2628696031021875

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2628696031021875

  1. 1. Power of Biotechnology Can change to
  2. 2. What biotechnology can do? <ul><li>Sequence the human genome, as well as genome of flies, worms, mice and many other bacteria. </li></ul><ul><li>Can cut chromosomes in specified places using enzymes that works as “ molecular scissors”. </li></ul><ul><li>Insert a new genes in chromosomes. </li></ul><ul><li>Use proteins to start or stop the transcription of DNA into RNA and proteins. </li></ul>
  3. 3. More features of biotechnology <ul><li>Knock out certain genes in mice or other organisms that control metabolic pathways or create disease (great for science) </li></ul><ul><li>Compare genes in one species with gene from different species to see how metabolic functions have evolved. </li></ul><ul><li>Insert new genes in bacteria and viruses. </li></ul><ul><li>Can produce new species of plants and animals. </li></ul>
  4. 4. Why is the sequencing of human genomes important? <ul><li>Demonstrate the similarities between humans and other organisms </li></ul><ul><li>Demonstrate the complexity of most cell function </li></ul><ul><li>Failed to provide the answer to genetic control of most disease </li></ul>
  5. 6. Genomics – from chromosomes to function <ul><li>Start with sequencing of chromosomes- or start with identifying the location of the gene of interest </li></ul><ul><li>Use radioactively labeled nucleotides to determine sequence of DNA segment </li></ul><ul><li>Compare sequence to huge databases of genetic data using sophisticated computer tools </li></ul>
  6. 7. Genetic sequence of bacteria and viruses <ul><li>May give us clues to function </li></ul><ul><li>- Genetic sequence have helped us to understand variations in viruses </li></ul><ul><li>Identifies how traits are passed horizontally </li></ul><ul><li>Can be used to trace epidemics geographically </li></ul>
  7. 8. Human Genome

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