Biostatistics & Bioinformatics

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Biostatistics & Bioinformatics

  1. 1. Biostatistics and Bioinformatics Shared Resource (BBSR) Dr. Christopher Loffredo Co Director Kepher Makambi, PhD Co Director Statistical analysis Clinical Trials Support Bioinformatics
  2. 2. BBSR Services <ul><li>Biostatistics and Bioinformatics provide : </li></ul><ul><li>Support for data analysis from basic science, clinical, and population science research projects. </li></ul><ul><li>Support for planning, analysis, and monitoring of clinical trials. </li></ul><ul><li>Support for grant proposals, including power and sample size estimation, and data analysis planning. </li></ul>
  3. 3. Examples of Science Supported by the BBSR Microarray analysis Proteomic and Metabolomic analysis Models of Cancer Risk Efficacy of randomized treatment Forecasting of cancer trends
  4. 4. Hardware Resources <ul><li>Dell desktop-class computers: Windows and Linux OS </li></ul><ul><li>Central processing and file storage servers: 64bit AMD Opterons running RedHat Enterprise </li></ul><ul><li>Quad-core computer: dedicated to web applications </li></ul><ul><li>Development servers : 2 Quad-Core Intel CPUs, using CentOS 5.0 Linux to support Oracle 11g, MySQL 5.0, PostgreSQL, a Web server (Apache), an application server (JBOSS), and development tools. </li></ul>All applications are scalable to meet the needs of users
  5. 5. Software Resources <ul><li>General: SAS, GAUSS, MATHEMATICA, STATISTICA, StatXact, R, MATLAB, SPSS </li></ul><ul><li>Experimental Design: Simon’s Phase II, PS, NQuery, StPlan, Bayesian Plans for Phase II Trials, Power and Precision </li></ul><ul><li>Specialized Packages: CART, Mplus </li></ul>
  6. 6. Software Resources <ul><li>Bioinformatics: Bioconductor, DCHIP, PDQuest, PAUP, BRB-Array Tools </li></ul><ul><li>Database: MySQL, Oracle, Oracle Jdeveloper </li></ul><ul><li>Programming: Java, IMSL, Perl, PHP, VB/ASP, Weka, C, C++ </li></ul><ul><li>Optimization : MOZEK </li></ul>
  7. 7. For More Information Contact Christopher Loffredo,PhD, Director [email_address] or Kepher Makambi, PhD Co Director [email_address] Caroline Wu [email_address] http://lombardi.georgetown.edu/research/sharedresources/bbsr/index.html
  8. 8. Shared Resources are partially supported by the Georgetown Howard University Center for Clinical and Translational Studies (GHUCCTS) 1UL1RR031975-01    In your publications, remember to mention support provided from the GHUCCTS.

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