguez, MD, Ph.D. Co-Director John VanMeter, Ph.D. Co-Director Yi-Chien Lee, Ph.D. MRI Manager
  2. 2. PIRL Provides: <ul><li>High-end instrumentation, training and expert advice for investigators undertaking in vivo imaging studies </li></ul><ul><li>Users are working on various forms of cancer, using animal models of cancer and testing treatments of cancer </li></ul><ul><li>Rich environment for interactive exchanges and referrals among Lombardi members </li></ul>
  3. 3. PIRL Services: <ul><li>MRI </li></ul><ul><ul><li>2D and 3D anatomical imaging of rats and mice </li></ul></ul><ul><ul><li>Diffusion weighted imaging and mapping </li></ul></ul><ul><ul><li>Volumetric analyses of anatomical features </li></ul></ul><ul><ul><li>Magnetic Resonance Spectroscopy </li></ul></ul><ul><ul><li>Image Reconstruction and analysis </li></ul></ul>
  4. 4. PIRL Services: <ul><li>Maestro II </li></ul><ul><ul><li>Fluorescence and bioluminescence imaging from visible to near infrared (mice, rats) </li></ul></ul><ul><ul><li>Quantitative </li></ul></ul><ul><ul><li>Spectroscopic Analyses </li></ul></ul>
  5. 5. PIRL Services: <ul><li>VEVO660 </li></ul><ul><ul><li>High resolution ultrasound (mice, rats) </li></ul></ul><ul><ul><li>Image reconstruction and analysis </li></ul></ul><ul><ul><li>(Pictured to the right) </li></ul></ul><ul><li>Faxitron </li></ul><ul><ul><li>X-ray imaging of small animals (rats, mice) </li></ul></ul>
  6. 6. Equipment Applications <ul><li>PIRL-developed 3D anatomical </li></ul><ul><li>MRI sequences </li></ul><ul><li>Imaging of lung metastases using Maestro II and fluorescent nanoparticles </li></ul>(Chang)
  7. 7. PIRL Training: <ul><li>Training of users: </li></ul><ul><li>lectures, courses, hands-on instrument operation, and individual instruction </li></ul><ul><li>Trained users can operate : </li></ul><ul><li>imaging equipment or can request technical assistance </li></ul>
  8. 8. PIRL Contacts <ul><li>Chip Albanese, PhD </li></ul><ul><li>Core Director </li></ul><ul><ul><li>x7-3305 </li></ul></ul><ul><ul><li>[email_address] </li></ul></ul><ul><li>Olga Rodriguez, MD, PhD </li></ul><ul><li>Core Co-Director </li></ul><ul><ul><li>x7-4628 </li></ul></ul><ul><ul><li>[email_address] </li></ul></ul><ul><li>Magnet Lab </li></ul><ul><ul><li>x7-4802 </li></ul></ul>
  9. 9. Shared Resources are partially supported by the Georgetown Howard University Center for Clinical and Translational Studies (GHUCCTS) 1UL1RR031975-01    In your publications, remember to mention support provided from the GHUCCTS.